Sequence of DDX1_HUMAN
EC Number:3.6.4.13
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
a nucleoside triphosphate + H2O = a nucleoside diphosphate + phosphate
Other sequences found for EC No. 3.6.4.13
General information:
Sequence
0 MAAFSEMGVM PEIAQAVEEM DWLLPTDIQA ESIPLILGGG DVLMAAETGS GKTGAFSIPV
60 IQIVYETLKD QQEGKKGKTT IKTGASVLNK WQMNPYDRGS AFAIGSDGLC CQSREVKEWH
120 GCRATKGLMK GKHYYEVSCH DQGLCRVGWS TMQASLDLGT DKFGFGFGGT GKKSHNKQFD
180 NYGEEFTMHD TIGCYLDIDK GHVKFSKNGK DLGLAFEIPP HMKNQALFPA CVLKNAELKF
240 NFGEEEFKFP PKDGFVALSK APDGYIVKSQ HSGNAQVTQT KFLPNAPKAL IVEPSRELAE
300 QTLNNIKQFK KYIDNPKLRE LLIIGGVAAR DQLSVLENGV DIVVGTPGRL DDLVSTGKLN
360 LSQVRFLVLD EADGLLSQGY SDFINRMHNQ IPQVTSDGKR LQVIVCSATL HSFDVKKLSE
420 KIMHFPTWVD LKGEDSVPDT VHHVVVPVNP KTDRLWERLG KSHIRTDDVH AKDNTRPGAN
480 SPEMWSEAIK ILKGEYAVRA IKEHKMDQAI IFCRTKIDCD NLEQYFIQQG GGPDKKGHQF
540 SCVCLHGDRK PHERKQNLER FKKGDVRFLI CTDVAARGID IHGVPYVINV TLPDEKQNYV
600 HRIGRVGRAE RMGLAISLVA TEKEKVWYHV CSSRGKGCYN TRLKEDGGCT IWYNEMQLLS
660 EIEEHLNCTI SQVEPDIKVP VDEFDGKVTY GQKRAAGGGS YKGHVDILAP TVQELAALEK
720 EAQTSFLHLG YLPNQLFRTF
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1176892
Godbout R.,Squire J.
Amplification of a DEAD box protein gene in retinoblastoma cell lines.
Proc. Natl. Acad. Sci. U.S.A.
90
7578-7582
1993
1176893
Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet.
36
40-45
2004
1176894
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
1176895
Bleoo S.,Sun X.,Hendzel M.J.,Rowe J.M.,Packer M.,Godbout R.
Association of human DEAD box protein DDX1 with a cleavage stimulation factor involved in 3'-end processing of pre-MRNA.
Mol. Biol. Cell
12
3046-3059
2001
1176896
Chen H.C.,Lin W.C.,Tsay Y.G.,Lee S.C.,Chang C.J.
An RNA helicase, DDX1, interacting with poly(A) RNA and heterogeneous nuclear ribonucleoprotein K.
J. Biol. Chem.
277
40403-40409
2002
1176897
Andersen J.S.,Wilkinson C.J.,Mayor T.,Mortensen P.,Nigg E.A.,Mann M.
Proteomic characterization of the human centrosome by protein correlation profiling.
Nature
426
570-574
2003
1176898
Fang J.,Kubota S.,Yang B.,Zhou N.,Zhang H.,Godbout R.,Pomerantz R.J.
A DEAD box protein facilitates HIV-1 replication as a cellular co-factor of Rev.
Virology
330
471-480
2004
1176899
Onishi H.,Kino Y.,Morita T.,Futai E.,Sasagawa N.,Ishiura S.
MBNL1 associates with YB-1 in cytoplasmic stress granules.
J. Neurosci. Res.
86
1994-2002
2008
1176900
Li L.,Monckton E.A.,Godbout R.
A role for DEAD box 1 at DNA double-strand breaks.
Mol. Cell. Biol.
28
6413-6425
2008
1176901
Ishaq M.,Ma L.,Wu X.,Mu Y.,Pan J.,Hu J.,Hu T.,Fu Q.,Guo D.
The DEAD-box RNA helicase DDX1 interacts with RelA and enhances nuclear factor kappaB-mediated transcription.
J. Cell. Biochem.
106
296-305
2009
1176902
Choudhary C.,Kumar C.,Gnad F.,Nielsen M.L.,Rehman M.,Walther T.C.,Olsen J.V.,Mann M.
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Science
325
834-840
2009
1176903
Xu L.,Khadijah S.,Fang S.,Wang L.,Tay F.P.,Liu D.X.
The cellular RNA helicase DDX1 interacts with coronavirus nonstructural protein 14 and enhances viral replication.
J. Virol.
84
8571-8583
2010
1176904
Olsen J.V.,Vermeulen M.,Santamaria A.,Kumar C.,Miller M.L.,Jensen L.J.,Gnad F.,Cox J.,Jensen T.S.,Nigg E.A.,Brunak S.,Mann M.
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
Sci. Signal.
3
0-0
2010
1176905
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
1176906
Kunde S.A.,Musante L.,Grimme A.,Fischer U.,Mueller E.,Wanker E.E.,Kalscheuer V.M.
The X-chromosome-linked intellectual disability protein PQBP1 is a component of neuronal RNA granules and regulates the appearance of stress granules.
Hum. Mol. Genet.
20
4916-4931
2011
1176907
Garbelli A.,Beermann S.,Di Cicco G.,Dietrich U.,Maga G.
A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication.
PLoS ONE
6
0-0
2011
1176908
Rigbolt K.T.,Prokhorova T.A.,Akimov V.,Henningsen J.,Johansen P.T.,Kratchmarova I.,Kassem M.,Mann M.,Olsen J.V.,Blagoev B.
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
Sci. Signal.
4
0-0
2011
1176909
Popow J.,Englert M.,Weitzer S.,Schleiffer A.,Mierzwa B.,Mechtler K.,Trowitzsch S.,Will C.L.,Luhrmann R.,Soll D.,Martinez J.
HSPC117 is the essential subunit of a human tRNA splicing ligase complex.
Science
331
760-764
2011
1176910
Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
J. Proteome Res.
12
260-271
2013
1176911
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
1176912
Popow J.,Jurkin J.,Schleiffer A.,Martinez J.
Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors.
Nature
511
104-107
2014
1176913
Perez-Gonzalez A.,Pazo A.,Navajas R.,Ciordia S.,Rodriguez-Frandsen A.,Nieto A.
hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.
PLoS ONE
9
0-0
2014
1176914
Nicolai S.,Filippi S.,Caputo M.,Cipak L.,Gregan J.,Ammerer G.,Frontini M.,Willems D.,Prantera G.,Balajee A.S.,Proietti-De-Santis L.
Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.
PLoS ONE
10
0-0
2015
1176915
Vaca Jacome A.S.,Rabilloud T.,Schaeffer-Reiss C.,Rompais M.,Ayoub D.,Lane L.,Bairoch A.,Van Dorsselaer A.,Carapito C.
N-terminome analysis of the human mitochondrial proteome.
Proteomics
15
2519-2524
2015
1176916
Amaya M.,Brooks-Faulconer T.,Lark T.,Keck F.,Bailey C.,Raman V.,Narayanan A.
Venezuelan equine encephalitis virus non-structural protein 3 (nsP3) interacts with RNA helicases DDX1 and DDX3 in infected cells.
Antiviral Res.
131
49-60
2016
1176917
Akter K.A.,Mansour M.A.,Hyodo T.,Senga T.
FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression.
Int. J. Biochem. Cell Biol.
84
1-13
2017
1176918
Hendriks I.A.,Lyon D.,Young C.,Jensen L.J.,Vertegaal A.C.,Nielsen M.L.
Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
Nat. Struct. Mol. Biol.
24
325-336
2017
1176919
Kellner J.N.,Meinhart A.
Structure of the SPRY domain of the human RNA helicase DDX1, a putative interaction platform within a DEAD-box protein.
Acta Crystallogr. F
71
1176-1188
2015
