Sequence of KDTA_ECOLI
EC Number:2.4.99.12
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
lipid IVA 3-deoxy-D-manno-octulosonic acid transferase
P0AC75
Escherichia coli (strain K12)
425
47291
Reaction
lipid IVA + CMP-beta-Kdo = alpha-Kdo-(2->6)-lipid IVA + CMP
Other sequences found for EC No. 2.4.99.12
General information:
Sequence
0 MLELLYTALL YLIQPLIWIR LWVRGRKAPA YRKRWGERYG FYRHPLKPGG IMLHSVSVGE
60 TLAAIPLVRA LRHRYPDLPI TVTTMTPTGS ERVQSAFGKD VQHVYLPYDL PDALNRFLNK
120 VDPKLVLIME TELWPNLIAA LHKRKIPLVI ANARLSARSA AGYAKLGKFV RRLLRRITLI
180 AAQNEEDGAR FVALGAKNNQ VTVTGSLKFD ISVTPQLAAK AVTLRRQWAP HRPVWIATST
240 HEGEESVVIA AHQALLQQFP NLLLILVPRH PERFPDAINL VRQAGLSYIT RSSGEVPSTS
300 TQVVVGDTMG ELMLLYGIAD LAFVGGSLVE RGGHNPLEAA AHAIPVLMGP HTFNFKDICA
360 RLEQASGLIT VTDATTLAKE VSSLLTDADY RSFYGRHAVE VLYQNQGALQ RLLQLLEPYL
420 PPKTH
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
179708
Clementz T.,Raetz C.R.H.
A gene coding for 3-deoxy-D-manno-octulosonic-acid transferase in Escherichia coli. Identification, mapping, cloning, and sequencing.
J. Biol. Chem.
266
9687-9696
1991
179709
Sofia H.J.,Burland V.,Daniels D.L.,Plunkett G. III,Blattner F.R.
Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.
Nucleic Acids Res.
22
2576-2586
1994
179710
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
179711
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
179712
Clementz T.
The gene coding for 3-deoxy-manno-octulosonic acid transferase and the rfaQ gene are transcribed from divergently arranged promoters in Escherichia coli.
J. Bacteriol.
174
7750-7756
1992
179713
Belunis C.J.,Raetz C.R.
Biosynthesis of endotoxins. Purification and catalytic properties of 3-deoxy-D-manno-octulosonic acid transferase from Escherichia coli.
J. Biol. Chem.
267
9988-9997
1992
179714
Belunis C.J.,Clementz T.,Carty S.M.,Raetz C.R.
Inhibition of lipopolysaccharide biosynthesis and cell growth following inactivation of the kdtA gene in Escherichia coli.
J. Biol. Chem.
270
27646-27652
1995
179715
Brabetz W.,Lindner B.,Brade H.
Comparative analyses of secondary gene products of 3-deoxy-D-manno-oct-2-ulosonic acid transferases from Chlamydiaceae in Escherichia coli K-12.
Eur. J. Biochem.
267
5458-5465
2000
179716
Katz C.,Ron E.Z.
Dual role of FtsH in regulating lipopolysaccharide biosynthesis in Escherichia coli.
J. Bacteriol.
190
7117-7122
2008
179717
Chung H.S.,Raetz C.R.
Interchangeable domains in the Kdo transferases of Escherichia coli and Haemophilus influenzae.
Biochemistry
49
4126-4137
2010
