Sequence of ACS2A_HUMAN

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
medium-chain acyl-CoA ligase
Q08AH3
Homo sapiens
577
64223
Reaction
ATP + a medium-chain fatty acid + CoA = AMP + diphosphate + a medium-chain acyl-CoA
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MHWLRKVQGL CTLWGTQMSS RTLYINSRQL VSLQWGHQEV PAKFNFASDV LDHWADMEKA
 60 GKRLPSPALW WVNGKGKELM WNFRELSENS QQAANVLSGA CGLQRGDRVA VVLPRVPEWW
120 LVILGCIRAG LIFMPGTIQM KSTDILYRLQ MSKAKAIVAG DEVIQEVDTV ASECPSLRIK
180 LLVSEKSCDG WLNFKKLLNE ASTTHHCVET GSQEASAIYF TSGTSGLPKM AEHSYSSLGL
240 KAKMDAGWTG LQASDIMWTI SDTGWILNIL CSLMEPWALG ACTFVHLLPK FDPLVILKTL
300 SSYPIKSMMG APIVYRMLLQ QDLSSYKFPH LQNCVTVGES LLPETLENWR AQTGLDIRES
360 YGQTETGLTC MVSKTMKIKP GYMGTAASCY DVQIIDDKGN VLPPGTEGDI GIRVKPIRPI
420 GIFSGYVDNP DKTAANIRGD FWLLGDRGIK DEDGYFQFMG RANDIINSSG YRIGPSEVEN
480 ALMEHPAVVE TAVISSPDPV RGEVVKAFVV LASQFLSHDP EQLTKELQQH VKSVTAPYKY
540 PRKIEFVLNL PKTVTGKIQR AKLRDKEWKM SGKARAQ
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
2185
Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet.
36
40-45
2004
2186
Martin J.,Han C.,Gordon L.A.,Terry A.,Prabhakar S.,She X.,Xie G.,Hellsten U.,Chan Y.M.,Altherr M.,Couronne O.,Aerts A.,Bajorek E.,Black S.,Blumer H.,Branscomb E.,Brown N.C.,Bruno W.J.,Buckingham J.M.,Callen D.F.,Campbell C.S.,Campbell M.L.,Campbell E.W.,Caoile C.,Challacombe J.F.,Chasteen L.A.,Chertkov O.,Chi H.C.,Christensen M.,Clark L.M.,Cohn J.D.,Denys M.,Detter J.C.,Dickson M.,Dimitrijevic-Bussod M.,Escobar J.,Fawcett J.J.,Flowers D.,Fotopulos D.,Glavina T.,Gomez M.,Gonzales E.,Goodstein D.,Goodwin L.A.,Grady D.L.,Grigoriev I.,Groza M.,Hammon N.,Hawkins T.,Haydu L.,Hildebrand C.E.,Huang W.,Israni S.,Jett J.,Jewett P.B.,Kadner K.,Kimball H.,Kobayashi A.,Krawczyk M.-C.,Leyba T.,Longmire J.L.,Lopez F.,Lou Y.,Lowry S.,Ludeman T.,Manohar C.F.,Mark G.A.,McMurray K.L.,Meincke L.J.,Morgan J.,Moyzis R.K.,Mundt M.O.,Munk A.C.,Nandkeshwar R.D.,Pitluck S.,Pollard M.,Predki P.,Parson-Quintana B.,Ramirez L.,Rash S.,Retterer J.,Ricke D.O.,Robinson D.L.,Rodriguez A.,Salamov A.,Saunders E.H.,Scott D.,Shough T.,Stallings R.L.,Stalvey M.,Sutherland R.D.,Tapia R.,Tesmer J.G.,Thayer N.,Thompson L.S.,Tice H.,Torney D.C.,Tran-Gyamfi M.,Tsai M.,Ulanovsky L.E.,Ustaszewska A.,Vo N.,White P.S.,Williams A.L.,Wills P.L.,Wu J.-R.,Wu K.,Yang J.,DeJong P.,Bruce D.,Doggett N.A.,Deaven L.,Schmutz J.,Grimwood J.,Richardson P.,Rokhsar D.S.,Eichler E.E.,Gilna P.,Lucas S.M.,Myers R.M.,Rubin E.M.,Pennacchio L.A.
The sequence and analysis of duplication-rich human chromosome 16.
Nature
432
988-994
2004
2187
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
2188
Loftus B.J.,Kim U.-J.,Sneddon V.P.,Kalush F.,Brandon R.,Fuhrmann J.,Mason T.,Crosby M.L.,Barnstead M.,Cronin L.,Mays A.D.,Cao Y.,Xu R.X.,Kang H.-L.,Mitchell S.,Eichler E.E.,Harris P.C.,Venter J.C.,Adams M.D.
Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.
Genomics
60
295-308
1999
2189
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
2190
van der Sluis R.,Erasmus E.
Xenobiotic/medium chain fatty acid: CoA ligase - a critical review on its role in fatty acid metabolism and the detoxification of benzoic acid and aspirin.
Expert Opin. Drug Metab. Toxicol.
12
1169-1179
2016
2192
Kochan G.,Pilka E.S.,von Delft F.,Oppermann U.,Yue W.W.
Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.
J. Mol. Biol.
388
997-1008
2009
2193
Iwai N.,Mannami T.,Tomoike H.,Ono K.,Iwanaga Y.
An acyl-CoA synthetase gene family in chromosome 16p12 may contribute to multiple risk factors.
Hypertension
41
1041-1046
2003
2194
Lindner I.,Rubin D.,Helwig U.,Nitz I.,Hampe J.,Schreiber S.,Schrezenmeir J.,Doering F.
The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.
Mol. Nutr. Food Res.
50
270-274
2006