Sequence of DOT1_CRYNJ
EC Number:2.1.1.360
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
[histone H3]-lysine79 N-trimethyltransferase
P0CN14
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
644
71286
Reaction
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine79 = 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine79
Other sequences found for EC No. 2.1.1.360
General information:
Sequence
0 MFSFFGDESK LPASTVMVSR MTVKKQAVAR QQSSGPMAGP SKPSNVTPKH SHGSLKGTPR
60 SASEKGTPKQ GPSSSSKSTS KVKQEERIRL STIPRTPASS SSPGRLKRKT PKVQVVESES
120 SSGSESSDGA LDSKPKRPKV TRKETGIDMT PLPGEEVVGR RVFCWDKVDM RGEWGRGWAG
180 FVGCDEVVRG NVQGWANGGG GDGSKNLGKY RAFFPQEGFD RDGDFLPSVE VLYPAKGCRE
240 KFVLMVPSSD REFNPIGELR NTLRLILEHY IPPSHRHIFG TLAESLDISN PLSSLPSRMT
300 TPLPNSLVTP PPDPASPSPA FAFEISATST PAPSTERQET IADLIRKSLA PNRRDGPLFV
360 TAIERYNSAM QAIQEDGTLQ QWLDEGMNGG KGIKVREWAA LVDFVHDQAY SRVVGGYSHE
420 LEHHPKHPEE VSKAISGKED AYGELRHAFM SKIIEQTKLG PDSVFVDLGS GVGNCVLQAS
480 LQAGSRSYGF ELLPVPAHCA RLQVREVQRR WAMWALKGNL DVEVHEGDFR VHKEVGRRLR
540 EADVVLVNNE VFPSSLNMDL ADMFLDLKEG AKIVSLKPFV PEGFRMNESN CDSFAAILRS
600 TQHDYYRDWV SWKGEWGNYY VAVIDRSRRI KFEESMKGRA SRRR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
26674
Loftus B.J.,Fung E.,Roncaglia P.,Rowley D.,Amedeo P.,Bruno D.,Vamathevan J.,Miranda M.,Anderson I.J.,Fraser J.A.,Allen J.E.,Bosdet I.E.,Brent M.R.,Chiu R.,Doering T.L.,Donlin M.J.,D'Souza C.A.,Fox D.S.,Grinberg V.,Fu J.,Fukushima M.,Haas B.J.,Huang J.C.,Janbon G.,Jones S.J.M.,Koo H.L.,Krzywinski M.I.,Kwon-Chung K.J.,Lengeler K.B.,Maiti R.,Marra M.A.,Marra R.E.,Mathewson C.A.,Mitchell T.G.,Pertea M.,Riggs F.R.,Salzberg S.L.,Schein J.E.,Shvartsbeyn A.,Shin H.,Shumway M.,Specht C.A.,Suh B.B.,Tenney A.,Utterback T.R.,Wickes B.L.,Wortman J.R.,Wye N.H.,Kronstad J.W.,Lodge J.K.,Heitman J.,Davis R.W.,Fraser C.M.,Hyman R.W.
The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans.
Science
307
1321-1324
2005
