Sequence of PDC5_YEAST

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
pyruvate decarboxylase
P16467
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
563
61912
Reaction
a 2-oxo carboxylate = an aldehyde + CO2
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MSEITLGKYL FERLSQVNCN TVFGLPGDFN LSLLDKLYEV KGMRWAGNAN ELNAAYAADG
 60 YARIKGMSCI ITTFGVGELS ALNGIAGSYA EHVGVLHVVG VPSISSQAKQ LLLHHTLGNG
120 DFTVFHRMSA NISETTAMIT DIANAPAEID RCIRTTYTTQ RPVYLGLPAN LVDLNVPAKL
180 LETPIDLSLK PNDAEAEAEV VRTVVELIKD AKNPVILADA CASRHDVKAE TKKLMDLTQF
240 PVYVTPMGKG AIDEQHPRYG GVYVGTLSRP EVKKAVESAD LILSIGALLS DFNTGSFSYS
300 YKTKNIVEFH SDHIKIRNAT FPGVQMKFAL QKLLDAIPEV VKDYKPVAVP ARVPITKSTP
360 ANTPMKQEWM WNHLGNFLRE GDIVIAETGT SAFGINQTTF PTDVYAIVQV LWGSIGFTVG
420 ALLGATMAAE ELDPKKRVIL FIGDGSLQLT VQEISTMIRW GLKPYIFVLN NNGYTIEKLI
480 HGPHAEYNEI QGWDHLALLP TFGARNYETH RVATTGEWEK LTQDKDFQDN SKIRMIEVML
540 PVFDAPQNLV KQAQLTAATN AKQ
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1073766
Hohmann S.,Cederberg H.
Autoregulation may control the expression of yeast pyruvate decarboxylase structural genes PDC1 and PDC5.
Eur. J. Biochem.
188
615-621
1990
1073767
Johnston M.,Hillier L.W.,Riles L.,Albermann K.,Andre B.,Ansorge W.,Benes V.,Brueckner M.,Delius H.,Dubois E.,Duesterhoeft A.,Entian K.-D.,Floeth M.,Goffeau A.,Hebling U.,Heumann K.,Heuss-Neitzel D.,Hilbert H.,Hilger F.,Kleine K.,Koetter P.,Louis E.J.,Messenguy F.,Mewes H.-W.,Miosga T.,Moestl D.,Mueller-Auer S.,Nentwich U.,Obermaier B.,Piravandi E.,Pohl T.M.,Portetelle D.,Purnelle B.,Rechmann S.,Rieger M.,Rinke M.,Rose M.,Scharfe M.,Scherens B.,Scholler P.,Schwager C.,Schwarz S.,Underwood A.P.,Urrestarazu L.A.,Vandenbol M.,Verhasselt P.,Vierendeels F.,Voet M.,Volckaert G.,Voss H.,Wambutt R.,Wedler E.,Wedler H.,Zimmermann F.K.,Zollner A.,Hani J.,Hoheisel J.D.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
Nature
387
87-90
1997
1073768
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
1073769
Chen G.C.,Jordan F.
Brewers' yeast pyruvate decarboxylase produces acetoin from acetaldehyde: a novel tool to study the mechanism of steps subsequent to carbon dioxide loss.
Biochemistry
23
3576-3582
1984
1073770
Dickinson J.R.,Lanterman M.M.,Danner D.J.,Pearson B.M.,Sanz P.,Harrison S.J.,Hewlins M.J.
A 13C nuclear magnetic resonance investigation of the metabolism of leucine to isoamyl alcohol in Saccharomyces cerevisiae.
J. Biol. Chem.
272
26871-26878
1997
1073771
Iding H.,Siegert P.,Mesch K.,Pohl M.
Application of alpha-keto acid decarboxylases in biotransformations.
Biochim. Biophys. Acta
1385
307-322
1998
1073772
Hohmann S.,Meacock P.A.
Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation.
Biochim. Biophys. Acta
1385
201-219
1998
1073773
Dickinson J.R.,Harrison S.J.,Hewlins M.J.
An investigation of the metabolism of valine to isobutyl alcohol in Saccharomyces cerevisiae.
J. Biol. Chem.
273
25751-25756
1998
1073774
Eberhardt I.,Cederberg H.,Li H.,Konig S.,Jordan F.,Hohmann S.
Autoregulation of yeast pyruvate decarboxylase gene expression requires the enzyme but not its catalytic activity.
Eur. J. Biochem.
262
191-201
1999
1073775
Muller E.H.,Richards E.J.,Norbeck J.,Byrne K.L.,Karlsson K.A.,Pretorius G.H.,Meacock P.A.,Blomberg A.,Hohmann S.
Thiamine repression and pyruvate decarboxylase autoregulation independently control the expression of the Saccharomyces cerevisiae PDC5 gene.
FEBS Lett.
449
245-250
1999
1073776
Flikweert M.T.,de Swaaf M.,van Dijken J.P.,Pronk J.T.
Growth requirements of pyruvate-decarboxylase-negative Saccharomyces cerevisiae.
FEMS Microbiol. Lett.
174
73-79
1999
1073777
Neuser F.,Zorn H.,Berger R.G.
Generation of odorous acyloins by yeast pyruvate decarboxylases and their occurrence in sherry and soy sauce.
J. Agric. Food Chem.
48
6191-6195
2000
1073778
Dickinson J.R.,Harrison S.J.,Dickinson J.A.,Hewlins M.J.
An investigation of the metabolism of isoleucine to active Amyl alcohol in Saccharomyces cerevisiae.
J. Biol. Chem.
275
10937-10942
2000
1073779
Vuralhan Z.,Morais M.A.,Tai S.L.,Piper M.D.,Pronk J.T.
Identification and characterization of phenylpyruvate decarboxylase genes in Saccharomyces cerevisiae.
Appl. Environ. Microbiol.
69
4534-4541
2003
1073780
Dickinson J.R.,Salgado L.E.,Hewlins M.J.
The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae.
J. Biol. Chem.
278
8028-8034
2003
1073781
Huh W.-K.,Falvo J.V.,Gerke L.C.,Carroll A.S.,Howson R.W.,Weissman J.S.,O'Shea E.K.
Global analysis of protein localization in budding yeast.
Nature
425
686-691
2003
1073782
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
1073783
Romagnoli G.,Luttik M.A.,Koetter P.,Pronk J.T.,Daran J.M.
Substrate specificity of thiamine pyrophosphate-dependent 2-oxo-acid decarboxylases in Saccharomyces cerevisiae.
Appl. Environ. Microbiol.
78
7538-7548
2012
1073784
Branduardi P.,Longo V.,Berterame N.M.,Rossi G.,Porro D.
A novel pathway to produce butanol and isobutanol in Saccharomyces cerevisiae.
Biotechnol. Biofuels
6
68-68
2013