Sequence of UB2D1_HUMAN

ubiquitin-protein ligase

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UbcH5A, a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, a stimulator of iron transport, and is up-regulated in hereditary hemochromatosis.

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The DNA sequence and comparative analysis of human chromosome 10.

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577502

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Functional expression cloning and characterization of SFT, a stimulator of Fe transport.

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Matsuzawa S.,Reed J.C.

Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses.

Mol. Cell

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577506

Subramaniam V.,Li H.,Wong M.J.,Kitching R.,Attisano L.,Wrana J.,Zubovits J.,Burger A.M.,Seth A.K.

The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase.

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Hoeller D.,Hecker C.M.,Wagner S.,Rogov V.,Doetsch V.,Dikic I.

E3-independent monoubiquitination of ubiquitin-binding proteins.

Mol. Cell

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Windheim M.,Peggie M.,Cohen P.

Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology.

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Espinosa A.,Oke V.,Elfving A.,Nyberg F.,Covacu R.,Wahren-Herlenius M.

The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide.

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577510

Grou C.P.,Carvalho A.F.,Pinto M.P.,Wiese S.,Piechura H.,Meyer H.E.,Warscheid B.,Sa-Miranda C.,Azevedo J.E.

Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor.

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577511

Pabarcus M.K.,Hoe N.,Sadeghi S.,Patterson C.,Wiertz E.,Correia M.A.

CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases.

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2009

577512

Zeng W.,Xu M.,Liu S.,Sun L.,Chen Z.J.

Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3.

Mol. Cell

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577513

David Y.,Ziv T.,Admon A.,Navon A.

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

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577514

Sheng Y.,Hong J.H.,Doherty R.,Srikumar T.,Shloush J.,Avvakumov G.V.,Walker J.R.,Xue S.,Neculai D.,Wan J.W.,Kim S.K.,Arrowsmith C.H.,Raught B.,Dhe-Paganon S.

A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.

Mol. Cell. Proteomics

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577515

Zhang L.,Fairall L.,Goult B.T.,Calkin A.C.,Hong C.,Millard C.J.,Tontonoz P.,Schwabe J.W.

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.

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2011