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Sequence of UDB17_RAT

EC Number:2.4.1.17

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glucuronosyltransferase
P08542
Rattus norvegicus
530
60525
Reaction
UDP-alpha-D-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside
Other sequences found for EC No. 2.4.1.17

General information:

Sequence
show sequence in normal format
>P08542|glucuronosyltransferase|EC 2.4.1.17|Rattus norvegicus|Swiss-Prot
MPGKWISALLLLQISCCFQSGNCGKVLVWPMEFSHWMNIKTILDELVQRGHEVTVLKPSA
YYVLDPKKSPDLKFETFPTSVSKDELENYFIKLVDVWTYELQRDTCLSYSPLLQNMIDGF
SDYYLSLCKDTVSNKQLMAKLQESKFDVLLSDPVAACGELIAEVLHIPFLYSLRFSPGYK
IEKSSGRFILPPSYVPVILSGMGGPMTFIDRVKNMICTLYFDFWFHMFNAKKWDPFYSEI
LGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCRPPKPLPKDMEDFVQSS
GEHGVVVFSLGSMVSSMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYKWLPQ
NDLLGHPKTKAFVTHSGANGVYEAIYHGIPMVGIPMFGEQHDNIAHMVAKGAAVTLNIRT
MSKSDLFNALKEIINNPFYKKNAVWLSTIHHDQPMKPLDKAVFWIEFVMRHKGAKHLRPL
GHDLPWYQYHSLDVIGFLLTCSAVIAVLTVKCFLFIYRLFVKKEKKMKNE
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
246992
McKenzie P.I.
Rat liver UDP-glucuronosyltransferase. Identification of cDNAs encoding two enzymes which glucuronidate testosterone, dihydrotestosterone, and beta-estradiol.
J. Biol. Chem.
262
9744-9749
1987
246993
Harding D.,Wilson S.M.,Jackson M.R.,Burchell B.,Green M.D.,Tephly T.R.
Nucleotide and deduced amino acid sequence of rat liver 17 beta-hydroxysteroid UDP-glucuronosyltransferase.
Nucleic Acids Res.
15
3936-3936
1987
246994
McKenzie P.I.
The cDNA sequence and expression of a variant 17 beta-hydroxysteroid UDP-glucuronosyltransferase.
J. Biol. Chem.
265
8699-8703
1990
246995
Itaeaho K.,Mackenzie P.I.,Ikushiro S.,Miners J.O.,Finel M.
The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.
Drug Metab. Dispos.
36
2307-2315
2008