Sequence of IP3KA_HUMAN

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
inositol-trisphosphate 3-kinase
P23677
Homo sapiens
461
51009
Reaction
ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MTLPGGPTGM ARPGGARPCS PGLERAPRRS VGELRLLFEA RCAAVAAAAA AGEPRARGAK
 60 RRGGQVPNGL PRAPPAPVIP QLTVTAEEPD VPPTSPGPPE RERDCLPAAG SSHLQQPRRL
120 STSSVSSTGS SSLLEDSEDD LLSDSESRSR GNVQLEAGED VGQKNHWQKI RTMVNLPVIS
180 PFKKRYAWVQ LAGHTGSFKA AGTSGLILKR CSEPERYCLA RLMADALRGC VPAFHGVVER
240 DGESYLQLQD LLDGFDGPCV LDCKMGVRTY LEEELTKARE RPKLRKDMYK KMLAVDPEAP
300 TEEEHAQRAV TKPRYMQWRE GISSSTTLGF RIEGIKKADG SCSTDFKTTR SREQVLRVFE
360 EFVQGDEEVL RRYLNRLQQI RDTLEVSEFF RRHEVIGSSL LFVHDHCHRA GVWLIDFGKT
420 TPLPDGQILD HRRPWEEGNR EDGYLLGLDN LIGILASLAE R
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1162962
Takazawa K.,Perret J.,Dumont J.E.,Erneux C.
Molecular cloning and expression of a human brain inositol 1,4,5-trisphosphate 3-kinase.
Biochem. Biophys. Res. Commun.
174
529-535
1991
1162963
Takazawa K.,Perret J.,Dumont J.E.,Erneux C.
Human brain inositol 1,4,5-trisphosphate 3-kinase cDNA sequence.
Nucleic Acids Res.
18
7141-7141
1990
1162964
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
1162965
Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
J. Proteome Res.
12
260-271
2013
1162966
Gonzalez B.,Schell M.J.,Letcher A.J.,Veprintsev D.B.,Irvine R.F.,Williams R.L.
Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase.
Mol. Cell
15
689-701
2004