Sequence of ATNF_EMENI
EC Number:2.3.1.86
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
fatty-acyl-CoA synthase system
Q5AV00
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
1659
181995
Reaction
acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoyl-CoA + 7 CoA + 7 CO2 + 14 NADP+ + 7 H2O
Other sequences found for EC No. 2.3.1.86
General information:
Sequence
0 MVAAQDDGAQ RKLAHTLLLE LMSYQFASPV RWIETQDVVL GQYRAERIIE IGPAATLTNM
60 IKQTVQSKFL HSDRASLLQR QLLASEKQGK DIYYEDDGVG IGTGAEAPAP SAKTQAQASG
120 GAGTIAGAGS STAPVTAPPA PAAAKAVPAG GMQAIEDRQA QAFEIVRTLL SRILKIALTD
180 VVGTQSIKSL SGGRSTLENE IIGDLASEFG SLPDRAEDLT VNDLSAALQK TFTGQMRKVI
240 LKMLHAMFAS KMPGQFTVAT ARTYLHSRWG LGSGRQDSVL LLAIAQQPGS RLKEEAEARS
300 FFDGLVQFYA DEHGLTLGAN SGAADETSGL GGGLVMDQKT LAALTGGQQE LSKALLKIYA
360 KHLDIDLDGD RRALHDLQAT VEKDLRLALD QIHQELGEDF TDGVQPVFSA RKARRFDSAW
420 SWALQDLLQL YYEVSRTGGE TEVDLAAKRC KHIEDAADPR LLDVLQRIVG RFEQQPVLSS
480 MFTQLAQRCR DSLLHGPRYL ARPDQQGPRT TISAEGDITY TEQERAEPVP LADLVYLPKS
540 TEAAPLEPFL HLKQRTGGSS AWTYSHDLTE QYRAVLEQAT TVGESFAGRS VLITGAGVGS
600 IGAEVLKGLL AGGARVIVTT SRFSSSVVRK YQDLYTQVGS RGSELVVVPF NQASVQDVTA
660 LVNYIYDAQG GLHWDLDHIL PFAAMPENGR TIEKIDPHSE LAHRTMMVNT LRLLGAVKAR
720 KEAQGSRTRP TQVILPLSPN HGVFGGDGLY SESKLGLEAL FNRWHSEDWS DYLSVCGAVI
780 GWTRGTGLMS GNNLVAEGIE ELGCRTFSQQ EMAQCLLCLM FNTMCSLCEE APLYADLSGR
840 MGAVQNLRQK VQELRTEINE TANTRRALLE ELAMEARCSE GPTPTIDSEP AKATATPTLT
900 AHVRLDFPPT VDYNQEIKPL TADLQGMVDL DRVVVVTGFG EIGPWGNART RWEMEAYGEF
960 SLEGCVEMAW LMGLIRYENS SSPGWVDAKT NERVHDHEVK HKYEEHILSH TGIRLIEPDR
1020 FGANYHPEHK QLLHEVLIQE DFPELEVPEA TAQQMKLEHG NKVDIIPDPE GGDQCRVVLK
1080 KGAKLMVPKA LRLDRMVIGQ IPTGWDARKY GIPEDVISQV DPVTLYMLAC SIEALLSSGI
1140 TDPYEIYRYI HVSEAGNCVG SSLGGFNSLQ QMYRGRYMEK EVQKDILQET FVNTIGAWMN
1200 MLLMSSAGPI RTPVGACATA IESVELGYDT LISGKAKFCF VGGGDDFGEE VLYEFANMKA
1260 TANTVDEFEQ GREASEMSRP AASTRNGFME SHGCGVQILT TARLAIEMGL PVRGVIAFVE
1320 TSSDKASRSV PAPGRGILSK AREVRSSSPS SSLISSPLLN ISNRRKRLDF RKKQIEFARE
1380 TALEELQLEI AHVEESEVED YIRERTAQIN AEAQKDLRNA QYHLGNAFWQ NDPSIAPLRG
1440 ALAVWGLTID DLDVASFHGT STKLNEKNEC SLIQAQLSHL GRAKGNVILG VFQKYLTGHP
1500 KGAAGAWMLN GALQILDTGI VPGNRNLDNV EAELQKNEQI AFLNRSLDTG RGSMRAVSVT
1560 SFGFGQKGAQ TIVVHPKYLF ATLEEQEYEE YLDKRAKRQK KADSFFYRGL ASNRLFELKT
1620 APPWAPQKEL ETLLDPTPPQ TNVDDRVARS IVQQESAEP
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
267727
Galagan J.E.,Calvo S.E.,Cuomo C.,Ma L.-J.,Wortman J.R.,Batzoglou S.,Lee S.-I.,Bastuerkmen M.,Spevak C.C.,Clutterbuck J.,Kapitonov V.,Jurka J.,Scazzocchio C.,Farman M.L.,Butler J.,Purcell S.,Harris S.,Braus G.H.,Draht O.,Busch S.,D'Enfert C.,Bouchier C.,Goldman G.H.,Bell-Pedersen D.,Griffiths-Jones S.,Doonan J.H.,Yu J.,Vienken K.,Pain A.,Freitag M.,Selker E.U.,Archer D.B.,Penalva M.A.,Oakley B.R.,Momany M.,Tanaka T.,Kumagai T.,Asai K.,Machida M.,Nierman W.C.,Denning D.W.,Caddick M.X.,Hynes M.,Paoletti M.,Fischer R.,Miller B.L.,Dyer P.S.,Sachs M.S.,Osmani S.A.,Birren B.W.
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.
Nature
438
1105-1115
2005
267728
Wortman J.R.,Gilsenan J.M.,Joardar V.,Deegan J.,Clutterbuck J.,Andersen M.R.,Archer D.,Bencina M.,Braus G.,Coutinho P.,von Dohren H.,Doonan J.,Driessen A.J.,Durek P.,Espeso E.,Fekete E.,Flipphi M.,Estrada C.G.,Geysens S.,Goldman G.,de Groot P.W.,Hansen K.,Harris S.D.,Heinekamp T.,Helmstaedt K.,Henrissat B.,Hofmann G.,Homan T.,Horio T.,Horiuchi H.,James S.,Jones M.,Karaffa L.,Karanyi Z.,Kato M.,Keller N.,Kelly D.E.,Kiel J.A.,Kim J.M.,van der Klei I.J.,Klis F.M.,Kovalchuk A.,Krasevec N.,Kubicek C.P.,Liu B.,Maccabe A.,Meyer V.,Mirabito P.,Miskei M.,Mos M.,Mullins J.,Nelson D.R.,Nielsen J.,Oakley B.R.,Osmani S.A.,Pakula T.,Paszewski A.,Paulsen I.,Pilsyk S.,Pocsi I.,Punt P.J.,Ram A.F.,Ren Q.,Robellet X.,Robson G.,Seiboth B.,van Solingen P.,Specht T.,Sun J.,Taheri-Talesh N.,Takeshita N.,Ussery D.,vanKuyk P.A.,Visser H.,van de Vondervoort P.J.,de Vries R.P.,Walton J.,Xiang X.,Xiong Y.,Zeng A.P.,Brandt B.W.,Cornell M.J.,van den Hondel C.A.,Visser J.,Oliver S.G.,Turner G.
The 2008 update of the Aspergillus nidulans genome annotation: a community effort.
Fungal Genet. Biol.
46
0-13
2009
267729
Andersen M.R.,Nielsen J.B.,Klitgaard A.,Petersen L.M.,Zachariasen M.,Hansen T.J.,Blicher L.H.,Gotfredsen C.H.,Larsen T.O.,Nielsen K.F.,Mortensen U.H.
Accurate prediction of secondary metabolite gene clusters in filamentous fungi.
Proc. Natl. Acad. Sci. U.S.A.
110
0-0
2013
267730
Henke M.T.,Soukup A.A.,Goering A.W.,McClure R.A.,Thomson R.J.,Keller N.P.,Kelleher N.L.
New aspercryptins, lipopeptide natural products, revealed by HDAC inhibition in Aspergillus nidulans.
ACS Chem. Biol.
11
2117-2123
2016
267731
Chiang Y.M.,Ahuja M.,Oakley C.E.,Entwistle R.,Asokan A.,Zutz C.,Wang C.C.,Oakley B.R.
Development of genetic dereplication strains in Aspergillus nidulans results in the discovery of aspercryptin.
Angew. Chem. Int. Ed.
55
1662-1665
2016
