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Sequence of H17B6_HUMAN

EC Number:1.1.1.53

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
3alpha(or 20beta)-hydroxysteroid dehydrogenase
O14756
Homo sapiens
317
35966
Reaction
androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+
Other sequences found for EC No. 1.1.1.53

General information:

Sequence
show sequence in fasta format
  0 MWLYLAAFVG LYYLLHWYRE RQVVSHLQDK YVFITGCDSG FGNLLARQLD ARGLRVLAAC
 60 LTEKGAEQLR GQTSDRLETV TLDVTKMESI AAATQWVKEH VGDRGLWGLV NNAGILTPIT
120 LCEWLNTEDS MNMLKVNLIG VIQVTLSMLP LVRRARGRIV NVSSILGRVA FFVGGYCVSK
180 YGVEAFSDIL RREIQHFGVK ISIVEPGYFR TGMTNMTQSL ERMKQSWKEA PKHIKETYGQ
240 QYFDALYNIM KEGLLNCSTN LNLVTDCMEH ALTSVHPRTR YSAGWDAKFF FIPLSYLPTS
300 LADYILTRSW PKPAQAV
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
169880
Biswas M.G.,Russell D.W.
Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate.
J. Biol. Chem.
272
15959-15966
1997
169881
Huang X.-F.,Luu-The V.
Molecular characterization of a first human 3(alpha-->beta)-hydroxysteroid epimerase.
J. Biol. Chem.
275
29452-29457
2000
169882
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
169883
Chetyrkin S.V.,Hu J.,Gough W.H.,Dumaual N.,Kedishvili N.Y.
Further characterization of human microsomal 3alpha-hydroxysteroid dehydrogenase.
Arch. Biochem. Biophys.
386
1-10
2001
169884
Huang X.-F.,Luu-The V.
Gene structure, chromosomal localization and analysis of 3-ketosteroid reductase activity of the human 3(alpha-->beta)-hydroxysteroid epimerase.
Biochim. Biophys. Acta
1520
124-130
2001
169885
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014