Sequence of COABC_MYCS2
EC Number:6.3.2.5
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
phosphopantothenate-cysteine ligase (CTP)
A0QWT2
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
414
43152
Reaction
CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + N-[(R)-4'-phosphopantothenoyl]-L-cysteine
General information:
Sequence
0 MSARKRIVVG VAGGIAAYKA CTVVRQLTEA GHSVRVVPTE SALRFVGAAT FEALSGNPVH
60 TGVFTDVHEV QHVRIGQQAD LVVIAPATAD LLARAVAGRA DDLLTATLLT ARCPVLFAPA
120 MHTEMWLHPA TVDNVATLRR RGAVVLEPAS GRLTGADSGP GRLPEAEEIT TLAQLLLERA
180 DALPYDMAGV KALVTAGGTR EPLDPVRFIG NRSSGKQGYA VARVLAQRGA DVTLIAGNTA
240 GLIDPAGVEM VHIGSATQLR DAVSKHAPDA NVLVMAAAVA DFRPAHVAAA KIKKGASEPS
300 SIDLVRNDDV LAGAVRARAD GQLPNMRAIV GFAAETGDAN GDVLFHARAK LERKGCDLLV
360 VNAVGENRAF EVDHNDGWLL SADGTESALE HGSKTLMATR IVDSIAAFLK SQDG
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
20398
Deshayes C.,Perrodou E.,Gallien S.,Euphrasie D.,Schaeffer C.,Van-Dorsselaer A.,Poch O.,Lecompte O.,Reyrat J.-M.
Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?
Genome Biol.
8
R20.1-R20.9
2007
20399
Gallien S.,Perrodou E.,Carapito C.,Deshayes C.,Reyrat J.-M.,Van Dorsselaer A.,Poch O.,Schaeffer C.,Lecompte O.
Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol.
Genome Res.
19
128-135
2009
20401
Mendes V.,Green S.R.,Evans J.C.,Hess J.,Blaszczyk M.,Spry C.,Bryant O.,Cory-Wright J.,Chan D.S.,Torres P.H.M.,Wang Z.,Nahiyaan N.,O'Neill S.,Damerow S.,Post J.,Bayliss T.,Lynch S.L.,Coyne A.G.,Ray P.C.,Abell C.,Rhee K.Y.,Boshoff H.I.M.,Barry C.E. III,Mizrahi V.,Wyatt P.G.,Blundell T.L.
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site.
Nat. Commun.
12
143-143
2021
