Sequence of NDHL_PAENI
EC Number:1.5.99.4
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(S)-nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor
General information:
Sequence
0 MDNPHYYSPP ITRNVIGKRV PRTEDARLLT GRGKYLNDIN VDGQLHACFV RSPAAHAQIT
60 GIDTSAASEM PGVHLVWTSA DIEQYCAGIE AQYTAEGCEA MTMPLLAKDV VRYVGEPVVL
120 VVAESRAAAE DACDLVGLEL EHLEVVLDPR KSIQGGPVAN GERPDNVGIR GRASFGDVDE
180 AFSNAEHVVS ALYHPGRVAA APMETRGCLA DYEWTEDRLK LWVSTQMPHY VKMCLSLFLG
240 FDESRSEVIS PDTGGGFGQK AHVFPEEMLM PLASKHLKTP VKWVEDRREN LLAGSHAHEQ
300 FVTIQYAANA EGRITGVRTH ALVDGGAYHM PPQTMAVECW ATAAVTPTGV YDIPAAEYVY
360 EGAVTNKCPM GAFRGVGYTA GTLARESLMD DLARKMKVSP FEIRRRNVVR EFPWTNPQGV
420 VYEEGSFLEV IDALEEMVDY PAFLRRQDEA RKAGKYLGLG ISVFVESSGE STGMMQAHGA
480 TDVFHDTATV KMDSTGSVTI TSGLNSQGQG HQTTLAQVAA DVLGIPFESI SVDAGTSTKG
540 AYGSGTIGSR AAVIAGGCVN RAAYAIRQKL VAVAANMLES SEEDIVLEDG FASVIGAAES
600 RVSIADVAMA VYWDSSKWPA GFEPGLEFTK AWDTSRPMFS NGGHALIVEL DPVTGFVKVE
660 KVYSVEDCGV IINPTIVEGQ IRGGVVQGIG MGLFEQLAYD NAGNLSTTSF LDYQTPTMDV
720 SPPFEIRHIE TPSVMTASGV KGMGESGLIS APAAVLNAVN DALSPFGSVL YELPATPEKV
780 VRATKGIIDL QGPQDWSELW ERAGVPALDR GPMDRE
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1128750
Grether-Beck S.,Igloi G.L.,Pust S.,Schiltz E.,Decker K.,Brandsch R.
Structural analysis and molybdenum-dependent expression of the pAO1-encoded nicotine dehydrogenase genes of Arthrobacter nicotinovorans.
Mol. Microbiol.
13
929-936
1994
1128751
Baitsch D.,Sandu C.,Brandsch R.,Igloi G.L.
Gene cluster on pAO1 of Arthrobacter nicotinovorans involved in degradation of the plant alkaloid nicotine: cloning, purification, and characterization of 2,6-dihydroxypyridine 3-hydroxylase.
J. Bacteriol.
183
5262-5267
2001
1128752
Igloi G.L.,Brandsch R.
Sequence of the 165-kilobase catabolic plasmid pAO1 from Arthrobacter nicotinovorans and identification of a pAO1-dependent nicotine uptake system.
J. Bacteriol.
185
1976-1986
2003
1128753
Decker K.,Bleeg H.
Induction and purification of stereospecific nicotine oxidizing enzymes from Arthrobacter oxidans.
Biochim. Biophys. Acta
105
313-324
1965
1128754
Gurusamy R.,Natarajan S.
Current status on biochemistry and molecular biology of microbial degradation of nicotine.
ScientificWorldJournal
2013
125385-125385
2013
