Sequence of KIF11_HUMAN

plus-end-directed kinesin ATPase

P52732

1056

119159

581283

Blangy A.,Lane H.A.,D'Herin P.,Harper M.,Kress M.,Nigg E.A.

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo.

Cell

83

1159-1169

1995

581284

Whitehead C.M.,Rattner J.B.

Expanding the role of HsEg5 within the mitotic and post-mitotic phases of the cell cycle.

J. Cell Sci.

111

2551-2561

1998

581285

Deloukas P.,Earthrowl M.E.,Grafham D.V.,Rubenfield M.,French L.,Steward C.A.,Sims S.K.,Jones M.C.,Searle S.,Scott C.,Howe K.,Hunt S.E.,Andrews T.D.,Gilbert J.G.R.,Swarbreck D.,Ashurst J.L.,Taylor A.,Battles J.,Bird C.P.,Ainscough R.,Almeida J.P.,Ashwell R.I.S.,Ambrose K.D.,Babbage A.K.,Bagguley C.L.,Bailey J.,Banerjee R.,Bates K.,Beasley H.,Bray-Allen S.,Brown A.J.,Brown J.Y.,Burford D.C.,Burrill W.,Burton J.,Cahill P.,Camire D.,Carter N.P.,Chapman J.C.,Clark S.Y.,Clarke G.,Clee C.M.,Clegg S.,Corby N.,Coulson A.,Dhami P.,Dutta I.,Dunn M.,Faulkner L.,Frankish A.,Frankland J.A.,Garner P.,Garnett J.,Gribble S.,Griffiths C.,Grocock R.,Gustafson E.,Hammond S.,Harley J.L.,Hart E.,Heath P.D.,Ho T.P.,Hopkins B.,Horne J.,Howden P.J.,Huckle E.,Hynds C.,Johnson C.,Johnson D.,Kana A.,Kay M.,Kimberley A.M.,Kershaw J.K.,Kokkinaki M.,Laird G.K.,Lawlor S.,Lee H.M.,Leongamornlert D.A.,Laird G.,Lloyd C.,Lloyd D.M.,Loveland J.,Lovell J.,McLaren S.,McLay K.E.,McMurray A.,Mashreghi-Mohammadi M.,Matthews L.,Milne S.,Nickerson T.,Nguyen M.,Overton-Larty E.,Palmer S.A.,Pearce A.V.,Peck A.I.,Pelan S.,Phillimore B.,Porter K.,Rice C.M.,Rogosin A.,Ross M.T.,Sarafidou T.,Sehra H.K.,Shownkeen R.,Skuce C.D.,Smith M.,Standring L.,Sycamore N.,Tester J.,Thorpe A.,Torcasso W.,Tracey A.,Tromans A.,Tsolas J.,Wall M.,Walsh J.,Wang H.,Weinstock K.,West A.P.,Willey D.L.,Whitehead S.L.,Wilming L.,Wray P.W.,Young L.,Chen Y.,Lovering R.C.,Moschonas N.K.,Siebert R.,Fechtel K.,Bentley D.,Durbin R.M.,Hubbard T.,Doucette-Stamm L.,Beck S.,Smith D.R.,Rogers J.

The DNA sequence and comparative analysis of human chromosome 10.

Nature

429

375-381

2004

581286

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

581287

Lee J.W.,Choi H.-S.,Gyuris J.,Brent R.,Moore D.D.

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

Mol. Endocrinol.

9

243-254

1995

581288

Beausoleil S.A.,Villen J.,Gerber S.A.,Rush J.,Gygi S.P.

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

Nat. Biotechnol.

24

1285-1292

2006

581289

Matsuoka S.,Ballif B.A.,Smogorzewska A.,McDonald E.R. III,Hurov K.E.,Luo J.,Bakalarski C.E.,Zhao Z.,Solimini N.,Lerenthal Y.,Shiloh Y.,Gygi S.P.,Elledge S.J.

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Science

316

1160-1166

2007

581290

Rapley J.,Nicolas M.,Groen A.,Regue L.,Bertran M.T.,Caelles C.,Avruch J.,Roig J.

The NIMA-family kinase Nek6 phosphorylates the kinesin Eg5 at a novel site necessary for mitotic spindle formation.

J. Cell Sci.

121

3912-3921

2008

581291

Dephoure N.,Zhou C.,Villen J.,Beausoleil S.A.,Bakalarski C.E.,Elledge S.J.,Gygi S.P.

A quantitative atlas of mitotic phosphorylation.

Proc. Natl. Acad. Sci. U.S.A.

105

10762-10767

2008

581292

Choudhary C.,Kumar C.,Gnad F.,Nielsen M.L.,Rehman M.,Walther T.C.,Olsen J.V.,Mann M.

Lysine acetylation targets protein complexes and co-regulates major cellular functions.

Science

325

834-840

2009

581293

Olsen J.V.,Vermeulen M.,Santamaria A.,Kumar C.,Miller M.L.,Jensen L.J.,Gnad F.,Cox J.,Jensen T.S.,Nigg E.A.,Brunak S.,Mann M.

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

Sci. Signal.

3

RA3-RA3

2010

581294

Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.

Initial characterization of the human central proteome.

BMC Syst. Biol.

5

17-17

2011

581295

Sahab Z.J.,Hall M.D.,Me Sung Y.,Dakshanamurthy S.,Ji Y.,Kumar D.,Byers S.W.

Tumor suppressor RARRES1 interacts with cytoplasmic carboxypeptidase AGBL2 to regulate the alpha-tubulin tyrosination cycle.

Cancer Res.

71

1219-1228

2011

581296

Rigbolt K.T.,Prokhorova T.A.,Akimov V.,Henningsen J.,Johansen P.T.,Kratchmarova I.,Kassem M.,Mann M.,Olsen J.V.,Blagoev B.

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

Sci. Signal.

4

RS3-RS3

2011

581297

Wakana Y.,Villeneuve J.,van Galen J.,Cruz-Garcia D.,Tagaya M.,Malhotra V.

Kinesin-5/Eg5 is important for transport of CARTS from the trans-Golgi network to the cell surface.

J. Cell Biol.

202

241-250

2013

581298

Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.

Toward a comprehensive characterization of a human cancer cell phosphoproteome.

J. Proteome Res.

12

260-271

2013

581299

Hendriks I.A.,Lyon D.,Young C.,Jensen L.J.,Vertegaal A.C.,Nielsen M.L.

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

Nat. Struct. Mol. Biol.

24

325-336

2017

581300

Qi X.,Liu Y.,Peng Y.,Fu Y.,Fu Y.,Yin L.,Li X.

UHRF1 promotes spindle assembly and chromosome congression by catalyzing EG5 polyubiquitination.

J. Cell Biol.

222

0-0

2023

581301

Turner J.,Anderson R.,Guo J.,Beraud C.,Fletterick R.,Sakowicz R.

Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker.

J. Biol. Chem.

276

25496-25502

2001

581302

Zhu P.,Zhou W.,Wang J.,Puc J.,Ohgi K.A.,Erdjument-Bromage H.,Tempst P.,Glass C.K.,Rosenfeld M.G.

A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation.

Mol. Cell

27

609-621

2007

581303

Ostergaard P.,Simpson M.A.,Mendola A.,Vasudevan P.,Connell F.C.,van Impel A.,Moore A.T.,Loeys B.L.,Ghalamkarpour A.,Onoufriadis A.,Martinez-Corral I.,Devery S.,Leroy J.G.,van Laer L.,Singer A.,Bialer M.G.,McEntagart M.,Quarrell O.,Brice G.,Trembath R.C.,Schulte-Merker S.,Makinen T.,Vikkula M.,Mortimer P.S.,Mansour S.,Jeffery S.

Mutations in KIF11 cause autosomal-dominant microcephaly variably associated with congenital lymphedema and chorioretinopathy.

Am. J. Hum. Genet.

90

356-362

2012