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Sequence of OCH1_YEAST

EC Number:2.4.1.232

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
initiation-specific alpha-1,6-mannosyltransferase
P31755
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
480
55156
Reaction
GDP-mannose + Man8GlcNAc = GDP + Man9GlcNAc
Other sequences found for EC No. 2.4.1.232

General information:

Sequence
show sequence in fasta format
  0 MSRKLSHLIA TRKSKTIVVT VLLIYSLLTF HLSNKRLLSQ FYPSKDDFKQ TLLPTTSHSQ
 60 DINLKKQITV NKKKNQLHNL RDQLSFAFPY DSQAPIPQRV WQTWKVGADD KNFPSSFRTY
120 QKTWSGSYSP DYQYSLISDD SIIPFLENLY APVPIVIQAF KLMPGNILKA DFLRYLLLFA
180 RGGIYSDMDT MLLKPIDSWP SQNKSWLNNI IDLNKPIPYK NSKPSLLSSD EISHQPGLVI
240 GIEADPDRDD WSEWYARRIQ FCQWTIQAKP GHPILRELIL NITATTLASV QNPGVPVSEM
300 IDPRFEEDYN VNYRHKRRHD ETYKHSELKN NKNVDGSDIM NWTGPGIFSD IIFEYMNNVL
360 RYNSDILLIN PNLNKNDEEG SESATTPAKD VDNDTLSKST RKFYKKISES LQSSNSMPWE
420 FFSFLKEPVI VDDVMVLPIT SFSPDVGQMG AQSSDDKMAF VKHMFSGSWK EDADKNAGHK
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
328532
Nakayama K.,Nagasu T.,Shimma Y.,Kuromitsu J.-R.,Jigami Y.
OCH1 encodes a novel membrane bound mannosyltransferase: outer chain elongation of asparagine-linked oligosaccharides.
EMBO J.
11
2511-2519
1992
328533
Tettelin H.,Agostoni-Carbone M.L.,Albermann K.,Albers M.,Arroyo J.,Backes U.,Barreiros T.,Bertani I.,Bjourson A.J.,Brueckner M.,Bruschi C.V.,Carignani G.,Castagnoli L.,Cerdan E.,Clemente M.L.,Coblenz A.,Coglievina M.,Coissac E.,Defoor E.,Del Bino S.,Delius H.,Delneri D.,de Wergifosse P.,Dujon B.,Durand P.,Entian K.-D.,Eraso P.,Escribano V.,Fabiani L.,Fartmann B.,Feroli F.,Feuermann M.,Frontali L.,Garcia-Gonzalez M.,Garcia-Saez M.I.,Goffeau A.,Guerreiro P.,Hani J.,Hansen M.,Hebling U.,Hernandez K.,Heumann K.,Hilger F.,Hofmann B.,Indge K.J.,James C.M.,Klima R.,Koetter P.,Kramer B.,Kramer W.,Lauquin G.,Leuther H.,Louis E.J.,Maillier E.,Marconi A.,Martegani E.,Mazon M.J.,Mazzoni C.,McReynolds A.D.K.,Melchioretto P.,Mewes H.-W.,Minenkova O.,Mueller-Auer S.,Nawrocki A.,Netter P.,Neu R.,Nombela C.,Oliver S.G.,Panzeri L.,Paoluzi S.,Plevani P.,Portetelle D.,Portillo F.,Potier S.,Purnelle B.,Rieger M.,Riles L.,Rinaldi T.,Robben J.,Rodrigues-Pousada C.,Rodriguez-Belmonte E.,Rodriguez-Torres A.M.,Rose M.,Ruzzi M.,Saliola M.,Sanchez-Perez M.,Schaefer B.,Schaefer M.,Scharfe M.,Schmidheini T.,Schreer A.,Skala J.,Souciet J.-L.,Steensma H.Y.,Talla E.,Thierry A.,Vandenbol M.,van der Aart Q.J.M.,Van Dyck L.,Vanoni M.,Verhasselt P.,Voet M.,Volckaert G.,Wambutt R.,Watson M.D.,Weber N.,Wedler E.,Wedler H.,Wipfli P.,Wolf K.,Wright L.F.,Zaccaria P.,Zimmermann M.,Zollner A.,Kleine K.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Nature
387
81-84
1997
328534
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
328535
Hu Y.,Rolfs A.,Bhullar B.,Murthy T.V.S.,Zhu C.,Berger M.F.,Camargo A.A.,Kelley F.,McCarron S.,Jepson D.,Richardson A.,Raphael J.,Moreira D.,Taycher E.,Zuo D.,Mohr S.,Kane M.F.,Williamson J.,Simpson A.J.G.,Bulyk M.L.,Harlow E.,Marsischky G.,Kolodner R.D.,LaBaer J.
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
Genome Res.
17
536-543
2007
328536
Nagasu T.,Shimma Y.,Nakanishi Y.,Kuromitsu J.,Iwama K.,Nakayama K.,Suzuki K.,Jigami Y.
Isolation of new temperature-sensitive mutants of Saccharomyces cerevisiae deficient in mannose outer chain elongation.
Yeast
8
535-547
1992
328537
Nakanishi-Shindo Y.,Nakayama K.,Tanaka A.,Toda Y.,Jigami Y.
Structure of the N-linked oligosaccharides that show the complete loss of alpha-1,6-polymannose outer chain from och1, och1 mnn1, and och1 mnn1 alg3 mutants of Saccharomyces cerevisiae.
J. Biol. Chem.
268
26338-26345
1993
328538
Lehle L.,Eiden A.,Lehnert K.,Haselbeck A.,Kopetzki E.
Glycoprotein biosynthesis in Saccharomyces cerevisiae: ngd29, an N-glycosylation mutant allelic to och1 having a defect in the initiation of outer chain formation.
FEBS Lett.
370
41-45
1995
328539
Harris S.L.,Waters M.G.
Localization of a yeast early Golgi mannosyltransferase, Och1p, involves retrograde transport.
J. Cell Biol.
132
985-998
1996
328540
Horecka J.,Sprague G.F. Jr.
Use of imidazoleglycerolphosphate dehydratase (His3) as a biological reporter in yeast.
Methods Enzymol.
326
107-119
2000
328541
Cullen P.J.,Schultz J.,Horecka J.,Stevenson B.J.,Jigami Y.,Sprague G.F. Jr.
Defects in protein glycosylation cause SHO1-dependent activation of a STE12 signaling pathway in yeast.
Genetics
155
1005-1018
2000
328542
Li S.,Dean S.,Li Z.,Horecka J.,Deschenes R.J.,Fassler J.S.
The eukaryotic two-component histidine kinase Sln1p regulates OCH1 via the transcription factor, Skn7p.
Mol. Biol. Cell
13
412-424
2002
328543
Cui Z.,Horecka J.,Jigami Y.
Cdc4 is involved in the transcriptional control of OCH1, a gene encoding alpha-1,6-mannosyltransferase in Saccharomyces cerevisiae.
Yeast
19
69-77
2002
328544
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
328545
Bruinsma P.,Spelbrink R.G.,Nothwehr S.F.
Retrograde transport of the mannosyltransferase Och1p to the early Golgi requires a component of the COG transport complex.
J. Biol. Chem.
279
39814-39823
2004
328546
Karhinen L.,Makarow M.
Activity of recycling Golgi mannosyltransferases in the yeast endoplasmic reticulum.
J. Cell Sci.
117
351-358
2004
328547
Kitajima T.,Chiba Y.,Jigami Y.
Saccharomyces cerevisiae alpha1,6-mannosyltransferase has a catalytic potential to transfer a second mannose molecule.
FEBS J.
273
5074-5085
2006
328548
Hirayama H.,Suzuki T.
Metabolism of free oligosaccharides is facilitated in the och1Delta mutant of Saccharomyces cerevisiae.
Glycobiology
21
1341-1348
2011
328549
Chantret I.,Kodali V.P.,Lahmouich C.,Harvey D.J.,Moore S.E.
Endoplasmic reticulum-associated degradation (ERAD) and free oligosaccharide generation in Saccharomyces cerevisiae.
J. Biol. Chem.
286
41786-41800
2011