Sequence of UPPS_GIAIC
EC Number:2.5.1.31
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
A8B1Z2
Giardia intestinalis (strain ATCC 50803 / WB clone C6)
265
29968
Reaction
(2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = 8 diphosphate + ditrans,octacis-undecaprenyl diphosphate
Other sequences found for EC No. 2.5.1.31
General information:
Sequence
0 MIPMHVAVIM DGNGRWARKQ LQERTFGHEQ GVSVLESIVD ECINCGIRFL TVYAFSTENW
60 SRPPTEVSFL FELLSAAIQR VRTTYRERNV KVQFCGERTT QIPETVIAAM NCIEQDTAAC
120 TGLILSVCFN YGGHTEIAQA CRSVLADCLE GDAVENIKTR LQMPIEQFIQ QIDTHLYANL
180 PPVDLLIRTG CEKRLSNFLP WHLAYAEIIF SDLLWPEFSV RAFKDCLDEF ASRTRRFGGV
240 QLSPMTGVYS DTHPHSSTNA LSNHD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
247667
Morrison H.G.,McArthur A.G.,Gillin F.D.,Aley S.B.,Adam R.D.,Olsen G.J.,Best A.A.,Cande W.Z.,Chen F.,Cipriano M.J.,Davids B.J.,Dawson S.C.,Elmendorf H.G.,Hehl A.B.,Holder M.E.,Huse S.M.,Kim U.U.,Lasek-Nesselquist E.,Manning G.,Nigam A.,Nixon J.E.J.,Palm D.,Passamaneck N.E.,Prabhu A.,Reich C.I.,Reiner D.S.,Samuelson J.,Svard S.G.,Sogin M.L.
Genomic minimalism in the early diverging intestinal parasite Giardia lamblia.
Science
317
1921-1926
2007
247668
Grabinska K.A.,Cui J.,Chatterjee A.,Guan Z.,Raetz C.R.,Robbins P.W.,Samuelson J.
Molecular characterization of the cis-prenyltransferase of Giardia lamblia.
Glycobiology
20
824-832
2010
247669
Park E.J.,Grabinska K.A.,Guan Z.,Stranecky V.,Hartmannova H.,Hodanova K.,Baresova V.,Sovova J.,Jozsef L.,Ondruskova N.,Hansikova H.,Honzik T.,Zeman J.,Hulkova H.,Wen R.,Kmoch S.,Sessa W.C.
Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation.
Cell Metab.
20
448-457
2014
247670
Grabinska K.A.,Edani B.H.,Park E.J.,Kraehling J.R.,Sessa W.C.
A conserved C-terminal RXG motif in the NgBR subunit of cis-prenyltransferase is critical for prenyltransferase activity.
J. Biol. Chem.
292
17351-17361
2017
