Sequence of REBG_LENAE
EC Number:4.3.3.5
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
4'-O-demethylrebeccamycin + H2O = dichloro-arcyriaflavin A + beta-D-glucose
Other sequences found for EC No. 4.3.3.5
General information:
Sequence
0 MGARVLVATT PGDGHVNPMV PVAQEMVSRG HEVRWYTGKA FRSTVERTGA RHEPMRDAHD
60 FGGMPREEAF PQHAGLTGIT GMIAGFRDIF IEPAADQMTD LLALLEDFPA DVLVTDETFF
120 GAGFVSERTG IPVAWIATSI YVFSSRDTAP LGLGLPPSSS RLGRLRNTVL KQLTDRVVMR
180 DLRRHADVVR DRVGLPRIRK GAFENIMRTP DLYLLGTVPS FEYPRGDMPP EVRFVGPFVS
240 PAPPDFTPPA WWGELDSGRP VVHVTQGTVA NDAERLLLPA IRALAAEDVL VVATTGAPLE
300 LEPMPANVRV ERFIPHHALL PHVDAMVTNG GYGGVNTALA HGVPLVVAAA TEEKHEVAAR
360 VSWSGAGVHL KKRRLSERDI RRAVRAVLDE PRFRVHAARL RDEYAARDAV VDAVDLIEGL
420 V
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
343546
Ohuchi T.,Ikeda-Araki A.,Watanabe-Sakamoto A.,Kojiri K.,Nagashima M.,Okanishi M.,Suda H.
Cloning and expression of a gene encoding N-glycosyltransferase (ngt) from Saccarothrix aerocolonigenes ATCC39243.
J. Antibiot.
53
393-403
2000
343547
Sanchez C.,Butovich I.A.,Brana A.F.,Rohr J.,Mendez C.,Salas J.A.
The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives.
Chem. Biol.
9
519-531
2002
343548
Onaka H.,Taniguchi S.,Igarashi Y.,Furumai T.
Cloning of the staurosporine biosynthetic gene cluster from Streptomyces sp. TP-A0274 and its heterologous expression in Streptomyces lividans.
J. Antibiot.
55
1063-1071
2002
343549
Hyun C.G.,Bililign T.,Liao J.,Thorson J.S.
The biosynthesis of indolocarbazoles in a heterologous E. coli host.
ChemBioChem
4
114-117
2003
343550
Nishizawa T.,Aldrich C.C.,Sherman D.H.
Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243.
J. Bacteriol.
187
2084-2092
2005
343551
Onaka H.,Taniguchi S.,Igarashi Y.,Furumai T.
Characterization of the biosynthetic gene cluster of rebeccamycin from Lechevalieria aerocolonigenes ATCC 39243.
Biosci. Biotechnol. Biochem.
67
127-138
2003
343552
Zhang C.,Albermann C.,Fu X.,Peters N.R.,Chisholm J.D.,Zhang G.,Gilbert E.J.,Wang P.G.,Van Vranken D.L.,Thorson J.S.
RebG- and RebM-catalyzed indolocarbazole diversification.
ChemBioChem
7
795-804
2006
