Sequence of TTLL6_MOUSE

tubulin-glutamate ligase

A4Q9E8

822

94507

51238

van Dijk J.,Rogowski K.,Miro J.,Lacroix B.,Edde B.,Janke C.

A targeted multienzyme mechanism for selective microtubule polyglutamylation.

Mol. Cell

26

437-448

2007

51239

Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.

The transcriptional landscape of the mammalian genome.

Science

309

1559-1563

2005

51240

Church D.M.,Goodstadt L.,Hillier L.W.,Zody M.C.,Goldstein S.,She X.,Bult C.J.,Agarwala R.,Cherry J.L.,DiCuccio M.,Hlavina W.,Kapustin Y.,Meric P.,Maglott D.,Birtle Z.,Marques A.C.,Graves T.,Zhou S.,Teague B.,Potamousis K.,Churas C.,Place M.,Herschleb J.,Runnheim R.,Forrest D.,Amos-Landgraf J.,Schwartz D.C.,Cheng Z.,Lindblad-Toh K.,Eichler E.E.,Ponting C.P.

Lineage-specific biology revealed by a finished genome assembly of the mouse.

PLoS Biol.

7

E1000112-E1000112

2009

51241

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

51242

Rogowski K.,van Dijk J.,Magiera M.M.,Bosc C.,Deloulme J.C.,Bosson A.,Peris L.,Gold N.D.,Lacroix B.,Grau M.B.,Bec N.,Larroque C.,Desagher S.,Holzer M.,Andrieux A.,Moutin M.J.,Janke C.

A family of protein-deglutamylating enzymes associated with neurodegeneration.

Cell

143

564-578

2010

51243

Lacroix B.,van Dijk J.,Gold N.D.,Guizetti J.,Aldrian-Herrada G.,Rogowski K.,Gerlich D.W.,Janke C.

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing.

J. Cell Biol.

189

945-954

2010

51244

Lee J.E.,Silhavy J.L.,Zaki M.S.,Schroth J.,Bielas S.L.,Marsh S.E.,Olvera J.,Brancati F.,Iannicelli M.,Ikegami K.,Schlossman A.M.,Merriman B.,Attie-Bitach T.,Logan C.V.,Glass I.A.,Cluckey A.,Louie C.M.,Lee J.H.,Raynes H.R.,Rapin I.,Castroviejo I.P.,Setou M.,Barbot C.,Boltshauser E.,Nelson S.F.,Hildebrandt F.,Johnson C.A.,Doherty D.A.,Valente E.M.,Gleeson J.G.

CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium.

Nat. Genet.

44

193-199

2012

51245

Bosch Grau M.,Gonzalez Curto G.,Rocha C.,Magiera M.M.,Marques Sousa P.,Giordano T.,Spassky N.,Janke C.

Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia.

J. Cell Biol.

202

441-451

2013

51246

Xia P.,Ye B.,Wang S.,Zhu X.,Du Y.,Xiong Z.,Tian Y.,Fan Z.

Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity.

Nat. Immunol.

17

369-378

2016

51247

Mahalingan K.K.,Keith Keenan E.,Strickland M.,Li Y.,Liu Y.,Ball H.L.,Tanner M.E.,Tjandra N.,Roll-Mecak A.

Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.

Nat. Struct. Mol. Biol.

27

802-813

2020