Sequence of ALT_BPT4

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
NAD+ ADP-ribosyltransferase
P12726
Enterobacteria phage T4
682
75818
Reaction
NAD+ + (ADP-D-ribosyl)n-acceptor = nicotinamide + (ADP-D-ribosyl)n+1-acceptor + H+
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MELITELFDE DTTLPITNLY PKKKIPQIFS VHVDDAIEQP GFRLCTYTSG GDTNRDLKMG
 60 DKMMHIVPFT LTAKGSIAKL KGLGPSPINY INSVFTVAMQ TMRQYKIDAC MLRILKSKTA
120 GQARQIQVIA DRLIRSRSGG RYVLLKELWD YDKKYAYILI HRKNVSLEDI PGVPEISTEL
180 FTKVESKVGD VYINKDTGAQ VTKNEAIAAS IAQENDKRSD QAVIVKVKIS RRAIAQSQSL
240 ESSRFETPMF QKFEASAAEL NKPADAPLIS DSNELTVIST SGFALENALS SVTAGMAFRE
300 ASIIPEDKES IINAEIKNKA LERLRKESIT SIKTLETIAS IVDDTLEKYK GAWFERNINK
360 HSHLNQDAAN ELVQNSWNAI KTKIIRRELR GYALTAGWSL HPIVENKDSS KYTPAQKRGI
420 REYVGSGYVD INNALLGLYN PDERTSILTA SDIEKAIDNL DSAFKNGERL PKGITLYRSQ
480 RMLPSIYEAM VKNRVFYFRN FVSTSLYPNI FGTWMTDSSI GVLPDEKRLS VSIDKTDEGL
540 VNSSDNLVGI GWVITGADKV NVVLPGGSLA PSNEMEVILP RGLMVKVNKI TDASYNDGTV
600 KTNNKLIQAE VMTTEELTES VIYDGDHLME TGELVTMTGD IEDRVDFASF VSSNVKQKVE
660 SSLGIIASCI DIANMPYKFV QG
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
4141
Hilse D.,Koch T.,Rueger W.
Nucleotide sequence of the alt gene of bacteriophage T4.
Nucleic Acids Res.
17
6731-6731
1989
4142
Koch T.,Rueger W.
The ADP-ribosyltransferases (gpAlt) of bacteriophages T2, T4, and T6: sequencing of the genes and comparison of their products.
Virology
203
294-298
1994
4143
Miller E.S.,Kutter E.,Mosig G.,Arisaka F.,Kunisawa T.,Ruger W.
Bacteriophage T4 genome.
Microbiol. Mol. Biol. Rev.
67
86-156
2003
4144
Horvitz H.R.
Bacteriophage T4 mutants deficient in alteration and modification of the Escherichia coli RNA polymerase.
J. Mol. Biol.
90
739-750
1974
4145
Goff C.G.
Bacteriophage T4 alt gene maps between genes 30 and 54.
J. Virol.
29
1232-1234
1979
4146
Wilkens K.,Tiemann B.,Bazan J.F.,Rueger W.
ADP-ribosylation and early transcription regulation by bacteriophage T4.
Adv. Exp. Med. Biol.
419
71-82
1997
4147
Rohrer H.,Zillig W.,Mailhammer R.
ADP-ribosylation of DNA-dependent RNA polymerase of Escherichia coli by an NAD+: protein ADP-ribosyltransferase from bacteriophage T4.
Eur. J. Biochem.
60
227-238
1975
4148
Sommer N.,Salniene V.,Gineikiene E.,Nivinskas R.,Rueger W.
T4 early promoter strength probed in vivo with unribosylated and ADP-ribosylated Escherichia coli RNA polymerase: a mutation analysis.
Microbiology
146
2643-2653
2000
4149
Depping R.,Lohaus C.,Meyer H.E.,Ruger W.
The mono-ADP-ribosyltransferases Alt and ModB of bacteriophage T4: target proteins identified.
Biochem. Biophys. Res. Commun.
335
1217-1223
2005
4150
Alawneh A.M.,Qi D.,Yonesaki T.,Otsuka Y.
An ADP-ribosyltransferase Alt of bacteriophage T4 negatively regulates the Escherichia coli MazF toxin of a toxin-antitoxin module.
Mol. Microbiol.
99
188-198
2016