Sequence of MMP14_PIG
EC Number:3.4.24.80
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
endopeptidase activity. Activates progelatinase A by cleavage of the propeptide at Asn37-/-Leu. Other bonds hydrolysed include Gly35-/-Ile in the propeptide of collagenase 3, and Asn341-/-Phe, Asp441-/-Leu and Gln354-/-Thr in the aggrecan interglobular domain
Other sequences found for EC No. 3.4.24.80
General information:
Sequence
0 MSPAPRPVRS LLLPLLTLAS ALASLSSAQS FSPEAWLQQY GYLPPGDLRT HTQRSPQSLS
60 AAIAAMQRFY GLRVTGKADA DTMKAMRRPR CGVPDKFGAE IKANVRRKRY AIQGLKWQHN
120 EITFCIQNYT PKVGEYATFE AIRKAFRVWE SATPLRFREV PYAYIREGHE KQADIMIFFA
180 EGFHGDSTPF DGEGGFLAHA YFPGPNIGGD THFDSAEPWT VRNEDLNGND IFLVAVHELG
240 HALGLEHSND PSAIMAPFYQ WMDTENFVLP DDDRRGIQQL YGSESGFPTK MPPQPRTTSK
300 PSVPDKPKNP TYGPNICDGN FDTVAMLRGE MFVFKERWFW RVRKNQVMDG YPMPIGQFWR
360 GLPASINTAY ERKDGKFVFF KGDKHWVFDE ASLEPGYPKH IKELGRRLPT DKIDAALFWM
420 PNGKDYFFRG NKYYRFNEEL RAVDSEYPKN IKVWEGIPES PRGSFMGSDE VFTYFYKGNK
480 YWKFNNQKLK VEPGYPKSAL RDWMGCPSGG RPDEGTEEET EVIIIEVDEE GSGAVSAAAV
540 VLPVLLLLLV LAVGLAVFFF RRHGTPKRLL YCQRSLLDKV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
189160
Caron C.,Xue J.,Bartlett J.D.
Expression and localization of membrane type 1 matrix metalloproteinase in tooth tissues.
Matrix Biol.
17
501-511
1998
