Sequence of POLG_EC01F
EC Number:3.4.22.28
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Selective cleavage of Gln-/-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly
Other sequences found for EC No. 3.4.22.28
General information:
Sequence
0 MGAQVSTQKT GAHETSLSAT GNSIIHYTNI NYYKDAASNS ANRQDFTQDP GKFTEPMKDV
60 MIKTLPALNS PTVEECGYSD RVRSITLGNS TITTQECANV VVGYGEWPEY LSDNEATAED
120 QPTQPDVATC RFYTLDSVQW ENGSPGWWWK FPDALRDMGL FGQNMYYHYL GRAGYTIHVQ
180 CNASKFHQGC ILVVCVPEAE MGSAQTSGVV NYEHISKGEI ASRFTTTTTA EDHGVQAAVW
240 NAGMGVGVGN LTIFPHQWIN LRTNNSATIV MPYVNSVPMD NMYRHHNFTL MIIPFVPLDF
300 SAGASTYVPI TVTVAPMCAE YNGLRLAGHQ GLPTMNTPGS NQFLTSDDFQ SPSAMPQFDV
360 TPEMHIPGEV RNLMEIAEVD SVMPINNDSA AKVSSMEAYR VELSTNTNAG TQVFGFQLNP
420 GAESVMNRTL MGEILNYYAH WSGSIKITFV FCGSAMTTGK FLLSYAPPGA GAPKTRKDAM
480 LGTHVVWDVG LQSSCVLCIP WISQTHYRFV EKDPYTNAGF VTCWYQTSVV SPASNQPKCY
540 MMCMVSACND FSVRMLRDTK FIEQTSFYQG DVQNAVEGAM VRVADTVQTS ATNSERVPNL
600 TAVETGHTSQ AVPGDTMQTR HVINNHVRSE STIENFLARS ACVFYLEYKT GTKEDSNSFN
660 NWVITTRRVA QLRRKLEMFT YLRFDMEITV VITSSQDQST SQNQNAPVLT HQIMYVPPGG
720 PIPVSVDDYS WQTSTNPSIF WTEGNAPARM SIPFISIGNA YSNFYDGWSH FSQAGVYGFT
780 TLNNMGQLFF RHVNKPNPAA ITSVARIYFK PKHVRAWVPR PPRLCPYINS TNVNFEPKPV
840 TEVRTNIITT GAFGQQSGAV YVGNYRVVNR HLATHIDWQN CVWEDYNRDL LVSTTTAHGC
900 DTIARCQCTT GVYFCLSRNK HYPVSFEGPG LVEVQESEYY PKRYQSHVLL AAGFSEPGDC
960 GGILRCEHGV IGIVTMGGEG VVGFADVRDL LWLEDDAMEQ GVKDYVEQLG NAFGSGFTNQ
1020 ICEQVNLLKE SLVGQDSILE KSLKALVKII SALVIVVRNH DDLITVTATL ALIGCTSSPW
1080 RWLKQKVSQY YGIPMAERQN NGWLKKFTEM TNACKGMEWI AIKIQKFIEW LKVKILPEVK
1140 EKHEFLNRLK QLPLLESQIA TIEQSAPSQG DQEQLFSNVQ YFAHYCRKYA PLYAAEAKRV
1200 FSLEKKMSNY IQFKSKCRIE PVCLLLHGSP GAGKSVATNL IGRSLAEKLN SSVYSLPPDP
1260 DHFDGYKQQA VVIMDDLCQN PDGKDVSLFC QMVSSVDFVP PMAALEEKGI LFTSPFVLAS
1320 TNAGSINAPT VSDSRALARR FHFDMNIEVI SMYSQNGKIN MPMSVKTCDE DCCPVNFKKC
1380 CPLVCGKAIQ FIDRKTQVRY SLDMLVTEMF REYNHRHSVG ATLEALFQGP PVYREIKISV
1440 APETPPPPAI ADLLKSVDSE AVREYCKEKG WLVPEISSTL QIEKHVSRAF ICLQALTTFV
1500 SVAGIIYIIY KLFAGFQGAY TGMPNQKPKV PTLRQAKVQG PAFEFAVAMM KRNASTVKTE
1560 YGEFTMLGIY DRWAVLPRHA KPGPTILMND QEVGVLDAKE LVDKDGTNLE LTLLKLNRNE
1620 KFRDIRGFLA REEAEVNEAV LAINTSKFPN MYIPVGQVTD YGFLNLGGTP TKRMLMYNFP
1680 TRAGQCGGVL MSTGKVLGIH VGGNGHQGFS AALLRHYFNE EQGEIEFIES SKDAGFPVIN
1740 TPSKTKLEPS VFHQVFEGNK EPAVLRNGDP RLKVNFEEAI FSKYIGNVNT HVDEYMQEAV
1800 DHYAGQLATL DISTEPMKLE DAVYGTEGLE ALDLTTSAGY PYVALGIKKR DILSKKTKDL
1860 TKLKECMDKY GLNLPMVTYV KDELRSAEKV AKGKSRLIEA SSLNDSVAMR QTFGNLYKTF
1920 HLNPGIVTGS AVGCDPDVFW SKIPVMLDGH LIAFDYSGYD ASLSPVWFAC LKLLLEKLGY
1980 TNKETNYIDY LCNSHHLYRD KHYFVRGGMP SGCSGTSIFN SMINNIIIRT LMLKVYKGID
2040 LDQFRMIAYG DDVIASYPWP IDASLLAEAG KDYGLIMTPA DKGECFNEVT WTNVTFLKRY
2100 FRADEQYPFL VHPVMPMKDI HESIRWTKDP KNTQDHVRSL CLLAWHNGEH EYEEFIRKIR
2160 SVPVGRCLTL PAFSTLRRKW LDSF
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
335816
Huttunen P.,Santti J.,Pulli T.,Hyypiae T.
The major echovirus group is genetically coherent and related to coxsackie B viruses.
J. Gen. Virol.
77
715-725
1996
335817
Oberste M.S.,Maher K.,Kilpatrick D.R.,Pallansch M.A.
Molecular evolution of the human enteroviruses: correlation of serotype with VP1 sequence and application to picornavirus classification.
J. Virol.
73
1941-1948
1999
335818
Bergelson J.M.,St John N.,Kawaguchi S.,Chan M.,Stubdal H.,Modlin J.,Finberg R.W.
Infection by echoviruses 1 and 8 depends on the alpha 2 subunit of human VLA-2.
J. Virol.
67
6847-6852
1993
335819
Marjomaki V.,Pietiainen V.,Matilainen H.,Upla P.,Ivaska J.,Nissinen L.,Reunanen H.,Huttunen P.,Hyypia T.,Heino J.
Internalization of echovirus 1 in caveolae.
J. Virol.
76
1856-1865
2002
335820
Pietiainen V.,Marjomaki V.,Upla P.,Pelkmans L.,Helenius A.,Hyypia T.
Echovirus 1 endocytosis into caveosomes requires lipid rafts, dynamin II, and signaling events.
Mol. Biol. Cell
15
4911-4925
2004
335821
Filman D.J.,Wien M.W.,Cunningham J.A.,Bergelson J.M.,Hogle J.M.
Structure determination of echovirus 1.
Acta Crystallogr. D
54
1261-1272
1998
