Sequence of DOT1_NEUCR
EC Number:2.1.1.360
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
[histone H3]-lysine79 N-trimethyltransferase
Q7SB74
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
531
59294
Reaction
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine79 = 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine79
Other sequences found for EC No. 2.1.1.360
General information:
Sequence
0 MSIFNQKSKF KIKTEIRTVR ETVERPKLKA STSSSSIPTT GSSQHSNVRI AGAGSSLSRA
60 SSTPRLNGTS HTTSTSSSAR ASLTKVTTIP TARRIQSASP IPSINGDGRS SRKRRAIKAS
120 SRSPISPHFS EDSDSDSNGD ENWEDNLDAR KRRKRVHDER PVDVNRKLRH PKIWKGEEAD
180 QVERIPGPAI IHAAKVASLE HKCKPALGLK NEEVAVRLQY PGARYPERYE LVEGKDKIDA
240 VKDIEKVVQL AASTYLTDEE GKIFLDHQTG ILRKLVKSKN RSDGPGFKAA LREYNDEFLK
300 LMRKGVIVRN LDKMHGIPRE LVDFILDQVY DRTVAPRVEL LAKYQNGSDN VYGELNHPFI
360 SDILERTNLT SDKVFVDLGS GVGNVTLQAA LEIGCESWGC EMMENACNLA EAQYDEFLAR
420 CRLWGVKPGK VRLERGDFRK NEKILEVLKR ADVVLVNNQA FTSQLNDNLV SMFLDLKIGC
480 KIISLKTFVH DNKNAENDVA TSILDVEHLT YPEGYVSWTG ASGTYCISTR R
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
26682
Galagan J.E.,Calvo S.E.,Borkovich K.A.,Selker E.U.,Read N.D.,Jaffe D.B.,FitzHugh W.,Ma L.-J.,Smirnov S.,Purcell S.,Rehman B.,Elkins T.,Engels R.,Wang S.,Nielsen C.B.,Butler J.,Endrizzi M.,Qui D.,Ianakiev P.,Bell-Pedersen D.,Nelson M.A.,Werner-Washburne M.,Selitrennikoff C.P.,Kinsey J.A.,Braun E.L.,Zelter A.,Schulte U.,Kothe G.O.,Jedd G.,Mewes H.-W.,Staben C.,Marcotte E.,Greenberg D.,Roy A.,Foley K.,Naylor J.,Stange-Thomann N.,Barrett R.,Gnerre S.,Kamal M.,Kamvysselis M.,Mauceli E.W.,Bielke C.,Rudd S.,Frishman D.,Krystofova S.,Rasmussen C.,Metzenberg R.L.,Perkins D.D.,Kroken S.,Cogoni C.,Macino G.,Catcheside D.E.A.,Li W.,Pratt R.J.,Osmani S.A.,DeSouza C.P.C.,Glass N.L.,Orbach M.J.,Berglund J.A.,Voelker R.,Yarden O.,Plamann M.,Seiler S.,Dunlap J.C.,Radford A.,Aramayo R.,Natvig D.O.,Alex L.A.,Mannhaupt G.,Ebbole D.J.,Freitag M.,Paulsen I.,Sachs M.S.,Lander E.S.,Nusbaum C.,Birren B.W.
The genome sequence of the filamentous fungus Neurospora crassa.
Nature
422
859-868
2003
