Sequence of CBLB_HUMAN

ubiquitin-protein ligase

Q13191

982

109450

738238

Keane M.M.,Rivero-Lezcano O.M.,Mitchell J.A.,Robbins K.C.,Lipkowitz S.

Cloning and characterization of cbl-b: a SH3 binding protein with homology to the c-cbl proto-oncogene.

Oncogene

10

2367-2377

1995

738239

Bustelo X.R.,Crespo P.,Lopez-Barahona M.,Gutkind J.S.,Barbacid M.

Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation.

Oncogene

15

2511-2520

1997

738241

Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet.

36

40-45

2004

738242

Muzny D.M.,Scherer S.E.,Kaul R.,Wang J.,Yu J.,Sudbrak R.,Buhay C.J.,Chen R.,Cree A.,Ding Y.,Dugan-Rocha S.,Gill R.,Gunaratne P.,Harris R.A.,Hawes A.C.,Hernandez J.,Hodgson A.V.,Hume J.,Jackson A.,Khan Z.M.,Kovar-Smith C.,Lewis L.R.,Lozado R.J.,Metzker M.L.,Milosavljevic A.,Miner G.R.,Morgan M.B.,Nazareth L.V.,Scott G.,Sodergren E.,Song X.-Z.,Steffen D.,Wei S.,Wheeler D.A.,Wright M.W.,Worley K.C.,Yuan Y.,Zhang Z.,Adams C.Q.,Ansari-Lari M.A.,Ayele M.,Brown M.J.,Chen G.,Chen Z.,Clendenning J.,Clerc-Blankenburg K.P.,Chen R.,Chen Z.,Davis C.,Delgado O.,Dinh H.H.,Dong W.,Draper H.,Ernst S.,Fu G.,Gonzalez-Garay M.L.,Garcia D.K.,Gillett W.,Gu J.,Hao B.,Haugen E.,Havlak P.,He X.,Hennig S.,Hu S.,Huang W.,Jackson L.R.,Jacob L.S.,Kelly S.H.,Kube M.,Levy R.,Li Z.,Liu B.,Liu J.,Liu W.,Lu J.,Maheshwari M.,Nguyen B.-V.,Okwuonu G.O.,Palmeiri A.,Pasternak S.,Perez L.M.,Phelps K.A.,Plopper F.J.,Qiang B.,Raymond C.,Rodriguez R.,Saenphimmachak C.,Santibanez J.,Shen H.,Shen Y.,Subramanian S.,Tabor P.E.,Verduzco D.,Waldron L.,Wang J.,Wang J.,Wang Q.,Williams G.A.,Wong G.K.-S.,Yao Z.,Zhang J.,Zhang X.,Zhao G.,Zhou J.,Zhou Y.,Nelson D.,Lehrach H.,Reinhardt R.,Naylor S.L.,Yang H.,Olson M.,Weinstock G.,Gibbs R.A.

The DNA sequence, annotation and analysis of human chromosome 3.

Nature

440

1194-1198

2006

738244

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

738245

Ohira M.,Morohashi A.,Nakamura Y.,Isogai E.,Furuya K.,Hamano S.,Machida T.,Aoyama M.,Fukumura M.,Miyazaki K.,Suzuki Y.,Sugano S.,Hirato J.,Nakagawara A.

Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma.

Cancer Lett.

197

63-68

2003

738246

Bechtel S.,Rosenfelder H.,Duda A.,Schmidt C.P.,Ernst U.,Wellenreuther R.,Mehrle A.,Schuster C.,Bahr A.,Bloecker H.,Heubner D.,Hoerlein A.,Michel G.,Wedler H.,Koehrer K.,Ottenwaelder B.,Poustka A.,Wiemann S.,Schupp I.

The full-ORF clone resource of the German cDNA consortium.

BMC Genomics

8

399-399

2007

738247

Elly C.,Witte S.,Zhang Z.,Rosnet O.,Lipkowitz S.,Altman A.,Liu Y.-C.

Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation.

Oncogene

18

1147-1156

1999

738248

Ettenberg S.A.,Keane M.M.,Nau M.M.,Frankel M.,Wang L.-M.,Pierce J.H.,Lipkowitz S.

cbl-b inhibits epidermal growth factor receptor signaling.

Oncogene

18

1855-1866

1999

738249

Fang D.,Wang H.-Y.,Fang N.,Altman Y.,Elly C.,Liu Y.-C.

Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

J. Biol. Chem.

276

4872-4878

2001

738250

Ettenberg S.A.,Magnifico A.,Cuello M.,Nau M.M.,Rubinstein Y.R.,Yarden Y.,Weissman A.M.,Lipkowitz S.

Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex.

J. Biol. Chem.

276

27677-27684

2001

738251

Fang D.,Liu Y.-C.

Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.

Nat. Immunol.

2

870-875

2001

738252

Szymkiewicz I.,Kowanetz K.,Soubeyran P.,Dinarina A.,Lipkowitz S.,Dikic I.

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases.

J. Biol. Chem.

277

39666-39672

2002

738253

Kim M.,Tezuka T.,Tanaka K.,Yamamoto T.

Cbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradation.

Oncogene

23

1645-1655

2004

738254

Davies G.C.,Ettenberg S.A.,Coats A.O.,Mussante M.,Ravichandran S.,Collins J.,Nau M.M.,Lipkowitz S.

Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b.

Oncogene

23

7104-7115

2004

738255

Olsen J.V.,Blagoev B.,Gnad F.,Macek B.,Kumar C.,Mortensen P.,Mann M.

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

Cell

127

635-648

2006

738256

Dephoure N.,Zhou C.,Villen J.,Beausoleil S.A.,Bakalarski C.E.,Elledge S.J.,Gygi S.P.

A quantitative atlas of mitotic phosphorylation.

Proc. Natl. Acad. Sci. U.S.A.

105

10762-10767

2008

738257

Gruber T.,Hermann-Kleiter N.,Hinterleitner R.,Fresser F.,Schneider R.,Gastl G.,Penninger J.M.,Baier G.

PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation.

Sci. Signal.

2

RA30-RA30

2009

738258

Ryan P.E.,Sivadasan-Nair N.,Nau M.M.,Nicholas S.,Lipkowitz S.

The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme.

J. Biol. Chem.

285

23687-23698

2010

738259

Schmid F.M.,Schou K.B.,Vilhelm M.J.,Holm M.S.,Breslin L.,Farinelli P.,Larsen L.A.,Andersen J.S.,Pedersen L.B.,Christensen S.T.

IFT20 modulates ciliary PDGFRalpha signaling by regulating the stability of Cbl E3 ubiquitin ligases.

J. Cell Biol.

217

151-161

2018

738260

Janssen E.,Peters Z.,Alosaimi M.F.,Smith E.,Milin E.,Stafstrom K.,Wallace J.G.,Platt C.D.,Chou J.,El Ansari Y.S.,Al Farsi T.,Ameziane N.,Al-Ali R.,Calvo M.,Rocha M.E.,Bauer P.,Al-Sannaa N.A.,Al Sukaiti N.F.,Alangari A.A.,Bertoli-Avella A.M.,Geha R.S.

Immune dysregulation caused by homozygous mutations in CBLB.

J. Clin. Invest.

132

0-0

2022

738261

Jozic D.,Cardenes N.,Deribe Y.L.,Moncalian G.,Hoeller D.,Groemping Y.,Dikic I.,Rittinger K.,Bravo J.

Cbl promotes clustering of endocytic adaptor proteins.

Nat. Struct. Mol. Biol.

12

972-979

2005

738262

Moncalian G.,Cardenes N.,Deribe Y.L.,Spinola-Amilibia M.,Dikic I.,Bravo J.

Atypical polyproline recognition by the CMS N-terminal Src homology 3 domain.

J. Biol. Chem.

281

38845-38853

2006

738263

Peschard P.,Kozlov G.,Lin T.,Mirza I.A.,Berghuis A.M.,Lipkowitz S.,Park M.,Gehring K.

Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b.

Mol. Cell

27

474-485

2007