Sequence of TRXR_PLAF7
EC Number:1.8.1.9
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+
Other sequences found for EC No. 1.8.1.9
General information:
Sequence
0 MNNVISFIGN SSNKYFQINQ LHFIRIINKN IHSKNNLINS NSSYNVFYNK YFIKNTFQNK
60 NKLSSIYSKL NFSIKNMCKD KNEKKNYEHV NANEKNGYLA SEKNELTKNK VEEHTYDYDY
120 VVIGGGPGGM ASAKEAAAHG ARVLLFDYVK PSSQGTKWGI GGTCVNVGCV PKKLMHYAGH
180 MGSIFKLDSK AYGWKFDNLK HDWKKLVTTV QSHIRSLNFS YMTGLRSSKV KYINGLAKLK
240 DKNTVSYYLK GDLSKEETVT GKYILIATGC RPHIPDDVEG AKELSITSDD IFSLKKDPGK
300 TLVVGASYVA LECSGFLNSL GYDVTVAVRS IVLRGFDQQC AVKVKLYMEE QGVMFKNGIL
360 PKKLTKMDDK ILVEFSDKTS ELYDTVLYAI GRKGDIDGLN LESLNMNVNK SNNKIIADHL
420 SCTNIPSIFA VGDVAENVPE LAPVAIKAGE ILARRLFKDS DEIMDYSYIP TSIYTPIEYG
480 ACGYSEEKAY ELYGKSNVEV FLQEFNNLEI SAVHRQKHIR AQKDEYDLDV SSTCLAKLVC
540 LKNEDNRVIG FHYVGPNAGE VTQGMALALR LKVKKKDFDN CIGIHPTDAE SFMNLFVTIS
600 SGLSYAAKGG CGGGKCG
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
244883
Nickel C.,Rahlfs S.,Deponte M.,Koncarevic S.,Becker K.
Thioredoxin networks in the malarial parasite Plasmodium falciparum.
Antioxid. Redox Signal.
8
1227-1239
2006
244884
Gardner M.J.,Hall N.,Fung E.,White O.,Berriman M.,Hyman R.W.,Carlton J.M.,Pain A.,Nelson K.E.,Bowman S.,Paulsen I.T.,James K.D.,Eisen J.A.,Rutherford K.M.,Salzberg S.L.,Craig A.,Kyes S.,Chan M.-S.,Nene V.,Shallom S.J.,Suh B.,Peterson J.,Angiuoli S.,Pertea M.,Allen J.,Selengut J.,Haft D.,Mather M.W.,Vaidya A.B.,Martin D.M.A.,Fairlamb A.H.,Fraunholz M.J.,Roos D.S.,Ralph S.A.,McFadden G.I.,Cummings L.M.,Subramanian G.M.,Mungall C.,Venter J.C.,Carucci D.J.,Hoffman S.L.,Newbold C.,Davis R.W.,Fraser C.M.,Barrell B.G.
Genome sequence of the human malaria parasite Plasmodium falciparum.
Nature
419
498-511
2002
244885
Hall N.,Pain A.,Berriman M.,Churcher C.M.,Harris B.,Harris D.,Mungall K.L.,Bowman S.,Atkin R.,Baker S.,Barron A.,Brooks K.,Buckee C.O.,Burrows C.,Cherevach I.,Chillingworth C.,Chillingworth T.,Christodoulou Z.,Clark L.,Clark R.,Corton C.,Cronin A.,Davies R.M.,Davis P.,Dear P.,Dearden F.,Doggett J.,Feltwell T.,Goble A.,Goodhead I.,Gwilliam R.,Hamlin N.,Hance Z.,Harper D.,Hauser H.,Hornsby T.,Holroyd S.,Horrocks P.,Humphray S.,Jagels K.,James K.D.,Johnson D.,Kerhornou A.,Knights A.,Konfortov B.,Kyes S.,Larke N.,Lawson D.,Lennard N.,Line A.,Maddison M.,Mclean J.,Mooney P.,Moule S.,Murphy L.,Oliver K.,Ormond D.,Price C.,Quail M.A.,Rabbinowitsch E.,Rajandream M.A.,Rutter S.,Rutherford K.M.,Sanders M.,Simmonds M.,Seeger K.,Sharp S.,Smith R.,Squares R.,Squares S.,Stevens K.,Taylor K.,Tivey A.,Unwin L.,Whitehead S.,Woodward J.R.,Sulston J.E.,Craig A.,Newbold C.,Barrell B.G.
Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.
Nature
419
527-531
2002
244886
Gilberger T.W.,Walter R.D.,Mueller S.
Identification and characterization of the functional amino acids at the active site of the large thioredoxin reductase from Plasmodium falciparum.
J. Biol. Chem.
272
29584-29589
1997
244887
Kanzok S.M.,Schirmer R.H.,Turbachova I.,Iozef R.,Becker K.
The thioredoxin system of the malaria parasite Plasmodium falciparum. Glutathione reduction revisited.
J. Biol. Chem.
275
40180-40186
2000
244888
Kehr S.,Sturm N.,Rahlfs S.,Przyborski J.M.,Becker K.
Compartmentation of redox metabolism in malaria parasites.
PLoS Pathog.
6
0-0
2010
244889
Boumis G.,Giardina G.,Angelucci F.,Bellelli A.,Brunori M.,Dimastrogiovanni D.,Saccoccia F.,Miele A.E.
Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target.
Biochem. Biophys. Res. Commun.
425
806-811
2012
244890
Fritz-Wolf K.,Jortzik E.,Stumpf M.,Preuss J.,Iozef R.,Rahlfs S.,Becker K.
Crystal structure of the Plasmodium falciparum thioredoxin reductase-thioredoxin complex.
J. Mol. Biol.
425
3446-3460
2013
