Sequence of AT2A2_HUMAN

Ca2+-transporting ATPase

P16615

1042

114757

438479

Lytton J.,Maclennan D.H.

Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene.

J. Biol. Chem.

263

15024-15031

1988

438480

Scherer S.E.,Muzny D.M.,Buhay C.J.,Chen R.,Cree A.,Ding Y.,Dugan-Rocha S.,Gill R.,Gunaratne P.,Harris R.A.,Hawes A.C.,Hernandez J.,Hodgson A.V.,Hume J.,Jackson A.,Khan Z.M.,Kovar-Smith C.,Lewis L.R.,Lozado R.J.,Metzker M.L.,Milosavljevic A.,Miner G.R.,Montgomery K.T.,Morgan M.B.,Nazareth L.V.,Scott G.,Sodergren E.,Song X.-Z.,Steffen D.,Lovering R.C.,Wheeler D.A.,Worley K.C.,Yuan Y.,Zhang Z.,Adams C.Q.,Ansari-Lari M.A.,Ayele M.,Brown M.J.,Chen G.,Chen Z.,Clerc-Blankenburg K.P.,Davis C.,Delgado O.,Dinh H.H.,Draper H.,Gonzalez-Garay M.L.,Havlak P.,Jackson L.R.,Jacob L.S.,Kelly S.H.,Li L.,Li Z.,Liu J.,Liu W.,Lu J.,Maheshwari M.,Nguyen B.-V.,Okwuonu G.O.,Pasternak S.,Perez L.M.,Plopper F.J.H.,Santibanez J.,Shen H.,Tabor P.E.,Verduzco D.,Waldron L.,Wang Q.,Williams G.A.,Zhang J.,Zhou J.,Allen C.C.,Amin A.G.,Anyalebechi V.,Bailey M.,Barbaria J.A.,Bimage K.E.,Bryant N.P.,Burch P.E.,Burkett C.E.,Burrell K.L.,Calderon E.,Cardenas V.,Carter K.,Casias K.,Cavazos I.,Cavazos S.R.,Ceasar H.,Chacko J.,Chan S.N.,Chavez D.,Christopoulos C.,Chu J.,Cockrell R.,Cox C.D.,Dang M.,Dathorne S.R.,David R.,Davis C.M.,Davy-Carroll L.,Deshazo D.R.,Donlin J.E.,D'Souza L.,Eaves K.A.,Egan A.,Emery-Cohen A.J.,Escotto M.,Flagg N.,Forbes L.D.,Gabisi A.M.,Garza M.,Hamilton C.,Henderson N.,Hernandez O.,Hines S.,Hogues M.E.,Huang M.,Idlebird D.G.,Johnson R.,Jolivet A.,Jones S.,Kagan R.,King L.M.,Leal B.,Lebow H.,Lee S.,LeVan J.M.,Lewis L.C.,London P.,Lorensuhewa L.M.,Loulseged H.,Lovett D.A.,Lucier A.,Lucier R.L.,Ma J.,Madu R.C.,Mapua P.,Martindale A.D.,Martinez E.,Massey E.,Mawhiney S.,Meador M.G.,Mendez S.,Mercado C.,Mercado I.C.,Merritt C.E.,Miner Z.L.,Minja E.,Mitchell T.,Mohabbat F.,Mohabbat K.,Montgomery B.,Moore N.,Morris S.,Munidasa M.,Ngo R.N.,Nguyen N.B.,Nickerson E.,Nwaokelemeh O.O.,Nwokenkwo S.,Obregon M.,Oguh M.,Oragunye N.,Oviedo R.J.,Parish B.J.,Parker D.N.,Parrish J.,Parks K.L.,Paul H.A.,Payton B.A.,Perez A.,Perrin W.,Pickens A.,Primus E.L.,Pu L.-L.,Puazo M.,Quiles M.M.,Quiroz J.B.,Rabata D.,Reeves K.,Ruiz S.J.,Shao H.,Sisson I.,Sonaike T.,Sorelle R.P.,Sutton A.E.,Svatek A.F.,Svetz L.A.,Tamerisa K.S.,Taylor T.R.,Teague B.,Thomas N.,Thorn R.D.,Trejos Z.Y.,Trevino B.K.,Ukegbu O.N.,Urban J.B.,Vasquez L.I.,Vera V.A.,Villasana D.M.,Wang L.,Ward-Moore S.,Warren J.T.,Wei X.,White F.,Williamson A.L.,Wleczyk R.,Wooden H.S.,Wooden S.H.,Yen J.,Yoon L.,Yoon V.,Zorrilla S.E.,Nelson D.,Kucherlapati R.,Weinstock G.,Gibbs R.A.

The finished DNA sequence of human chromosome 12.

Nature

440

346-351

2006

438481

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

438482

Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet.

36

40-45

2004

438483

Gelebart P.,Martin V.,Enouf J.,Papp B.

Identification of a new SERCA2 splice variant regulated during monocytic differentiation.

Biochem. Biophys. Res. Commun.

303

676-684

2003

438484

Kiewitz R.,Acklin C.,Schaefer B.W.,Maco B.,Uhrik B.,Wuytack F.,Erne P.,Heizmann C.W.

Ca2+ -dependent interaction of S100A1 with the sarcoplasmic reticulum Ca2+ -ATPase2a and phospholamban in the human heart.

Biochem. Biophys. Res. Commun.

306

550-557

2003

438485

Stefanovic B.,Stefanovic L.,Schnabl B.,Bataller R.,Brenner D.A.

TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis.

Mol. Cell. Biol.

24

1758-1768

2004

438486

Xu S.,Ying J.,Jiang B.,Guo W.,Adachi T.,Sharov V.,Lazar H.,Menzoian J.,Knyushko T.V.,Bigelow D.,Schoeneich C.,Cohen R.A.

Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging.

Am. J. Physiol.

290

H2220-H2227

2006

438487

Olsen J.V.,Blagoev B.,Gnad F.,Macek B.,Kumar C.,Mortensen P.,Mann M.

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

Cell

127

635-648

2006

438488

Daub H.,Olsen J.V.,Bairlein M.,Gnad F.,Oppermann F.S.,Korner R.,Greff Z.,Keri G.,Stemmann O.,Mann M.

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

Mol. Cell

31

438-448

2008

438489

Dephoure N.,Zhou C.,Villen J.,Beausoleil S.A.,Bakalarski C.E.,Elledge S.J.,Gygi S.P.

A quantitative atlas of mitotic phosphorylation.

Proc. Natl. Acad. Sci. U.S.A.

105

10762-10767

2008

438490

Vafiadaki E.,Arvanitis D.A.,Pagakis S.N.,Papalouka V.,Sanoudou D.,Kontrogianni-Konstantopoulos A.,Kranias E.G.

The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival.

Mol. Biol. Cell

20

306-318

2009

438491

Mayya V.,Lundgren D.H.,Hwang S.-I.,Rezaul K.,Wu L.,Eng J.K.,Rodionov V.,Han D.K.

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

Sci. Signal.

2

RA46-RA46

2009

438492

Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.

Initial characterization of the human central proteome.

BMC Syst. Biol.

5

17-17

2011

438493

Krapivinsky G.,Krapivinsky L.,Stotz S.C.,Manasian Y.,Clapham D.E.

POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters.

Proc. Natl. Acad. Sci. U.S.A.

108

19234-19239

2011

438494

Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.

Toward a comprehensive characterization of a human cancer cell phosphoproteome.

J. Proteome Res.

12

260-271

2013

438495

Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

J. Proteomics

96

253-262

2014

438496

Shambharkar P.B.,Bittinger M.,Latario B.,Xiong Z.,Bandyopadhyay S.,Davis V.,Lin V.,Yang Y.,Valdez R.,Labow M.A.

TMEM203 is a novel regulator of intracellular calcium homeostasis and is required for spermatogenesis.

PLoS ONE

10

E0127480-E0127480

2015

438497

Vaca Jacome A.S.,Rabilloud T.,Schaeffer-Reiss C.,Rompais M.,Ayoub D.,Lane L.,Bairoch A.,Van Dorsselaer A.,Carapito C.

N-terminome analysis of the human mitochondrial proteome.

Proteomics

15

2519-2524

2015

438498

Raturi A.,Gutierrez T.,Ortiz-Sandoval C.,Ruangkittisakul A.,Herrera-Cruz M.S.,Rockley J.P.,Gesson K.,Ourdev D.,Lou P.H.,Lucchinetti E.,Tahbaz N.,Zaugg M.,Baksh S.,Ballanyi K.,Simmen T.

TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux.

J. Cell Biol.

214

433-444

2016

438499

Li A.,Yuen S.L.,Stroik D.R.,Kleinboehl E.,Cornea R.L.,Thomas D.D.

The transmembrane peptide DWORF activates SERCA2a via dual mechanisms.

J. Biol. Chem.

296

100412-100412

2021

438500

Phillips T.A.,Hauck G.T.,Pribadi M.P.,Cho E.E.,Cleary S.R.,Robia S.L.

Micropeptide hetero-oligomerization adds complexity to the calcium pump regulatory network.

Biophys. J.

122

301-309

2023

438501

Sakuntabhai A.,Burge S.,Monk S.,Hovnanian A.

Spectrum of novel ATP2A2 mutations in patients with Darier's disease.

Hum. Mol. Genet.

8

1611-1619

1999

438502

Ruiz-Perez V.L.,Carter S.A.,Healy E.,Todd C.,Rees J.L.,Steijlen P.M.,Carmichael A.J.,Lewis H.M.,Hohl D.,Itin P.,Vahlquist A.,Gobello T.,Mazzanti C.,Reggazini R.,Nagy G.,Munro C.S.,Strachan T.

ATP2A2 mutations in Darier's disease: variant cutaneous phenotypes are associated with missense mutations, but neuropsychiatric features are independent of mutation class.

Hum. Mol. Genet.

8

1621-1630

1999

438503

Jacobsen N.J.O.,Lyons I.,Hoogendoorn B.,Burge S.,Kwok P.-Y.,O'Donovan M.C.,Craddock N.,Owen M.J.

ATP2A2 mutations in Darier's disease and their relationship to neuropsychiatric phenotypes.

Hum. Mol. Genet.

8

1631-1636

1999

438504

Sakuntabhai A.,Ruiz-Perez V.,Carter S.,Jacobsen N.,Burge S.,Monk S.,Smith M.,Munro C.S.,O'Donovan M.C.,Craddock N.,Kucherlapati R.,Rees J.L.,Owen M.J.,Lathrop G.M.,Monaco A.P.,Strachan T.,Hovnanian A.

Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease.

Nat. Genet.

21

271-277

1999

438505

Dhitavat J.,Macfarlane S.,Dode L.,Leslie N.,Sakuntabhai A.,MacSween R.,Saihan E.,Hovnanian A.

Acrokeratosis verruciformis of Hopf is caused by mutation in ATP2A2: evidence that it is allelic to Darier's disease.

J. Invest. Dermatol.

120

229-232

2003

438506

Dally S.,Bredoux R.,Corvazier E.,Andersen J.P.,Clausen J.D.,Dode L.,Fanchaouy M.,Gelebart P.,Monceau V.,Del Monte F.,Gwathmey J.K.,Hajjar R.,Chaabane C.,Bobe R.,Raies A.,Enouf J.

Ca2+-ATPases in non-failing and failing heart: evidence for a novel cardiac sarco/endoplasmic reticulum Ca2+-ATPase 2 isoform (SERCA2c).

Biochem. J.

395

249-258

2006

438507

Zhao Y.G.,Chen Y.,Miao G.,Zhao H.,Qu W.,Li D.,Wang Z.,Liu N.,Li L.,Chen S.,Liu P.,Feng D.,Zhang H.

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.

Mol. Cell

67

974.e6-989.e6

2017

438508

Vandervore L.V.,Schot R.,Milanese C.,Smits D.J.,Kasteleijn E.,Fry A.E.,Pilz D.T.,Brock S.,Boerklue-Yuecel E.,Post M.,Bahi-Buisson N.,Sanchez-Soler M.J.,van Slegtenhorst M.,Keren B.,Afenjar A.,Coury S.A.,Tan W.H.,Oegema R.,de Vries L.S.,Fawcett K.A.,Nikkels P.G.J.,Bertoli-Avella A.,Al Hashem A.,Alwabel A.A.,Tlili-Graiess K.,Efthymiou S.,Zafar F.,Rana N.,Bibi F.,Houlden H.,Maroofian R.,Person R.E.,Crunk A.,Savatt J.M.,Turner L.,Doosti M.,Karimiani E.G.,Saadi N.W.,Akhondian J.,Lequin M.H.,Kayserili H.,van der Spek P.J.,Jansen A.C.,Kros J.M.,Verdijk R.M.,Milosevic N.J.,Fornerod M.,Mastroberardino P.G.,Mancini G.M.S.

TMX2 is a crucial regulator of cellular redox state, and its dysfunction causes severe brain developmental abnormalities.

Am. J. Hum. Genet.

105

1126-1147

2019

438509

Tsuruta D.,Akiyama M.,Ishida-Yamamoto A.,Imanishi H.,Mizuno N.,Sowa J.,Kobayashi H.,Ishii M.,Kurokawa I.,Shimizu H.

Three-base deletion mutation c.120_122delGTT in ATP2A2 leads to the unique phenotype of comedonal Darier disease.

Br. J. Dermatol.

162

687-689

2010

438510

Green E.K.,Gordon-Smith K.,Burge S.M.,Grozeva D.,Munro C.S.,Tavadia S.,Jones L.,Craddock N.

Novel ATP2A2 mutations in a large sample of individuals with Darier disease.

J. Dermatol.

40

259-266

2013

438511

Nellen R.G.,Steijlen P.M.,van Steensel M.A.,Vreeburg M.,Frank J.,van Geel M.

Mendelian Disorders of Cornification Caused by Defects in Intracellular Calcium Pumps: Mutation Update and Database for Variants in ATP2A2 and ATP2C1 associated with Darier disease and Hailey-Hailey disease.

Hum. Mutat.

38

343-356

2017