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Sequence of CFR_MAMSC

EC Number:2.1.1.224

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
23S rRNA (adenine2503-C8)-methyltransferase
Q9FBG4
Mammaliicoccus sciuri
349
39862
Reaction
2 S-adenosyl-L-methionine + adenine2503 in 23S rRNA + 2 reduced [2Fe-2S] ferredoxin = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 8-methyladenine2503 in 23S rRNA + 2 oxidized [2Fe-2S] ferredoxin
Other sequences found for EC No. 2.1.1.224

General information:

Sequence
show sequence in fasta format
  0 MNFNNKTKYG KIQEFLRSNN EPDYRIKQIT NAIFKQRISR FEDMKVLPKL LREDLINNFG
 60 ETVLNIKLLA EQNSEQVTKV LFEVSKNERV ETVNMKYKAG WESFCISSQC GCNFGCKFCA
120 TGDIGLKKNL TVDEITDQVL YFHLLGHQID SISFMGMGEA LANRQVFDAL DSFTDPNLFA
180 LSPRRLSIST IGIIPSIKKI TQEYPQVNLT FSLHSPYSEE RSKLMPINDR YPIDEVMNIL
240 DEHIRLTSRK VYIAYIMLPG VNDSLEHANE VVSLLKSRYK SGKLYHVNLI RYNPTISAPE
300 MYGEANEGQV EAFYKVLKSA GIHVTIRSQF GIDIDAACGQ LYGNYQNSQ
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
16319
Schwarz S.,Werckenthin C.,Kehrenberg C.
Identification of a plasmid-borne chloramphenicol-florfenicol resistance gene in Staphylococcus sciuri.
Antimicrob. Agents Chemother.
44
2530-2533
2000
16320
Kehrenberg C.,Ojo K.K.,Schwarz S.
Nucleotide sequence and organization of the multiresistance plasmid pSCFS1 from Staphylococcus sciuri.
J. Antimicrob. Chemother.
54
936-939
2004
16321
Giessing A.M.B.,Jensen S.S.,Rasmussen A.,Hansen L.H.,Gondela A.,Long K.,Vester B.,Kirpekar F.
Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria.
RNA
15
327-336
2009