Sequence of PGL3_CAEEL

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ribonuclease T1
G5EBV6
Caenorhabditis elegans
693
74845
Reaction
two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MEANKRQIVE VDGIKSYFFP HLAHYLASND ELLVNNIAQA NKLAAFVLGA TDKRPSNEEI
 60 AEMILPNDSS AYVLAAGMDV CLILGDDFRP KFDSGAEKLS QLGQAHDLAP IIDDEKKISM
120 LARKTKLKKS NDAKILQVLL KVLGAEEAEE KFVELSELSS ALDLDFDVYV LAKLLGFASE
180 ELQEEIEIIR DNVTDAFEAC KPLLKKLMIE GPKIDSVDPF TQLLLTPQEE SIEKAVSHIV
240 ARFEEASAVE DDESLVLKSQ LGYQLIFLVV RSLADGKRDA SRTIQSLMPS SVRAEVFPGL
300 QRSVFKSAVF LASHIIQVFL GSMKSFEDWA FVGLAEDLES TWRRRAIAEL LKKFRISVLE
360 QCFSQPIPLL PQSELNNETV IENVNNALQF ALWITEFYGS ESEKKSLNQL QFLSPKSKNL
420 LVDSFKKFAQ GLDSKDHVNR IIESLEKSSS SEPSATAKQT TTSNGPTTVS TAAQVVTVEK
480 MPFSRQTIPC EGTDLANVLN SAKIIGESVT VAAHDVIPEK LNAEKNDNTP STASPVQFSS
540 DGWDSPTKSV ALPPKISTLE EEQEEDTTIT KVSPQPQERT GTAWGSGDAT PVPLATPVNE
600 YKVSGFGAAP VASGFGQFAS SNGTSGRGSY GGGRGGDRGG RGAYGGDRGR GGSGDGSRGY
660 RGGDRGGRGS YGEGSRGYQG GRAGFFGGSR GGS
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
324743
Kawasaki I.,Amiri A.,Fan Y.,Meyer N.,Dunkelbarger S.,Motohashi T.,Karashima T.,Bossinger O.,Strome S.
The PGL family proteins associate with germ granules and function redundantly in Caenorhabditis elegans germline development.
Genetics
167
645-661
2004
324744
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
324745
Zhao Y.,Tian E.,Zhang H.
Selective autophagic degradation of maternally-loaded germline P granule components in somatic cells during C. elegans embryogenesis.
Autophagy
5
717-719
2009
324746
Zhang Y.,Yan L.,Zhou Z.,Yang P.,Tian E.,Zhang K.,Zhao Y.,Li Z.,Song B.,Han J.,Miao L.,Zhang H.
SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans.
Cell
136
308-321
2009
324747
Hanazawa M.,Yonetani M.,Sugimoto A.
PGL proteins self associate and bind RNPs to mediate germ granule assembly in C. elegans.
J. Cell Biol.
192
929-937
2011
324748
Li S.,Yang P.,Tian E.,Zhang H.
Arginine methylation modulates autophagic degradation of PGL granules in C. elegans.
Mol. Cell
52
421-433
2013
324749
Updike D.L.,Knutson A.K.,Egelhofer T.A.,Campbell A.C.,Strome S.
Germ-granule components prevent somatic development in the C. elegans germline.
Curr. Biol.
24
970-975
2014
324750
Saha S.,Weber C.A.,Nousch M.,Adame-Arana O.,Hoege C.,Hein M.Y.,Osborne-Nishimura E.,Mahamid J.,Jahnel M.,Jawerth L.,Pozniakovski A.,Eckmann C.R.,Juelicher F.,Hyman A.A.
Polar positioning of phase-separated liquid compartments in cells regulated by an mRNA competition mechanism.
Cell
166
1572-1584
2016
324751
Min H.,Shim Y.H.,Kawasaki I.
Loss of PGL-1 and PGL-3, members of a family of constitutive germ-granule components, promotes germline apoptosis in C. elegans.
J. Cell Sci.
129
341-353
2016
324752
Aoki S.T.,Kershner A.M.,Bingman C.A.,Wickens M.,Kimble J.
PGL germ granule assembly protein is a base-specific, single-stranded RNase.
Proc. Natl. Acad. Sci. U.S.A.
113
1279-1284
2016
324753
Al-Amin M.,Min H.,Shim Y.H.,Kawasaki I.
Somatically expressed germ-granule components, PGL-1 and PGL-3, repress programmed cell death in C. elegans.
Sci. Rep.
6
33884-33884
2016
324754
Zhang G.,Lin L.,Qi D.,Zhang H.
The composition of a protein aggregate modulates the specificity and efficiency of its autophagic degradation.
Autophagy
13
1487-1495
2017