Sequence of AKT1_CAEEL
EC Number:2.7.11.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.1
General information:
Sequence
0 MSMTSLSTKS RRQEDVVIEG WLHKKGEHIR NWRPRYFMIF NDGALLGFRA KPKEGQPFPE
60 PLNDFMIKDA ATMLFEKPRP NMFMVRCLQW TTVIERTFYA ESAEVRQRWI HAIESISKKY
120 KGTNANPQEE LMETNQQPKI DEDSEFAGAA HAIMGQPSSG HGDNCSIDFR ASMISIADTS
180 EAAKRDKITM EDFDFLKVLG KGTFGKVILC KEKRTQKLYA IKILKKDVII AREEVAHTLT
240 ENRVLQRCKH PFLTELKYSF QEQHYLCFVM QFANGGELFT HVRKCGTFSE PRARFYGAEI
300 VLALGYLHRC DIVYRDMKLE NLLLDKDGHI KIADFGLCKE EISFGDKTST FCGTPEYLAP
360 EVLDDHDYGR CVDWWGVGVV MYEMMCGRLP FYSKDHNKLF ELIMAGDLRF PSKLSQEART
420 LLTGLLVKDP TQRLGGGPED ALEICRADFF RTVDWEATYR KEIEPPYKPN VQSETDTSYF
480 DNEFTSQPVQ LTPPSRSGAL ATVDEQEEMQ SNFTQFSFHN VMGSINRIHE ASEDNEDYDM
540 G
Download this sequence
in fasta formatDownload all sequences for 2.7.11.1
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
262820
Paradis S.,Ruvkun G.
Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor.
Genes Dev.
12
2488-2498
1998
262821
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
262822
Paradis S.,Ailion M.,Toker A.,Thomas J.H.,Ruvkun G.
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans.
Genes Dev.
13
1438-1452
1999
262823
Henderson S.T.,Johnson T.E.
daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans.
Curr. Biol.
11
1975-1980
2001
262824
Lin K.,Hsin H.,Libina N.,Kenyon C.
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling.
Nat. Genet.
28
139-145
2001
262825
Hertweck M.,Goebel C.,Baumeister R.
C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span.
Dev. Cell
6
577-588
2004
262826
Tomioka M.,Adachi T.,Suzuki H.,Kunitomo H.,Schafer W.R.,Iino Y.
The insulin/PI 3-kinase pathway regulates salt chemotaxis learning in Caenorhabditis elegans.
Neuron
51
613-625
2006
262827
Evans E.A.,Chen W.C.,Tan M.-W.
The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans.
Aging Cell
7
879-893
2008
262828
Tullet J.M.,Hertweck M.,An J.H.,Baker J.,Hwang J.Y.,Liu S.,Oliveira R.P.,Baumeister R.,Blackwell T.K.
Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans.
Cell
132
1025-1038
2008
262829
Shen X.,Valencia C.A.,Gao W.,Cotten S.W.,Dong B.,Huang B.C.,Liu R.
Ca(2+)/Calmodulin-binding proteins from the C. elegans proteome.
Cell Calcium
43
444-456
2008
262830
Padmanabhan S.,Mukhopadhyay A.,Narasimhan S.D.,Tesz G.,Czech M.P.,Tissenbaum H.A.
A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation.
Cell
136
939-951
2009
262831
Nakagawa A.,Sullivan K.D.,Xue D.
Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway.
Nat. Struct. Mol. Biol.
21
1082-1090
2014
262832
Peymen K.,Watteyne J.,Borghgraef C.,Van Sinay E.,Beets I.,Schoofs L.
Myoinhibitory peptide signaling modulates aversive gustatory learning in Caenorhabditis elegans.
PLoS Genet.
15
0-0
2019
