Sequence of ALG44_PSEAE
EC Number:2.4.1.33
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
mannuronan synthase
Q9HY69
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
389
41787
Reaction
GDP-alpha-D-mannuronate + [(1->4)-beta-D-mannuronosyl]n = GDP + [(1->4)-beta-D-mannuronosyl]n+1
General information:
Sequence
0 MNTAVNVNVV HESEAQRQFA RVKLPARIRY IGANREGVDA RLLDLSAGGF AFTASGAPIQ
60 PGDLYKGKLL FQVDSISFSL EVEFQVRSVD PASRRVGCEF QNLKPREVAA LRYLITSYLA
120 GEVIGVGDML NTLQRENFTK ARKQGGGNGG MGFFGRVRAV TLSTAIFVVG VGAFAFILNQ
180 MYNLYFVTHA DSGVVSVPNQ QITMPREGTV QSLLGPNAEV AKGAPIATFS ANLLDMLKGN
240 LTEEQLNPGN IEKLFGHQMK GTLTSPCDCR VVQQLVADGQ YANKGQVIFT LAPRDSVASI
300 EARFPYRNAA ELAPGTRVNF QVAGDGVNRS GRIVNTAPVD GDLSSEIRVQ IQPDQPLDAQ
360 YAGRPAEVSI GGLPGRTLLN KAVTLATAR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1213208
Maharaj R.,May T.B.,Wang S.-K.,Chakrabarty A.M.
Sequence of the alg8 and alg44 genes involved in the synthesis of alginate by Pseudomonas aeruginosa.
Gene
136
267-269
1993
1213209
Stover C.K.,Pham X.-Q.T.,Erwin A.L.,Mizoguchi S.D.,Warrener P.,Hickey M.J.,Brinkman F.S.L.,Hufnagle W.O.,Kowalik D.J.,Lagrou M.,Garber R.L.,Goltry L.,Tolentino E.,Westbrock-Wadman S.,Yuan Y.,Brody L.L.,Coulter S.N.,Folger K.R.,Kas A.,Larbig K.,Lim R.M.,Smith K.A.,Spencer D.H.,Wong G.K.-S.,Wu Z.,Paulsen I.T.,Reizer J.,Saier M.H. Jr.,Hancock R.E.W.,Lory S.,Olson M.V.
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.
Nature
406
959-964
2000
1213211
Remminghorst U.,Rehm B.H.A.
Alg44, a unique protein required for alginate biosynthesis in Pseudomonas aeruginosa.
FEBS Lett.
580
3883-3888
2006
1213212
Oglesby L.L.,Jain S.,Ohman D.E.
Membrane topology and roles of Pseudomonas aeruginosa Alg8 and Alg44 in alginate polymerization.
Microbiology
154
1605-1615
2008
