Sequence of PKSA_DOTSE

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
noranthrone synthase
Q30DW5
Dothistroma septosporum
2399
259252
Reaction
7 malonyl-CoA + hexanoyl-[acyl-carrier protein] = 7 CoA + norsolorinic acid anthrone + [acyl-carrier protein] + 7 CO2 + 2 H2O
Sequences with same EC No.
Sequence
show sequence in fasta format
   0 MTHSNATRVL VFGDQTYDFV PKLRELFHVK DNPILTAFLE QSHYVVRAQM IQTLPPAEHK
  60 AARTFDLADM LKKYVAGKLN PAFQTALSCI TQLGVFMREF HDFTKPYPRH DSSYVLGICT
 120 GSLAAAAVSS SNSLSELLPI AVQTALIAFR LGLCVTDMRD RLESSEEDRT QPWSVVLFDT
 180 DEQTVTKAIK DFCTSNVLPK TKQPWITSAS SKTITISGAP RVLKKLSQEP ALKDKKTRQI
 240 PIYVPAHNSA LFTPEDVKSI LETTPVDTWS NYPTKLPFIS SVSGKMAWAD NYLAVIHLAL
 300 NQCLLESIGW GKVETELPRL LKSRGAENVL ITPITTSADR ALSAALSPTI SNIEVEKPTI
 360 NESFAHRPGS GKSKLAIVSM SGRFPEAQST DAFWDLLYKG LDVVKEVPKR RWDVETHVDP
 420 TGRARNKGAT KWGCWLDFAG EFDPRFFSIS PKEAPQMDPA QRMALMSTWE AMERGGIVPD
 480 TTPSTQRNRI GVFHGVTSND WMETNTAQNI DTYFITGGNR GFIPGRINFC FEFSGPSFTN
 540 DTACSSSLAA IHLACNSLWR GDCDTAVAGG TNMIFTPDGH AGLDKGFFLS RTGNCKPFDD
 600 KADGYCRAEG VGTVMVKRLE DALADGDPIL GTILDAKTNH SAMSDSMTRP FVPAQIDNME
 660 ACLSTAGVDP TSLDYIEMHG TGTQVGDAVE MESVLSVFAP NEQFRGKDQP LYVGSAKANI
 720 GHGEGVSGVT SLIKVLLMMQ NNTIPPHCGI KPGSKINHNY PDLAARNVHI AFEPKPFLRR
 780 EGKLRRVLIN NFSAAGGNTA LLIEDAPDRM PLSGQDPRTT QTVTISGHVG KSLSNNVANL
 840 LAHLKKNPTI DLSQLAYTVS ARRWHHLHRV AVAGTTVADI TAKLEKAIEN KEGVNRPKAK
 900 PSVFFAFTGQ GSQYLGMGKQ LYDSYPMFRS ELQGYDRLAQ SQGFPSFAHI FTETKGDVEQ
 960 NLPVVVQLAI TCLQMALFNL VTSFGIKASA VVGHSLGEYA ALYAAGVLSA SDTIYLVGKR
1020 AELLQDHCQR GTHAMLACKA SEWSLAEITA GKNVEVACVN GPEDTVLSGT VEEIGEVQKT
1080 LSAKSIKATL LKLPFAFHSA QVQPILEDFE ELAAGATFEK PKLAVISPLL GSVVEDEGVV
1140 GPNYLARHCR EAVGMVKALG VAKEKGIINE KTIVIEIGPK PLLCGMIKNI LGQNIVALPT
1200 LKDKGPDVWQ NLSNIFTTLY TGGLDINWTA FHAPFEPAKK VLQLPDYGWD LKDYFIQYEG
1260 DWVLHRHKIH CNCADAGKDV HNTSHYCPGK HTFAENVVVP GGAQKAVQEA PAAKTETKKM
1320 SKLDPTKEAY PGIPLTTTVH KVIEEKTEPL GAQFTVETDI SRKDVNSIAQ GHTVDSIPLC
1380 TPSFYADIAL QVGKYAMDRI RAGHPGAGAI DGRVDVTDLV VDKALIPHGK APQLLRTNVT
1440 MSWPPKMAAT TRSAKVTFKT YTADGKLDTD HAYCTVRFTT DSQQKSLQKK VPEYKAAIAK
1500 LRARDAKGEL THYNTKSGYK LMSSMAHFHP DYKLLDNLVL NEAENEAVSV MNFSSCTDAG
1560 IYAAHPAYVD AITQVGGFAM NAKDDTDIDK EVYVNHGWES FQVYKKMEKS VEYVVYSKMT
1620 KDPKGDMVHG DTIVLDGDEV VAFFRGLSLR SVPRKALRAV LQSAMDKGIR QRGGKPGAAK
1680 GAVAAPAPAK KMVEPVKAAS KKETPAAAAP PSPSKAAPPP APKPAALKAS VPKADPGKVD
1740 EALKIISEES GIALDELTDD SNFTDMGVDS LSSMVITSRL REDLELDLAP DFALFADCPT
1800 VASLRTFLAG AAGGPTDSPA AIATLEFGEP TPAKELEAGP ALKSTPISPG VQALQPVPAP
1860 TPAPKPVITS PAAPVSSKVF DDALQIISEE SGIALDELTD DSNFTDMGVD SLSSMVITSR
1920 LREDLELDLS PDWALFADCP TVASLRSFLG GSGPGSTAPA DADTPVDTTA AEIEAPVPNE
1980 AASYMPNSSQ ADVDDAVAAV IGNDPPRRPE PPKQAAAPAV ARTEALNAAL DIIAEESGVA
2040 AEDFTDDTIF SDIGIDSLCS MVISSRFREE LELDLDSQFS LFVDLPTVAQ LREFLTGSSA
2100 DSDSSSVASN PADPAATPPR SESSDTEPDD EAPSKPKSGP GSTDSCRSTN SVILQGKPKT
2160 AAKTLFLLPD GGGSASSYSV IPKLQSDVAV VGINCPYARD PENMTCTWQA MMQSFINEIK
2220 RRQPKGPYHL GGWSSGGAFA YVTAEKMIKQ GDEVGSLFIF DAPVPQVMEK LPREFYEAVN
2280 FTESTAVGTA EPPPYLIPHF MAVVDVMLDY KCKPLQTKKM PNVGLIWADS TVMKEDEAPK
2340 MKGMHFMIQK RTNFGPDGWD EVCPGAKFEI VKAVDTNHFT LMTKARVNYV SDLIDKVMG
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
196930
Bradshaw R.E.,Jin H.,Morgan B.S.,Schwelm A.,Teddy O.R.,Young C.A.,Zhang S.
A polyketide synthase gene required for biosynthesis of the aflatoxin-like toxin, dothistromin.
Mycopathologia
161
283-294
2006
196931
Zhang S.,Schwelm A.,Jin H.,Collins L.J.,Bradshaw R.E.
A fragmented aflatoxin-like gene cluster in the forest pathogen Dothistroma septosporum.
Fungal Genet. Biol.
44
1342-1354
2007
196933
Bradshaw R.E.,Bhatnagar D.,Ganley R.J.,Gillman C.J.,Monahan B.J.,Seconi J.M.
Dothistroma pini, a forest pathogen, contains homologs of aflatoxin biosynthetic pathway genes.
Appl. Environ. Microbiol.
68
2885-2892
2002
196934
Schwelm A.,Barron N.J.,Zhang S.,Bradshaw R.E.
Early expression of aflatoxin-like dothistromin genes in the forest pathogen Dothistroma septosporum.
Mycol. Res.
112
138-146
2008
196935
Schwelm A.,Bradshaw R.E.
Genetics of dothistromin biosynthesis of Dothistroma septosporum: an update.
Toxins
2
2680-2698
2010
196936
Chettri P.,Ehrlich K.C.,Cary J.W.,Collemare J.,Cox M.P.,Griffiths S.A.,Olson M.A.,de Wit P.J.,Bradshaw R.E.
Dothistromin genes at multiple separate loci are regulated by AflR.
Fungal Genet. Biol.
51
12-20
2013
196937
Bradshaw R.E.,Slot J.C.,Moore G.G.,Chettri P.,de Wit P.J.,Ehrlich K.C.,Ganley A.R.,Olson M.A.,Rokas A.,Carbone I.,Cox M.P.
Fragmentation of an aflatoxin-like gene cluster in a forest pathogen.
New Phytol.
198
525-535
2013
196938
Chettri P.,Ehrlich K.C.,Bradshaw R.E.
Regulation of the aflatoxin-like toxin dothistromin by AflJ.
Fungal Biol.
119
503-508
2015