Sequence of GPT1_YEAST
EC Number:2.3.1.15
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glycerol-3-phosphate 1-O-acyltransferase
P32784
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
759
85694
Reaction
an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 1-acyl-sn-glycerol 3-phosphate
Other sequences found for EC No. 2.3.1.15
General information:
Sequence
0 MPAPKLTEKF ASSKSTQKTT NYSSIEAKSV KTSADQAYIY QEPSATKKIL YSIATWLLYN
60 IFHCFFREIR GRGSFKVPQQ GPVIFVAAPH ANQFVDPVIL MGEVKKSVNR RVSFLIAESS
120 LKQPPIGFLA SFFMAIGVVR PQDNLKPAEG TIRVDPTDYK RVIGHDTHFL TDCMPKGLIG
180 LPKSMGFGEI QSIESDTSLT LRKEFKMAKP EIKTALLTGT TYKYAAKVDQ SCVYHRVFEH
240 LAHNNCIGIF PEGGSHDRTN LLPLKAGVAI MALGCMDKHP DVNVKIVPCG MNYFHPHKFR
300 SRAVVEFGDP IEIPKELVAK YHNPETNRDA VKELLDTISK GLQSVTVTCS DYETLMVVQT
360 IRRLYMTQFS TKLPLPLIVE MNRRMVKGYE FYRNDPKIAD LTKDIMAYNA ALRHYNLPDH
420 LVEEAKVNFA KNLGLVFFRS IGLCILFSLA MPGIIMFSPV FILAKRISQE KARTALSKST
480 VKIKANDVIA TWKILIGMGF APLLYIFWSV LITYYLRHKP WNKIYVFSGS YISCVIVTYS
540 ALIVGDIGMD GFKSLRPLVL SLTSPKGLQK LQKDRRNLAE RIIEVVNNFG SELFPDFDSA
600 ALREEFDVID EEEEDRKTSE LNRRKMLRKQ KIKRQEKDSS SPIISQRDNH DAYEHHNQDS
660 DGVSLVNSDN SLSNIPLFSS TFHRKSESSL ASTSVAPSSS SEFEVENEIL EEKNGLASKI
720 AQAVLNKRIG ENTAREEEEE EEEEEEEEEE EEEGKEGDA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
299059
Matsushita M.,Nikawa J.
Isolation and characterization of a SCT1 gene which can suppress a choline-transport mutant of Saccharomyces cerevisiae.
J. Biochem.
117
447-451
1995
299060
Zheng Z.,Zou J.
The initial step of the glycerolipid pathway: identification of glycerol-3-phosphate / dihydroxyacetone phosphate dual substrate acyltransferases in Saccharomyces cerevisiae.
J. Biol. Chem.
276
41710-41716
2001
299061
Skala J.,van Dyck L.,Purnelle B.,Goffeau A.
The sequence of an 8 kb segment on the left arm of chromosome II from Saccharomyces cerevisiae identifies five new open reading frames of unknown functions, two tRNA genes and two transposable elements.
Yeast
8
777-785
1992
299062
Feldmann H.,Aigle M.,Aljinovic G.,Andre B.,Baclet M.C.,Barthe C.,Baur A.,Becam A.-M.,Biteau N.,Boles E.,Brandt T.,Brendel M.,Brueckner M.,Bussereau F.,Christiansen C.,Contreras R.,Crouzet M.,Cziepluch C.,Demolis N.,Delaveau T.,Doignon F.,Domdey H.,Duesterhus S.,Dubois E.,Dujon B.,El Bakkoury M.,Entian K.-D.,Feuermann M.,Fiers W.,Fobo G.M.,Fritz C.,Gassenhuber J.,Glansdorff N.,Goffeau A.,Grivell L.A.,de Haan M.,Hein C.,Herbert C.J.,Hollenberg C.P.,Holmstroem K.,Jacq C.,Jacquet M.,Jauniaux J.-C.,Jonniaux J.-L.,Kallesoee T.,Kiesau P.,Kirchrath L.,Koetter P.,Korol S.,Liebl S.,Logghe M.,Lohan A.J.E.,Louis E.J.,Li Z.Y.,Maat M.J.,Mallet L.,Mannhaupt G.,Messenguy F.,Miosga T.,Molemans F.,Mueller S.,Nasr F.,Obermaier B.,Perea J.,Pierard A.,Piravandi E.,Pohl F.M.,Pohl T.M.,Potier S.,Proft M.,Purnelle B.,Ramezani Rad M.,Rieger M.,Rose M.,Schaaff-Gerstenschlaeger I.,Scherens B.,Schwarzlose C.,Skala J.,Slonimski P.P.,Smits P.H.M.,Souciet J.-L.,Steensma H.Y.,Stucka R.,Urrestarazu L.A.,van der Aart Q.J.M.,Van Dyck L.,Vassarotti A.,Vetter I.,Vierendeels F.,Vissers S.,Wagner G.,de Wergifosse P.,Wolfe K.H.,Zagulski M.,Zimmermann F.K.,Mewes H.-W.,Kleine K.
Complete DNA sequence of yeast chromosome II.
EMBO J.
13
5795-5809
1994
299063
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
299064
Delaveau T.,Jacq C.,Perea J.
Sequence of a 12.7 kb segment of yeast chromosome II identifies a PDR-like gene and several new open reading frames.
Yeast
8
761-768
1992
299065
Zaremberg V.,McMaster C.R.
Differential partitioning of lipids metabolized by separate yeast glycerol-3-phosphate acyltransferases reveals that phospholipase D generation of phosphatidic acid mediates sensitivity to choline-containing lysolipids and drugs.
J. Biol. Chem.
277
39035-39044
2002
299066
Huh W.-K.,Falvo J.V.,Gerke L.C.,Carroll A.S.,Howson R.W.,Weissman J.S.,O'Shea E.K.
Global analysis of protein localization in budding yeast.
Nature
425
686-691
2003
299067
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
299068
Albuquerque C.P.,Smolka M.B.,Payne S.H.,Bafna V.,Eng J.,Zhou H.
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
Mol. Cell. Proteomics
7
1389-1396
2008
299069
Bratschi M.W.,Burrowes D.P.,Kulaga A.,Cheung J.F.,Alvarez A.L.,Kearley J.,Zaremberg V.
Glycerol-3-phosphate acyltransferases gat1p and gat2p are microsomal phosphoproteins with differential contributions to polarized cell growth.
Eukaryot. Cell
8
1184-1196
2009
299070
Holt L.J.,Tuch B.B.,Villen J.,Johnson A.D.,Gygi S.P.,Morgan D.O.
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
Science
325
1682-1686
2009
299071
De Smet C.H.,Vittone E.,Scherer M.,Houweling M.,Liebisch G.,Brouwers J.F.,de Kroon A.I.
The yeast acyltransferase Sct1p regulates fatty acid desaturation by competing with the desaturase Ole1p.
Mol. Biol. Cell
23
1146-1156
2012
299072
Debelyy M.O.,Waridel P.,Quadroni M.,Schneiter R.,Conzelmann A.
Chemical crosslinking and mass spectrometry to elucidate the topology of integral membrane proteins.
PLoS ONE
12
0-0
2017
