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Sequence of V5TDZ4_FISAU

EC Number:2.5.1.146

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
3-geranyl-3-[(Z)-2-isocyanoethenyl]indole synthase
V5TDZ4
Fischerella ambigua (strain UTEX 1903)
309
35115
Reaction
geranyl diphosphate + 3-[(Z)-2-isocyanoethenyl]-1H-indole = 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + diphosphate

General information:

Sequence
show sequence in fasta format
  0 MNDVNRIRTD IINVAKTFGA EYSEKVLDEV FQVFGEQFAD NSFMIRTSNK QPDKLGCYFR
 60 YHEEDESQLG LAWDIARKSG LLSDQGRPVD QLIPEICETF PIMADGVDFD VKHGLAKIWQ
120 SIKGVVPVQD AFKLSLPASV TTHSDFLKNH HLDALYAFGI DYHHSSVNLY FDTYHPKHHT
180 SEYYKNLLQD LQFQPPSDEL LELLTNNGEI ALTFNFASPR IERLCFYLPF LNREAVPQNL
240 LNPLLKKYIN EAPALVDNPG FILGWSFGPQ GGKGTYTKVD VDYHGRTVPL FMKVHSQPLP
300 KAADFALAQ
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
237788562
Hillwig M.L.,Zhu Q.,Liu X.
Biosynthesis of ambiguine indole alkaloids in cyanobacterium Fischerella ambigua.
ACS Chem. Biol.
9
372-377
2014
237788563
Micallef M.L.,Sharma D.,Bunn B.M.,Gerwick L.,Viswanathan R.,Moffitt M.C.
Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria.
BMC Microbiol.
14
213-213
2014
237788564
Li S.,Lowell A.N.,Yu F.,Raveh A.,Newmister S.A.,Bair N.,Schaub J.M.,Williams R.M.,Sherman D.H.
Hapalindole/ambiguine biogenesis is mediated by a cope rearrangement, C-C bond-forming cascade.
J. Am. Chem. Soc.
137
15366-15369
2015
237788566
Awakawa T.,Mori T.,Nakashima Y.,Zhai R.,Wong C.P.,Hillwig M.L.,Liu X.,Abe I.
Molecular Insight into the Mg2+ -Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.
Angew. Chem. Int. Ed.
57
6810-6813
2018