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Sequence of SLS_LEIMA

EC Number:2.7.1.227

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
inositol phosphorylceramide synthase
E9AFX2
Leishmania major
338
37644
Reaction
1-phosphatidyl-1D-myo-inositol + a very-long-chain (2'R)-2'-hydroxyphytoceramide = 1,2-diacyl-sn-glycerol + a very-long-chain inositol phospho-(2'R)-2'-hydroxyphytoceramide
Other sequences found for EC No. 2.7.1.227

General information:

Sequence
show sequence in fasta format
  0 MTSHVTAHDV GGNEDIGTDH VPWYKQPLPL CTQVMRFILL LLLTVMFLGV AILVANARMP
 60 DPEKVRPLPD LLLESIPKVA LLENGTNVII FLLNATTVVV GFKVFLLERH MNGLPRVTFL
120 VGVPKIGSFL NRMAFGVLDS GRRPFPLKNV FPIMAIRFLT SYAVVMVFRA FVIMGTSYPA
180 TDNHCQNPQV IEHPVLNVIL TLVTLGSGAI HCGDLMFSGH TMILSLAFIL AWDYSPFLHP
240 WAVRVWVSVL LPISYYCILA SRSHYTDDIL VAMYVMIATY KVIDHAETGA PWQMQLLIRW
300 MPWPGANTIE KWTADEVVVV VQTPAEDSTD ASAALPEH
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
232257
Ivens A.C.,Peacock C.S.,Worthey E.A.,Murphy L.,Aggarwal G.,Berriman M.,Sisk E.,Rajandream M.A.,Adlem E.,Aert R.,Anupama A.,Apostolou Z.,Attipoe P.,Bason N.,Bauser C.,Beck A.,Beverley S.M.,Bianchettin G.,Borzym K.,Bothe G.,Bruschi C.V.,Collins M.,Cadag E.,Ciarloni L.,Clayton C.,Coulson R.M.R.,Cronin A.,Cruz A.K.,Davies R.M.,De Gaudenzi J.,Dobson D.E.,Duesterhoeft A.,Fazelina G.,Fosker N.,Frasch A.C.,Fraser A.,Fuchs M.,Gabel C.,Goble A.,Goffeau A.,Harris D.,Hertz-Fowler C.,Hilbert H.,Horn D.,Huang Y.,Klages S.,Knights A.,Kube M.,Larke N.,Litvin L.,Lord A.,Louie T.,Marra M.,Masuy D.,Matthews K.,Michaeli S.,Mottram J.C.,Mueller-Auer S.,Munden H.,Nelson S.,Norbertczak H.,Oliver K.,O'neil S.,Pentony M.,Pohl T.M.,Price C.,Purnelle B.,Quail M.A.,Rabbinowitsch E.,Reinhardt R.,Rieger M.,Rinta J.,Robben J.,Robertson L.,Ruiz J.C.,Rutter S.,Saunders D.,Schaefer M.,Schein J.,Schwartz D.C.,Seeger K.,Seyler A.,Sharp S.,Shin H.,Sivam D.,Squares R.,Squares S.,Tosato V.,Vogt C.,Volckaert G.,Wambutt R.,Warren T.,Wedler H.,Woodward J.,Zhou S.,Zimmermann W.,Smith D.F.,Blackwell J.M.,Stuart K.D.,Barrell B.G.,Myler P.J.
The genome of the kinetoplastid parasite, Leishmania major.
Science
309
436-442
2005
232258
Sevova E.S.,Goren M.A.,Schwartz K.J.,Hsu F.F.,Turk J.,Fox B.G.,Bangs J.D.
Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosomatid protozoa.
J. Biol. Chem.
285
20580-20587
2010
232259
Sutterwala S.S.,Hsu F.F.,Sevova E.S.,Schwartz K.J.,Zhang K.,Key P.,Turk J.,Beverley S.M.,Bangs J.D.
Developmentally regulated sphingolipid synthesis in African trypanosomes.
Mol. Microbiol.
70
281-296
2008