Sequence of NOTF_ASPSM
EC Number:2.5.1.109
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
brevianamide F prenyltransferase (deoxybrevianamide E-forming)
E0Y3X1
Aspergillus sp. (strain MF297-2)
452
51608
Reaction
dimethylallyl diphosphate + brevianamide F = diphosphate + deoxybrevianamide E
Other sequences found for EC No. 2.5.1.109
General information:
Sequence
0 MTAPELRVDT FRAPEDAPKE PSAQQPRLPS SPSPAQALAS YHHFPTNDQE RWWEETGSLF
60 SRFLEAGQYG LPQQYQFMFF FMHHLIPALG PYPQKWRSTI SRSGLPIEFS LNFQKGSHRL
120 LRIGFEPVSF LSGSSQDPFN RIPITDLLNR LSKLQLSNFD TPFFQHLLSK FQLSLSEVRQ
180 LQKQGSGPDA HPLKSQAAFG FDFNPDGAIL VKGYVFPYLK AKAADVPVGT LIAEAVRTID
240 VERNQFTHAF GLINDYMQES TGYNEYTFLS CDFVETSEQR LKIYGAHTEV TWAKIAEMWT
300 LGGRLIEEPE IIAGLARLKQ IWSLLQIGEG SRAFKGGFDY DKSSATDQIA SPIIWNYEIH
360 PGSRFPVPKF YLPVHGENDL HVARALAQFW DSLGWPEHAC AYPDTLQQLY PDQDISQTTR
420 LQSWISYSYT AKRGVYMSVY YHSQSTYLWE ED
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
325908
Ding Y.,de Wet J.R.,Cavalcoli J.,Li S.,Greshock T.J.,Miller K.A.,Finefield J.M.,Sunderhaus J.D.,McAfoos T.J.,Tsukamoto S.,Williams R.M.,Sherman D.H.
Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived Aspergillus sp.
J. Am. Chem. Soc.
132
12733-12740
2010
325909
Kato H.,Yoshida T.,Tokue T.,Nojiri Y.,Hirota H.,Ohta T.,Williams R.M.,Tsukamoto S.
Notoamides A-D: prenylated indole alkaloids isolated from a marine-derived fungus, Aspergillus sp.
Angew. Chem. Int. Ed.
46
2254-2256
2007
325910
Li S.,Finefield J.M.,Sunderhaus J.D.,McAfoos T.J.,Williams R.M.,Sherman D.H.
Biochemical characterization of NotB as an FAD-dependent oxidase in the biosynthesis of notoamide indole alkaloids.
J. Am. Chem. Soc.
134
788-791
2012
325911
Li S.,Anand K.,Tran H.,Yu F.,Finefield J.M.,Sunderhaus J.D.,McAfoos T.J.,Tsukamoto S.,Williams R.M.,Sherman D.H.
Comparative analysis of the biosynthetic systems for fungal bicyclo[2.2.2]diazaoctane indole alkaloids: the (+)/(-)-notoamide, paraherquamide and malbrancheamide pathways.
Med. Chem. Commun.
3
987-996
2012
