Sequence of RIFK_AMYMS
EC Number:4.2.1.144
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
5-amino-5-deoxy-3-dehydroshikimate = 3-amino-5-hydroxybenzoate + H2O
Other sequences found for EC No. 4.2.1.144
General information:
Sequence
0 MNARKAPEFP AWPQYDDAER NGLVRALEQG QWWRMGGDEV NSFEREFAAH HGAAHALAVT
60 NGTHALELAL QVMGVGPGTE VIVPAFTFIS SSQAAQRLGA VTVPVDVDAA TYNLDPEAVA
120 AAVTPRTKVI MPVHMAGLMA DMDALAKISA DTGVPLLQDA AHAHGARWQG KRVGELDSIA
180 TFSFQNGKLM TAGEGGAVVF PDGETEKYET AFLRHSCGRP RDDRRYFHKI AGSNMRLNEF
240 SASVLRAQLA RLDEQIAVRD ERWTLLSRLL GAIDGVVPQG GDVRADRNSH YMAMFRIPGL
300 TEERRNALVD RLVEAGLPAF AAFRAIYRTD AFWELGAPDE SVDAIARRCP NTDAISSDCV
360 WLHHRVLLAG EPELHATAEI IADAVARA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
217011
August P.R.,Tang L.,Yoon Y.J.,Ning S.,Mueller R.,Yu T.W.,Taylor M.,Hoffmann D.,Kim C.G.,Zhang X.,Hutchinson C.R.,Floss H.G.
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.
Chem. Biol.
5
69-79
1998
217012
Kim C.G.,Yu T.W.,Fryhle C.B.,Handa S.,Floss H.G.
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.
J. Biol. Chem.
273
6030-6040
1998
217013
Verma M.,Kaur J.,Kumar M.,Kumari K.,Saxena A.,Anand S.,Nigam A.,Ravi V.,Raghuvanshi S.,Khurana P.,Tyagi A.K.,Khurana J.P.,Lal R.
Whole genome sequence of the rifamycin B-producing strain Amycolatopsis mediterranei S699.
J. Bacteriol.
193
5562-5563
2011
217014
Tang B.,Zhao W.,Zheng H.,Zhuo Y.,Zhang L.,Zhao G.P.
Complete genome sequence of Amycolatopsis mediterranei S699 based on de novo assembly via a combinatorial sequencing strategy.
J. Bacteriol.
194
5699-5700
2012
217015
Yu T.W.,Muller R.,Muller M.,Zhang X.,Draeger G.,Kim C.G.,Leistner E.,Floss H.G.
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.
J. Biol. Chem.
276
12546-12555
2001
217016
Floss H.G.,Yu T.W.,Arakawa K.
The biosynthesis of 3-amino-5-hydroxybenzoic acid (AHBA), the precursor of mC7N units in ansamycin and mitomycin antibiotics: a review.
J. Antibiot.
64
35-44
2011
217017
Eads J.C.,Beeby M.,Scapin G.,Yu T.W.,Floss H.G.
Crystal structure of 3-amino-5-hydroxybenzoic acid (AHBA) synthase.
Biochemistry
38
9840-9849
1999
