Sequence of CHSSA_CAEEL
EC Number:2.4.1.174
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase
Q7Z1Z1
Caenorhabditis elegans
736
83557
Reaction
UDP-N-acetyl-alpha-D-galactosamine + [protein]-3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine = UDP + [protein]-3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine
Other sequences found for EC No. 2.4.1.174
General information:
Sequence
0 MRVFQRSTCR MPVSRATVTI LLGILFGFSI TYYLTALKSL TNPIICGPEQ QIGGFDYLDV
60 ISQRADADVF TRSQSLPGHR RGLILVAIMT AAKYVDTRAY NVWKTWAQHI PGRVLIFVAE
120 GTESVHEDMP LIRLKGVDDT YPPQKKSFAM VKWLAENMAD EYDWFLRADD DLYIRGEELA
180 LFLRSVDSSK AHIIGQAGLG NSAEYGLLAL GSTDNYCMGG PGIVMSRDTL LKVSPHLESC
240 LQHMLTSHED VELGRCIRKH VGVACTWNYE MQKLFHNNQS AIKESYAKNM KELKDAITLH
300 PIKDPAVMRK VHLRNREIKL REARAKRSLL SSELSTAKAQ TLVRMTPNRT NDLTPWEYIN
360 NNKILFCADR VNCPRHTVDL SIRTEMADTI TQLFDEFNTN ARQRGRVLQF QSLQYGYMRV
420 EPTKGVDYVL DMLLWFKKFR PPNRTTISVR RHAYVQQTFG KLRSLSEGVF RSNMRANSTL
480 IEDPTLHMIM PLRGRAAIFA RFAQHLKSIC ARGGDDLAVS LTIVLYSSED EMENRETIEM
540 LRASFIPVTV IEMGDVSFSR GVALMRGAET LPANALLFFT DVDMLFTCDA LKRIKSNTIL
600 NAQIYFPIVF SEFSHESWSE NDKLLADAFH YGRGRGYFRH FGYGLAAMYK ADLMDVGGFD
660 TKIEGWGKED VDLFEKAIKN GRLRVIRVPE PGLVHIYHPI HCDENMPTAQ KDMCHGSKAA
720 SLASIDTLVE QIAQYT
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
17223
Mizuguchi S.,Uyama T.,Kitagawa H.,Nomura K.H.,Dejima K.,Gengyo-Ando K.,Mitani S.,Sugahara K.,Nomura K.
Chondroitin proteoglycans are involved in cell division of Caenorhabditis elegans.
Nature
423
443-448
2003
17224
Hwang H.Y.,Olson S.K.,Esko J.D.,Robert Horvitz H.
Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesis.
Nature
423
439-443
2003
17225
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
17226
Izumikawa T.,Kitagawa H.,Mizuguchi S.,Nomura K.H.,Nomura K.,Tamura J.,Gengyo-Ando K.,Mitani S.,Sugahara K.
Nematode chondroitin polymerizing factor showing cell-/organ-specific expression is indispensable for chondroitin synthesis and embryonic cell division.
J. Biol. Chem.
279
53755-53761
2004
17227
Suzuki N.,Toyoda H.,Sano M.,Nishiwaki K.
Chondroitin acts in the guidance of gonadal distal tip cells in C. elegans.
Dev. Biol.
300
635-646
2006
17228
Kitagawa H.,Izumikawa T.,Mizuguchi S.,Dejima K.,Nomura K.H.,Egusa N.,Taniguchi F.,Tamura J.,Gengyo-Ando K.,Mitani S.,Nomura K.,Sugahara K.
Expression of rib-1, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes, is indispensable for heparan sulfate synthesis and embryonic morphogenesis.
J. Biol. Chem.
282
8533-8544
2007
17229
Pedersen M.E.,Snieckute G.,Kagias K.,Nehammer C.,Multhaupt H.A.,Couchman J.R.,Pocock R.
An epidermal microRNA regulates neuronal migration through control of the cellular glycosylation state.
Science
341
1404-1408
2013
