Sequence of LOX15_RABIT

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
arachidonate 15-lipoxygenase
P12530
Oryctolagus cuniculus
663
75310
Reaction
arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MGVYRVCVST GASIYAGSKN KVELWLVGQH GEVELGSCLR PTRNKEEEFK VNVSKYLGSL
 60 LFVRLRKKHF LKEDAWFCNW ISVQALGAAE DKYWFPCYRW VVGDGVQSLP VGTGCTTVGD
120 PQGLFQKHRE QELEERRKLY QWGSWKEGLI LNVAGSKLTD LPVDERFLED KKIDFEASLA
180 WGLAELALKN SLNILAPWKT LDDFNRIFWC GRSKLARRVR DSWQEDSLFG YQFLNGANPM
240 LLRRSVQLPA RLVFPPGMEE LQAQLEKELK AGTLFEADFA LLDNIKANVI LYCQQYLAAP
300 LVMLKLQPDG KLMPMVIQLH LPKIGSSPPP LFLPTDPPMV WLLAKCWVRS SDFQVHELNS
360 HLLRGHLMAE VFTVATMRCL PSIHPVFKLI VPHLRYTLEI NVRARNGLVS DFGIFDQIMS
420 TGGGGHVQLL QQAGAFLTYR SFCPPDDLAD RGLLGVESSF YAQDALRLWE IISRYVQGIM
480 GLYYKTDEAV RDDLELQSWC REITEIGLQG AQKQGFPTSL QSVAQACHFV TMCIFTCTGQ
540 HSSIHLGQLD WFTWVPNAPC TMRLPPPTTK DATLETVMAT LPNLHQSSLQ MSIVWQLGRD
600 QPIMVPLGQH QEEYFSGPEP RAVLEKFREE LAIMDKEIEV RNEKLDIPYE YLRPSIVENS
660 VAI
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
303545
O'Prey J.,Chester J.,Thiele B.J.,Janetzki S.,Prehn S.,Fleming J.,Harrison P.R.
The promoter structure and complete sequence of the gene encoding the rabbit erythroid cell-specific 15-lipoxygenase.
Gene
84
493-499
1989
303546
Berger M.,Schwarz K.,Thiele H.,Reimann I.,Huth A.,Borngraeber S.,Kuehn H.,Thiele B.-J.
Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits.
J. Mol. Biol.
278
935-948
1998
303547
Fleming J.,Thiele B.J.,Chester J.,O'Prey J.,Janetzki S.,Aitken A.,Anton I.A.,Rapoport S.M.,Harrison P.R.
The complete sequence of the rabbit erythroid cell-specific 15-lipoxygenase mRNA: comparison of the predicted amino acid sequence of the erythrocyte lipoxygenase with other lipoxygenases.
Gene
79
181-188
1989
303548
Thiele B.J.,Fleming J.,Kasturi K.,O'Prey J.,Black E.,Chester J.,Rapoport S.M.,Harrison P.R.
Cloning of a rabbit erythroid-cell-specific lipoxygenase mRNA.
Gene
57
111-119
1987
303549
Thiele B.J.,Fleming J.,Chester J.,O'Prey J.,Prehn S.,Janetzki S.,Rapoport S.M.,Harrison P.R.
Structure of the mRNA and of the gene coding for the rabbit erythroid 15-lipoxygenase.
Biomed. Biochim. Acta
49
0-0
1990
303550
Brinckmann R.,Schnurr K.,Heydeck D.,Rosenbach T.,Kolde G.,Kuehn H.
Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme.
Blood
91
64-74
1998
303551
Gillmor S.A.,Villasenor A.,Fletterick R.,Sigal E.,Browner M.F.
The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity.
Nat. Struct. Biol.
4
1003-1009
1997