Sequence of HYAL4_HUMAN
EC Number:3.2.1.35
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
hyaluronic acid hexasaccharide + H2O = hyaluronic acid disaccharide + hyaluronic acid tetrasaccharide
Other sequences found for EC No. 3.2.1.35
General information:
Sequence
0 MKVLSEGQLK LCVVQPVHLT SWLLIFFILK SISCLKPARL PIYQRKPFIA AWNAPTDQCL
60 IKYNLRLNLK MFPVIGSPLA KARGQNVTIF YVNRLGYYPW YTSQGVPING GLPQNISLQV
120 HLEKADQDIN YYIPAEDFSG LAVIDWEYWR PQWARNWNSK DVYRQKSRKL ISDMGKNVSA
180 TDIEYLAKVT FEESAKAFMK ETIKLGIKSR PKGLWGYYLY PDCHNYNVYA PNYSGSCPED
240 EVLRNNELSW LWNSSAALYP SIGVWKSLGD SENILRFSKF RVHESMRIST MTSHDYALPV
300 FVYTRLGYRD EPLFFLSKQD LVSTIGESAA LGAAGIVIWG DMNLTASKAN CTKVKQFVSS
360 DLGSYIANVT RAAEVCSLHL CRNNGRCIRK MWNAPSYLHL NPASYHIEAS EDGEFTVKGK
420 ASDTDLAVMA DTFSCHCYQG YEGADCREIK TADGCSGVSP SPGSLMTLCL LLLASYRSIQ
480 L
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
174517
Csoka A.B.,Scherer S.W.,Stern R.
Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31.
Genomics
60
356-361
1999
174518
Kaneiwa T.,Mizumoto S.,Sugahara K.,Yamada S.
Identification of human hyaluronidase-4 as a novel chondroitin sulfate hydrolase that preferentially cleaves the galactosaminidic linkage in the trisulfated tetrasaccharide sequence.
Glycobiology
20
300-309
2010
174519
Hillier L.W.,Fulton R.S.,Fulton L.A.,Graves T.A.,Pepin K.H.,Wagner-McPherson C.,Layman D.,Maas J.,Jaeger S.,Walker R.,Wylie K.,Sekhon M.,Becker M.C.,O'Laughlin M.D.,Schaller M.E.,Fewell G.A.,Delehaunty K.D.,Miner T.L.,Nash W.E.,Cordes M.,Du H.,Sun H.,Edwards J.,Bradshaw-Cordum H.,Ali J.,Andrews S.,Isak A.,Vanbrunt A.,Nguyen C.,Du F.,Lamar B.,Courtney L.,Kalicki J.,Ozersky P.,Bielicki L.,Scott K.,Holmes A.,Harkins R.,Harris A.,Strong C.M.,Hou S.,Tomlinson C.,Dauphin-Kohlberg S.,Kozlowicz-Reilly A.,Leonard S.,Rohlfing T.,Rock S.M.,Tin-Wollam A.-M.,Abbott A.,Minx P.,Maupin R.,Strowmatt C.,Latreille P.,Miller N.,Johnson D.,Murray J.,Woessner J.P.,Wendl M.C.,Yang S.-P.,Schultz B.R.,Wallis J.W.,Spieth J.,Bieri T.A.,Nelson J.O.,Berkowicz N.,Wohldmann P.E.,Cook L.L.,Hickenbotham M.T.,Eldred J.,Williams D.,Bedell J.A.,Mardis E.R.,Clifton S.W.,Chissoe S.L.,Marra M.A.,Raymond C.,Haugen E.,Gillett W.,Zhou Y.,James R.,Phelps K.,Iadanoto S.,Bubb K.,Simms E.,Levy R.,Clendenning J.,Kaul R.,Kent W.J.,Furey T.S.,Baertsch R.A.,Brent M.R.,Keibler E.,Flicek P.,Bork P.,Suyama M.,Bailey J.A.,Portnoy M.E.,Torrents D.,Chinwalla A.T.,Gish W.R.,Eddy S.R.,McPherson J.D.,Olson M.V.,Eichler E.E.,Green E.D.,Waterston R.H.,Wilson R.K.
The DNA sequence of human chromosome 7.
Nature
424
157-164
2003
174520
Scherer S.W.,Cheung J.,MacDonald J.R.,Osborne L.R.,Nakabayashi K.,Herbrick J.-A.,Carson A.R.,Parker-Katiraee L.,Skaug J.,Khaja R.,Zhang J.,Hudek A.K.,Li M.,Haddad M.,Duggan G.E.,Fernandez B.A.,Kanematsu E.,Gentles S.,Christopoulos C.C.,Choufani S.,Kwasnicka D.,Zheng X.H.,Lai Z.,Nusskern D.R.,Zhang Q.,Gu Z.,Lu F.,Zeesman S.,Nowaczyk M.J.,Teshima I.,Chitayat D.,Shuman C.,Weksberg R.,Zackai E.H.,Grebe T.A.,Cox S.R.,Kirkpatrick S.J.,Rahman N.,Friedman J.M.,Heng H.H.Q.,Pelicci P.G.,Lo-Coco F.,Belloni E.,Shaffer L.G.,Pober B.,Morton C.C.,Gusella J.F.,Bruns G.A.P.,Korf B.R.,Quade B.J.,Ligon A.H.,Ferguson H.,Higgins A.W.,Leach N.T.,Herrick S.R.,Lemyre E.,Farra C.G.,Kim H.-G.,Summers A.M.,Gripp K.W.,Roberts W.,Szatmari P.,Winsor E.J.T.,Grzeschik K.-H.,Teebi A.,Minassian B.A.,Kere J.,Armengol L.,Pujana M.A.,Estivill X.,Wilson M.D.,Koop B.F.,Tosi S.,Moore G.E.,Boright A.P.,Zlotorynski E.,Kerem B.,Kroisel P.M.,Petek E.,Oscier D.G.,Mould S.J.,Doehner H.,Doehner K.,Rommens J.M.,Vincent J.B.,Venter J.C.,Li P.W.,Mural R.J.,Adams M.D.,Tsui L.-C.
Human chromosome 7: DNA sequence and biology.
Science
300
767-772
2003
174522
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
174523
Jedrzejas M.J.,Stern R.
Structures of vertebrate hyaluronidases and their unique enzymatic mechanism of hydrolysis.
Proteins
61
227-238
2005
174524
Jia W.,Lu Z.,Fu Y.,Wang H.P.,Wang L.H.,Chi H.,Yuan Z.F.,Zheng Z.B.,Song L.N.,Han H.H.,Liang Y.M.,Wang J.L.,Cai Y.,Zhang Y.K.,Deng Y.L.,Ying W.T.,He S.M.,Qian X.H.
A strategy for precise and large scale identification of core fucosylated glycoproteins.
Mol. Cell. Proteomics
8
913-923
2009
