Sequence of ENOA_HUMAN
EC Number:4.2.1.11
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
2-phospho-D-glycerate = phosphoenolpyruvate + H2O
Other sequences found for EC No. 4.2.1.11
General information:
Sequence
0 MSILKIHARE IFDSRGNPTV EVDLFTSKGL FRAAVPSGAS TGIYEALELR DNDKTRYMGK
60 GVSKAVEHIN KTIAPALVSK KLNVTEQEKI DKLMIEMDGT ENKSKFGANA ILGVSLAVCK
120 AGAVEKGVPL YRHIADLAGN SEVILPVPAF NVINGGSHAG NKLAMQEFMI LPVGAANFRE
180 AMRIGAEVYH NLKNVIKEKY GKDATNVGDE GGFAPNILEN KEGLELLKTA IGKAGYTDKV
240 VIGMDVAASE FFRSGKYDLD FKSPDDPSRY ISPDQLADLY KSFIKDYPVV SIEDPFDQDD
300 WGAWQKFTAS AGIQVVGDDL TVTNPKRIAK AVNEKSCNCL LLKVNQIGSV TESLQACKLA
360 QANGWGVMVS HRSGETEDTF IADLVVGLCT GQIKTGAPCR SERLAKYNQL LRIEEELGSK
420 AKFAGRNFRN PLAK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
158008
Giallongo A.,Feo S.,Moore R.,Croce C.M.,Showe L.C.
Molecular cloning and nucleotide sequence of a full-length cDNA for human alpha enolase.
Proc. Natl. Acad. Sci. U.S.A.
83
6741-6745
1986
158009
Giallongo A.,Oliva D.,Cali L.,Barba G.,Barbieri G.,Feo S.
Structure of the human gene for alpha-enolase.
Eur. J. Biochem.
190
567-573
1990
158010
Ray R.,Miller D.M.
Cloning and characterization of a human c-myc promoter-binding protein.
Mol. Cell. Biol.
11
2154-2161
1991
158011
Walter M.,Berg H.,Leidenberger F.A.,Schweppe K.W.,Northemann W.
Autoreactive epitopes within the human alpha-enolase and their recognition by sera from patients with endometriosis.
J. Autoimmun.
8
931-945
1995
158013
Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet.
36
40-45
2004
158015
Bechtel S.,Rosenfelder H.,Duda A.,Schmidt C.P.,Ernst U.,Wellenreuther R.,Mehrle A.,Schuster C.,Bahr A.,Bloecker H.,Heubner D.,Hoerlein A.,Michel G.,Wedler H.,Koehrer K.,Ottenwaelder B.,Poustka A.,Wiemann S.,Schupp I.
The full-ORF clone resource of the German cDNA consortium.
BMC Genomics
8
399-399
2007
158017
Gregory S.G.,Barlow K.F.,McLay K.E.,Kaul R.,Swarbreck D.,Dunham A.,Scott C.E.,Howe K.L.,Woodfine K.,Spencer C.C.A.,Jones M.C.,Gillson C.,Searle S.,Zhou Y.,Kokocinski F.,McDonald L.,Evans R.,Phillips K.,Atkinson A.,Cooper R.,Jones C.,Hall R.E.,Andrews T.D.,Lloyd C.,Ainscough R.,Almeida J.P.,Ambrose K.D.,Anderson F.,Andrew R.W.,Ashwell R.I.S.,Aubin K.,Babbage A.K.,Bagguley C.L.,Bailey J.,Beasley H.,Bethel G.,Bird C.P.,Bray-Allen S.,Brown J.Y.,Brown A.J.,Buckley D.,Burton J.,Bye J.,Carder C.,Chapman J.C.,Clark S.Y.,Clarke G.,Clee C.,Cobley V.,Collier R.E.,Corby N.,Coville G.J.,Davies J.,Deadman R.,Dunn M.,Earthrowl M.,Ellington A.G.,Errington H.,Frankish A.,Frankland J.,French L.,Garner P.,Garnett J.,Gay L.,Ghori M.R.J.,Gibson R.,Gilby L.M.,Gillett W.,Glithero R.J.,Grafham D.V.,Griffiths C.,Griffiths-Jones S.,Grocock R.,Hammond S.,Harrison E.S.I.,Hart E.,Haugen E.,Heath P.D.,Holmes S.,Holt K.,Howden P.J.,Hunt A.R.,Hunt S.E.,Hunter G.,Isherwood J.,James R.,Johnson C.,Johnson D.,Joy A.,Kay M.,Kershaw J.K.,Kibukawa M.,Kimberley A.M.,King A.,Knights A.J.,Lad H.,Laird G.,Lawlor S.,Leongamornlert D.A.,Lloyd D.M.,Loveland J.,Lovell J.,Lush M.J.,Lyne R.,Martin S.,Mashreghi-Mohammadi M.,Matthews L.,Matthews N.S.W.,McLaren S.,Milne S.,Mistry S.,Moore M.J.F.,Nickerson T.,O'Dell C.N.,Oliver K.,Palmeiri A.,Palmer S.A.,Parker A.,Patel D.,Pearce A.V.,Peck A.I.,Pelan S.,Phelps K.,Phillimore B.J.,Plumb R.,Rajan J.,Raymond C.,Rouse G.,Saenphimmachak C.,Sehra H.K.,Sheridan E.,Shownkeen R.,Sims S.,Skuce C.D.,Smith M.,Steward C.,Subramanian S.,Sycamore N.,Tracey A.,Tromans A.,Van Helmond Z.,Wall M.,Wallis J.M.,White S.,Whitehead S.L.,Wilkinson J.E.,Willey D.L.,Williams H.,Wilming L.,Wray P.W.,Wu Z.,Coulson A.,Vaudin M.,Sulston J.E.,Durbin R.M.,Hubbard T.,Wooster R.,Dunham I.,Carter N.P.,McVean G.,Ross M.T.,Harrow J.,Olson M.V.,Beck S.,Rogers J.,Bentley D.R.
The DNA sequence and biological annotation of human chromosome 1.
Nature
441
315-321
2006
158019
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
158020
Ji H.,Reid G.E.,Moritz R.L.,Eddes J.S.,Burgess A.W.,Simpson R.J.
A two-dimensional gel database of human colon carcinoma proteins.
Electrophoresis
18
605-613
1997
158023
Onyango P.,Lubyova B.,Gardellin P.,Kurzbauer R.,Weith A.
Molecular cloning and expression analysis of five novel genes in chromosome 1p36.
Genomics
50
187-198
1998
158024
Yu W.,Andersson B.,Worley K.C.,Muzny D.M.,Ding Y.,Liu W.,Ricafrente J.Y.,Wentland M.A.,Lennon G.,Gibbs R.A.
Large-scale concatenation cDNA sequencing.
Genome Res.
7
353-358
1997
158025
Sugahara T.,Nakajima H.,Shirahata S.,Murakami H.
Purification and characterization of immunoglobulin production stimulating factor-II beta derived from Namalwa cells.
Cytotechnology
10
137-146
1992
158026
Mohamad R.M.,Hamdan M.Y.,Maki A.,Al-Katib A.
Induced expression of alpha-enolase in differentiated diffuse large cell lymphoma.
Enzyme Protein
48
37-44
1994
158027
Ghosh A.K.,Steele R.,Ray R.B.
Functional domains of c-myc promoter binding protein 1 involved in transcriptional repression and cell growth regulation.
Mol. Cell. Biol.
19
2880-2886
1999
158028
Feo S.,Arcuri D.,Piddini E.,Passantino R.,Giallongo A.
ENO1 gene product binds to the c-myc promoter and acts as a transcriptional repressor: relationship with Myc promoter-binding protein 1 (MBP-1).
FEBS Lett.
473
47-52
2000
158029
Lopez-Alemany R.,Longstaff C.,Hawley S.,Mirshahi M.,Fabregas P.,Jardi M.,Merton E.,Miles L.A.,Felez J.
Inhibition of cell surface mediated plasminogen activation by a monoclonal antibody against alpha-enolase.
Am. J. Hematol.
72
234-242
2003
158030
Arza B.,Felez J.,Lopez-Alemany R.,Miles L.A.,Munoz-Canoves P.
Identification of an epitope of alpha-enolase (a candidate plasminogen receptor) by phage display.
Thromb. Haemost.
78
1097-1103
1997
158031
Adamus G.,Amundson D.,Seigel G.M.,Machnicki M.
Anti-enolase-alpha autoantibodies in cancer-associated retinopathy: epitope mapping and cytotoxicity on retinal cells.
J. Autoimmun.
11
671-677
1998
158032
Subramanian A.,Miller D.M.
Structural analysis of alpha-enolase. Mapping the functional domains involved in down-regulation of the c-myc protooncogene.
J. Biol. Chem.
275
5958-5965
2000
158033
Pancholi V.
Multifunctional alpha-enolase: its role in diseases.
Cell. Mol. Life Sci.
58
902-920
2001
158034
Ghosh A.K.,Majumder M.,Steele R.,White R.A.,Ray R.B.
A novel 16-kilodalton cellular protein physically interacts with and antagonizes the functional activity of c-myc promoter-binding protein 1.
Mol. Cell. Biol.
21
655-662
2001
158035
Ochi H.,Horiuchi I.,Araki N.,Toda T.,Araki T.,Sato K.,Murai H.,Osoegawa M.,Yamada T.,Okamura K.,Ogino T.,Mizumoto K.,Yamashita H.,Saya H.,Kira J.
Proteomic analysis of human brain identifies alpha-enolase as a novel autoantigen in Hashimoto's encephalopathy.
FEBS Lett.
528
197-202
2002
158036
Giannakopoulos N.V.,Luo J.K.,Papov V.,Zou W.,Lenschow D.J.,Jacobs B.S.,Borden E.C.,Li J.,Virgin H.W.,Zhang D.E.
Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.
Biochem. Biophys. Res. Commun.
336
496-506
2005
158037
Rush J.,Moritz A.,Lee K.A.,Guo A.,Goss V.L.,Spek E.J.,Zhang H.,Zha X.-M.,Polakiewicz R.D.,Comb M.J.
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
Nat. Biotechnol.
23
94-101
2005
158038
Leong W.F.,Chow V.T.
Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.
Cell. Microbiol.
8
565-580
2006
158039
Wong J.J.,Pung Y.F.,Sze N.S.,Chin K.C.
HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets.
Proc. Natl. Acad. Sci. U.S.A.
103
10735-10740
2006
158040
Dephoure N.,Zhou C.,Villen J.,Beausoleil S.A.,Bakalarski C.E.,Elledge S.J.,Gygi S.P.
A quantitative atlas of mitotic phosphorylation.
Proc. Natl. Acad. Sci. U.S.A.
105
10762-10767
2008
158041
Mayya V.,Lundgren D.H.,Hwang S.-I.,Rezaul K.,Wu L.,Eng J.K.,Rodionov V.,Han D.K.
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Sci. Signal.
2
0-0
2009
158042
Choudhary C.,Kumar C.,Gnad F.,Nielsen M.L.,Rehman M.,Walther T.C.,Olsen J.V.,Mann M.
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Science
325
834-840
2009
158043
Olsen J.V.,Vermeulen M.,Santamaria A.,Kumar C.,Miller M.L.,Jensen L.J.,Gnad F.,Cox J.,Jensen T.S.,Nigg E.A.,Brunak S.,Mann M.
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
Sci. Signal.
3
0-0
2010
158044
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
158045
Peng C.,Lu Z.,Xie Z.,Cheng Z.,Chen Y.,Tan M.,Luo H.,Zhang Y.,He W.,Yang K.,Zwaans B.M.,Tishkoff D.,Ho L.,Lombard D.,He T.C.,Dai J.,Verdin E.,Ye Y.,Zhao Y.
The first identification of lysine malonylation substrates and its regulatory enzyme.
Mol. Cell. Proteomics
10
0-0
2011
158046
Rosenow A.,Noben J.P.,Jocken J.,Kallendrusch S.,Fischer-Posovszky P.,Mariman E.C.,Renes J.
Resveratrol-induced changes of the human adipocyte secretion profile.
J. Proteome Res.
11
4733-4743
2012
158047
Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
J. Proteome Res.
12
260-271
2013
158048
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
158049
Vaca Jacome A.S.,Rabilloud T.,Schaeffer-Reiss C.,Rompais M.,Ayoub D.,Lane L.,Bairoch A.,Van Dorsselaer A.,Carapito C.
N-terminome analysis of the human mitochondrial proteome.
Proteomics
15
2519-2524
2015
158050
Hendriks I.A.,Lyon D.,Young C.,Jensen L.J.,Vertegaal A.C.,Nielsen M.L.
Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
Nat. Struct. Mol. Biol.
24
325-336
2017
158051
Burr M.L.,Sparbier C.E.,Chan Y.C.,Williamson J.C.,Woods K.,Beavis P.A.,Lam E.Y.N.,Henderson M.A.,Bell C.C.,Stolzenburg S.,Gilan O.,Bloor S.,Noori T.,Morgens D.W.,Bassik M.C.,Neeson P.J.,Behren A.,Darcy P.K.,Dawson S.J.,Voskoboinik I.,Trapani J.A.,Cebon J.,Lehner P.J.,Dawson M.A.
CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity.
Nature
549
101-105
2017
158052
Huang H.,Tang S.,Ji M.,Tang Z.,Shimada M.,Liu X.,Qi S.,Locasale J.W.,Roeder R.G.,Zhao Y.,Li X.
p300-mediated lysine 2-hydroxyisobutyrylation regulates glycolysis.
Mol. Cell
70
663-678
2018
158053
Kang H.J.,Jung S.K.,Kim S.J.,Chung S.J.
Structure of human alpha-enolase (hENO1), a multifunctional glycolytic enzyme.
Acta Crystallogr. D
64
651-657
2008
