Sequence of TYLM1_STRFR
EC Number:2.1.1.235
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
P95748
Streptomyces fradiae
255
27428
Reaction
2 S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose = 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-glucopyranose
Other sequences found for EC No. 2.1.1.235
General information:
Sequence
0 MAHSSATAGP QADYSGEIAE LYDLVHQGKG KDYHREAADL AALVRRHSPK AASLLDVACG
60 TGMHLRHLAD SFGTVEGLEL SADMLAIARR RNPDAVLHHG DMRDFSLGRR FSAVTCMFSS
120 IGHLAGQAEL DAALERFAAH VLPDGVVVVE PWWFPENFTP GYVAAGTVEA GGTTVTRVSH
180 SSREGEATRI EVHYLVAGPD RGITHHEESH RITLFTREQY ERAFTAAGLS VEFMPGGPSG
240 RGLFTGLPGA KGETR
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
113407
Gandecha A.R.,Large S.L.,Cundliffe E.
Analysis of four tylosin biosynthetic genes from the tylLM region of Streptomyces fradiae.
Gene
184
197-203
1997
113408
Chen H.,Yamase H.,Murakami K.,Chang C.W.,Zhao L.,Zhao Z.,Liu H.W.
Expression, purification, and characterization of two N,N-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamine.
Biochemistry
41
9165-9183
2002
113409
Carney A.E.,Holden H.M.
Molecular architecture of TylM1 from Streptomyces fradiae: an N,N-dimethyltransferase involved in the production of dTDP-D-mycaminose.
Biochemistry
50
780-787
2011