Sequence of TTLL4_HUMAN
EC Number:6.3.2.61
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + [tubulin]-(alpha-L-glutamyl-gamma-L-glutamyl)-L-glutamate + n L-glutamate = [tubulin]-(gamma-(poly-alpha-L-glutamyl)-L-glutamyl)-L-glutamate + n ADP + n phosphate
General information:
Sequence
0 MASAGTQHYS IGLRQKNSFK QSGPSGTVPA TPPEKPSEGR VWPQAHQQVK PIWKLEKKQV
60 ETLSAGLGPG LLGVPPQPAY FFCPSTLCSS GTTAVIAGHS SSCYLHSLPD LFNSTLLYRR
120 SSYRQKPYQQ LESFCLRSSP SEKSPFSLPQ KSLPVSLTAN KATSSMVFSM AQPMASSSTE
180 PYLCLAAAGE NPSGKSLASA ISGKIPSPLS SSYKPMLNNN SFMWPNSTPV PLLQTTQGLK
240 PVSPPKIQPV SWHHSGGTGD CAPQPVDHKV PKSIGTVPAD ASAHIALSTA SSHDTSTTSV
300 ASSWYNRNNL AMRAEPLSCA LDDSSDSQDP TKEIRFTEAV RKLTARGFEK MPRQGCQLEQ
360 SSFLNPSFQW NVLNRSRRWK PPAVNQQFPQ EDAGSVRRVL PGASDTLGLD NTVFCTKRIS
420 IHLLASHASG LNHNPACESV IDSSAFGEGK APGPPFPQTL GIANVATRLS SIQLGQSEKE
480 RPEEARELDS SDRDISSATD LQPDQAETED TEEELVDGLE DCCSRDENEE EEGDSECSSL
540 SAVSPSESVA MISRSCMEIL TKPLSNHEKV VRPALIYSLF PNVPPTIYFG TRDERVEKLP
600 WEQRKLLRWK MSTVTPNIVK QTIGRSHFKI SKRNDDWLGC WGHHMKSPSF RSIREHQKLN
660 HFPGSFQIGR KDRLWRNLSR MQSRFGKKEF SFFPQSFILP QDAKLLRKAW ESSSRQKWIV
720 KPPASARGIG IQVIHKWSQL PKRRPLLVQR YLHKPYLISG SKFDLRIYVY VTSYDPLRIY
780 LFSDGLVRFA SCKYSPSMKS LGNKFMHLTN YSVNKKNAEY QANADEMACQ GHKWALKALW
840 NYLSQKGVNS DAIWEKIKDV VVKTIISSEP YVTSLLKMYV RRPYSCHELF GFDIMLDENL
900 KPWVLEVNIS PSLHSSSPLD ISIKGQMIRD LLNLAGFVLP NAEDIISSPS SCSSSTTSLP
960 TSPGDKCRMA PEHVTAQKMK KAYYLTQKIP DQDFYASVLD VLTPDDVRIL VEMEDEFSRR
1020 GQFERIFPSH ISSRYLRFFE QPRYFNILTT QWEQKYHGNK LKGVDLLRSW CYKGFHMGVV
1080 SDSAPVWSLP TSLLTISKDD VILNAFSKSE TSKLGKQSSC EVSLLLSEDG TTPKSKKTQA
1140 GLSPYPQKPS SSKDSEDTSK EPSLSTQTLP VIKCSGQTSR LSASSTFQSI SDSLLAVSP
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
747103
Nagase T.,Seki N.,Ishikawa K.,Tanaka A.,Nomura N.
Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.
DNA Res.
3
17-24
1996
747104
Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet.
36
40-45
2004
747106
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
747107
Mayya V.,Lundgren D.H.,Hwang S.-I.,Rezaul K.,Wu L.,Eng J.K.,Rodionov V.,Han D.K.
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Sci. Signal.
2
RA46-RA46
2009
747108
Garnham C.P.,Vemu A.,Wilson-Kubalek E.M.,Yu I.,Szyk A.,Lander G.C.,Milligan R.A.,Roll-Mecak A.
Multivalent microtubule recognition by tubulin tyrosine ligase-like family glutamylases.
Cell
161
1112-1123
2015
