Sequence of END8B_MYCTU
EC Number:4.2.99.18
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
DNA-(apurinic or apyrimidinic site) lyase
P9WNC1
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
255
28526
Reaction
the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Other sequences found for EC No. 4.2.99.18
General information:
Sequence
0 MPEGDTVWHT AATLRRHLAG RTLTRCDIRV PRFAAVDLTG EVVDEVISRG KHLFIRTGTA
60 SIHSHLQMDG SWRVGNRPVR VDHRARIILE ANQQEQAIRV VGVDLGLLEV IDRHNDGAVV
120 AHLGPDLLAD DWDPQRAAAN LIVAPDRPIA EALLDQRVLA GIGNVYCNEL CFVSGVLPTA
180 PVSAVADPRR LVTRARDMLW VNRFRWNRCT TGDTRAGRRL WVYGRAGQGC RRCGTLIAYD
240 TTDERVRYWC PACQR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
30181
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
30182
Sidorenko V.S.,Rot M.A.,Filipenko M.L.,Nevinsky G.A.,Zharkov D.O.
Novel DNA glycosylases from Mycobacterium tuberculosis.
Biochemistry (Mosc.)
73
442-450
2008
30183
Guo Y.,Bandaru V.,Jaruga P.,Zhao X.,Burrows C.J.,Iwai S.,Dizdaroglu M.,Bond J.P.,Wallace S.S.
The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts.
DNA Repair
9
177-190
2010
30184
Kurthkoti K.,Varshney U.
Base excision and nucleotide excision repair pathways in mycobacteria.
Tuberculosis
91
533-543
2011
