Sequence of A0A8J4KLN7_EUDCH
EC Number:3.4.17.24
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
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Reaction
This is a subfamily of enzymes that cleave C-terminal and/or side chain amino acids from tubulins. The dual-specificity enzymes can cleave both alpha- and gamma-linked L-glutamate from tubulins, removing the posttranslationally added polyglutamyl side chains from the C-terminal regions. In addition, the enzyme removes two glutamate residues from the C-terminus of beta-tubulin and detyrosinated alpha-tubulin (from which the C-terminal L-tyrosine has been removed by EC 3.4.17.17, tubulinyl-Tyr carboxypeptidase). The latter is cleaved to delta2-tubulin and further to delta3-tubulin.
Other sequences found for EC No. 3.4.17.24
General information:
Sequence
0 KFGVFPFQSS CDKDVTLNIL SVLTDLLSLG TGRRIQYVIS KGGSETLLQA LAAAARTDPP
60 DHSILLPLLR LLARVGQRDR KFGLKVQKAE ATDIILSLAR RNLGHHLHLT HCLWVLRVCA
120 SNVTTGTTLG INGAMELLFK VITPYSKRHV RTVRAAIEAL AALLKSKPNS RRAANRGYLG
180 GLLRLYQDWH HNDVSNNYIY IRRGLLLCLK HITNIQLGRE TFLGSRGMEI LFTSVQDCLS
240 CKNLDPIITT VIQILRKCYP KESLPVVTVR SSYLFPLPEN AKAESPCEGS EVDYESDGEE
300 EAEKDLDNED VESKEEDYDL ETDVNKLRSR PTLDRPEEEL GQYEAMCPEL SHNFQELESE
360 SEEDKSLEDR TENLCSTPFH FIPSATSVKY PNYRWRNQSV TEMGPDPEEK DFKVPLQSWT
420 KKKKCRWDLI DEKRNIVEAV QDADPCEEED PARSHMLTLR PLPKEAAWYK KMFYPECEAS
480 INPSPGGRLE SSDTVRNLLE KHQGDTSFQS PCFYVTRAKC VKSIPDYKDL GFPDFWGHQP
540 PPYSKPMLER KYGVQRDKVL DDVRRLIQPS DVIGRTVFDL DEPSHSSPGT PGCLTFFSKF
600 ESGNLRKAIQ VREFEYDLIT NADINSNQHH QWFYFEVRDM KSAVPYRFNI INCEKFNSQF
660 NYGMQPVMYS VKEALQGRPH WLRAGHDICY YKNHYHCSAA AGGGIRGKCY YTLTFSIKFP
720 HKDDVCYLAY HYPYTYSTMM SHLDMLEQNR NPRKVYWRQQ TLCQTLGGNP CPLLTITAMP
780 DSKKREDLEQ FYNRPYVFLM ARVHPGESNA SWVMKGTLEF LVSSDPIADL LRKCFIFKIV
840 PMLNPDGVIN GNHRCSLSGD DLNRQWLTPN SQLHPTIYHA KGLLYYLRSI GRAPLVFCDY
900 HGHSQKKNVF LYGCSIKETL WQAGCVVDTA VITEDVGYRT LPKILDKVAP AFVMNSCSFL
960 VEKSRESTAR VVVWKEMGVL RSYTMESTYC GCSHGLYKVS KSFK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
31842882
Pan H.,Cole T.L.,Bi X.,Fang M.,Zhou C.,Yang Z.,Ksepka D.T.,Hart T.,Bouzat J.L.,Argilla L.S.,Bertelsen M.F.,Boersma P.D.,Bost C.A.,Cherel Y.,Dann P.,Fiddaman S.R.,Howard P.,Labuschagne K.,Mattern T.,Miller G.,Parker P.,Phillips R.A.,Quillfeldt P.,Ryan P.G.,Taylor H.,Thompson D.R.,Young M.J.,Ellegaard M.R.,Gilbert M.T.P.,Sinding M.S.,Pacheco G.,Shepherd L.D.,Tennyson A.J.D.,Grosser S.,Kay E.,Nupen L.J.,Ellenberg U.,Houston D.M.,Reeve A.H.,Johnson K.,Masello J.F.,Stracke T.,McKinlay B.,Borboroglu P.G.,Zhang D.X.,Zhang G.
High-coverage genomes to elucidate the evolution of penguins.
Gigascience
8
0-0
2019
