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Sequence of FTMB_ASPFU

EC Number:2.5.1.106

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
tryprostatin B synthase
Q4WAW7
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
464
52607
Reaction
dimethylallyl diphosphate + brevianamide F = diphosphate + tryprostatin B
Other sequences found for EC No. 2.5.1.106

General information:

Sequence
show sequence in fasta format
  0 MPPAPPDQKP CHQLQPAPYR ALSESILFGS VDEERWWHST APILSRLLIS SNYDVDVQYK
 60 YLSLYRHLVL PALGPYPQRD PETGIIATQW RSGMVLTGLP IEFSNNVARA LIRIGVDPVT
120 ADSGTAQDPF NTTRPKVYLE TAARLLPGVD LTRFYEFETE LVITKAEEAV LQANPDLFRS
180 PWKSQILTAM DLQKSGTVLV KAYFYPQPKS AVTGRSTEDL LVNAIRKVDR EGRFETQLAN
240 LQRYIERRRR GLHVPGVTAD KPPATAADKA FDACSFFPHF LSTDLVEPGK SRVKFYASER
300 HVNLQMVEDI WTFGGLRRDP DALRGLELLR HFWADIQMRE GYYTMPRGFC ELGKSSAGFE
360 APMMFHFHLD GSQSPFPDPQ MYVCVFGMNS RKLVEGLTTF YRRVGWEEMA SHYQGNFLAN
420 YPDEDFEKAA HLCAYVSFAY KNGGAYVTLY NHSFNPVGDV SFPN
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
35386
Grundmann A.,Li S.M.
Overproduction, purification and characterization of FtmPT1, a brevianamide F prenyltransferase from Aspergillus fumigatus.
Microbiology
151
2199-2207
2005
35387
Nierman W.C.,Pain A.,Anderson M.J.,Wortman J.R.,Kim H.S.,Arroyo J.,Berriman M.,Abe K.,Archer D.B.,Bermejo C.,Bennett J.W.,Bowyer P.,Chen D.,Collins M.,Coulsen R.,Davies R.,Dyer P.S.,Farman M.L.,Fedorova N.,Fedorova N.D.,Feldblyum T.V.,Fischer R.,Fosker N.,Fraser A.,Garcia J.L.,Garcia M.J.,Goble A.,Goldman G.H.,Gomi K.,Griffith-Jones S.,Gwilliam R.,Haas B.J.,Haas H.,Harris D.E.,Horiuchi H.,Huang J.,Humphray S.,Jimenez J.,Keller N.,Khouri H.,Kitamoto K.,Kobayashi T.,Konzack S.,Kulkarni R.,Kumagai T.,Lafton A.,Latge J.-P.,Li W.,Lord A.,Lu C.,Majoros W.H.,May G.S.,Miller B.L.,Mohamoud Y.,Molina M.,Monod M.,Mouyna I.,Mulligan S.,Murphy L.D.,O'Neil S.,Paulsen I.,Penalva M.A.,Pertea M.,Price C.,Pritchard B.L.,Quail M.A.,Rabbinowitsch E.,Rawlins N.,Rajandream M.A.,Reichard U.,Renauld H.,Robson G.D.,Rodriguez de Cordoba S.,Rodriguez-Pena J.M.,Ronning C.M.,Rutter S.,Salzberg S.L.,Sanchez M.,Sanchez-Ferrero J.C.,Saunders D.,Seeger K.,Squares R.,Squares S.,Takeuchi M.,Tekaia F.,Turner G.,Vazquez de Aldana C.R.,Weidman J.,White O.,Woodward J.R.,Yu J.-H.,Fraser C.M.,Galagan J.E.,Asai K.,Machida M.,Hall N.,Barrell B.G.,Denning D.W.
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus.
Nature
438
1151-1156
2005
35388
Maiya S.,Grundmann A.,Li S.M.,Turner G.
The fumitremorgin gene cluster of Aspergillus fumigatus: identification of a gene encoding brevianamide F synthetase.
ChemBioChem
7
1062-1069
2006
35389
Grundmann A.,Kuznetsova T.,Afiyatullov S.S.,Li S.M.
FtmPT2, an N-prenyltransferase from Aspergillus fumigatus, catalyses the last step in the biosynthesis of fumitremorgin B.
ChemBioChem
9
2059-2063
2008
35390
Kato N.,Suzuki H.,Takagi H.,Asami Y.,Kakeya H.,Uramoto M.,Usui T.,Takahashi S.,Sugimoto Y.,Osada H.
Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.
ChemBioChem
10
920-928
2009
35391
Steffan N.,Grundmann A.,Afiyatullov S.,Ruan H.,Li S.M.
FtmOx1, a non-heme Fe(II) and alpha-ketoglutarate-dependent dioxygenase, catalyses the endoperoxide formation of verruculogen in Aspergillus fumigatus.
Org. Biomol. Chem.
7
4082-4087
2009
35392
Wollinsky B.,Ludwig L.,Xie X.,Li S.M.
Breaking the regioselectivity of indole prenyltransferases: identification of regular C3-prenylated hexahydropyrrolo[2,3-b]indoles as side products of the regular C2-prenyltransferase FtmPT1.
Org. Biomol. Chem.
10
9262-9270
2012
35393
Kato N.,Suzuki H.,Okumura H.,Takahashi S.,Osada H.
A point mutation in ftmD blocks the fumitremorgin biosynthetic pathway in Aspergillus fumigatus strain Af293.
Biosci. Biotechnol. Biochem.
77
1061-1067
2013
35394
Jost M.,Zocher G.,Tarcz S.,Matuschek M.,Xie X.,Li S.M.,Stehle T.
Structure-function analysis of an enzymatic prenyl transfer reaction identifies a reaction chamber with modifiable specificity.
J. Am. Chem. Soc.
132
17849-17858
2010