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Sequence of PHLB_MYCTU

EC Number:3.1.4.3

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
phospholipase C
P9WIB3
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
521
56533
Reaction
a phosphatidylcholine + H2O = 1,2-diacyl-sn-glycerol + phosphocholine
Other sequences found for EC No. 3.1.4.3

General information:

Sequence
  0 MGSEHPVDGM TRRQFFAKAA AATTAGAFMS LAGPIIEKAY GAGPCPGHLT DIEHIVLLMQ
 60 ENRSFDHYFG TLSDTRGFDD TTPPVVFAQS GWNPMTQAVD PAGVTLPYRF DTTRGPLVAG
120 ECVNDPDHSW IGMHNSWNGG ANDNWLPAQV PFSPLQGNVP VTMGFYTRRD LPIHYLLADT
180 FTVCDGYFCS LLGGTTPNRL YWMSAWIDPD GTDGGPVLIE PNIQPLQHYS WRIMPENLED
240 AGVSWKVYQN KLLGALNNTV VGYNGLVNDF KQAADPRSNL ARFGISPTYP LDFAADVRNN
300 RLPKVSWVLP GFLLSEHPAF PVNVGAVAIV DALRILLSNP AVWEKTALIV NYDENGGFFD
360 HVVPPTPPPG TPGEFVTVPD IDSVPGSGGI RGPIGLGFRV PCLVISPYSR GPLMVHDTFD
420 HTSTLKLIRA RFGVPVPNLT AWRDATVGDM TSTFNFAAPP NPSKPNLDHP RLNALPKLPQ
480 CVPNAVLGTV TKTAIPYRVP FPQSMPTQET APTRGIPSGL C
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
204940
Johansen K.A.,Gill R.E.,Vasil M.L.
Biochemical and molecular analysis of phospholipase C and phospholipase D activity in mycobacteria.
Infect. Immun.
64
3259-3266
1996
204941
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
204942
Raynaud C.,Guilhot C.,Rauzier J.,Bordat Y.,Pelicic V.,Manganelli R.,Smith I.,Gicquel B.,Jackson M.
Phospholipases C are involved in the virulence of Mycobacterium tuberculosis.
Mol. Microbiol.
45
203-217
2002
204943
Bakala N'goma J.C.,Schue M.,Carriere F.,Geerlof A.,Canaan S.
Evidence for the cytotoxic effects of Mycobacterium tuberculosis phospholipase C towards macrophages.
Biochim. Biophys. Acta
1801
1305-1313
2010
204944
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
0-0
2011