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Sequence of ZDH17_MOUSE

EC Number:2.3.1.225

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2.3.1.225
protein S-acyltransferase
Q80TN5
Mus musculus
632
72621
Swiss-Prot
Reaction
palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA
Other sequences found for EC No. 2.3.1.225

General information:

Sequence
show sequence in fasta format
  0 MQREEGFNTK MADGPDEYET ETGCVPLLHP EEIKPQSHYN HGYGEPLGRK THIDDYSTWD
 60 IVKATQYGIY ERCRELVEAG YDVRQPDKEN VTLLHWAAIN NRIDLVKYYI SKGAIVDQLG
120 GDLNSTPLHW ATRQGHLSMV VQLMKYGADP SLIDGEGCSC IHLAAQFGHT SIVAYLIAKG
180 QDVDMMDQNG MTPLMWAAYR THSVDPTRLL LTFNVSVNLG DKYHKNTALH WAVLAGNTTV
240 ISLLLEAGGN VDAQNVKGES ALDLAKQRKN VWMINHLQEA RQAKGYDNPS FLRKLKADKE
300 FRQKVMLGTP FLVIWLVGFI ADLDIDSWLI KGLMYGGVWA TVQFLSKSFF DHSMHSALPL
360 GIYLATKFWM YVTWFFWFWN DLNFLFIHLP FLANSVALFY NFGKSWKSDP GIIKATEEQK
420 KKTIVELAET GSLDLSIFCS TCLIRKPVRS KHCGVCNRCI AKFDHHCPWV GNCVGAGNHR
480 YFMGYLFFLL FMICWMIYGC VSYWGLHCET TYTKDGFWTY ITQIATCSPW MFWMFLNSVF
540 HFLWVAVLLM CQLYQITCLG ITTNERMNAR RYKHFKVTTT SIESPFNHGC VRNIIDFFEF
600 RCCGLFRPVI VDWTRQYTIE YDQISGSGYQ LV
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1150883
Okazaki N.,Kikuno R.,Ohara R.,Inamoto S.,Aizawa H.,Yuasa S.,Nakajima D.,Nagase T.,Ohara O.,Koga H.
Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
DNA Res.
10
35-48
2003
12693553
1150884
Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.
The transcriptional landscape of the mammalian genome.
Science
309
1559-1563
2005
16141072
1150885
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
15489334
1150886
Singaraja R.R.,Hadano S.,Metzler M.,Givan S.,Wellington C.L.,Warby S.,Yanai A.,Gutekunst C.-A.,Leavitt B.R.,Yi H.,Fichter K.,Gan L.,McGutcheon K.,Chopra V.,Michel J.,Hersch S.M.,Ikeda J.E.,Hayden M.R.
HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis.
Hum. Mol. Genet.
11
2815-2828
2002
12393793
1150887
Fukata M.,Fukata Y.,Adesnik H.,Nicoll R.A.,Bredt D.S.
Identification of PSD-95 palmitoylating enzymes.
Neuron
44
987-996
2004
15603741
1150888
Ducker C.E.,Stettler E.M.,French K.J.,Upson J.J.,Smith C.D.
Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase.
Oncogene
23
9230-9237
2004
15489887
1150889
Greaves J.,Salaun C.,Fukata Y.,Fukata M.,Chamberlain L.H.
Palmitoylation and membrane interactions of the neuroprotective chaperone cysteine-string protein.
J. Biol. Chem.
283
25014-25026
2008
18596047
1150890
Goytain A.,Hines R.M.,Quamme G.A.
Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport.
J. Biol. Chem.
283
33365-33374
2008
18794299
1150891
Butland S.L.,Sanders S.S.,Schmidt M.E.,Riechers S.P.,Lin D.T.,Martin D.D.,Vaid K.,Graham R.K.,Singaraja R.R.,Wanker E.E.,Conibear E.,Hayden M.R.
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.
Hum. Mol. Genet.
23
4142-4160
2014
24705354
1150892
Lemonidis K.,Gorleku O.A.,Sanchez-Perez M.C.,Grefen C.,Chamberlain L.H.
The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity.
Mol. Biol. Cell
25
3870-3883
2014
25253725
1150893
Lemonidis K.,Sanchez-Perez M.C.,Chamberlain L.H.
Identification of a novel sequence motif recognized by the ankyrin repeat domain of zDHHC17/13 S-acyltransferases.
J. Biol. Chem.
290
21939-21950
2015
26198635
1150894
Shi W.,Wang F.,Gao M.,Yang Y.,Du Z.,Wang C.,Yao Y.,He K.,Chen X.,Hao A.
ZDHHC17 promotes axon outgrowth by regulating TrkA-tubulin complex formation.
Mol. Cell. Neurosci.
68
194-202
2015
26232532
1150895
Skotte N.H.,Sanders S.S.,Singaraja R.R.,Ehrnhoefer D.E.,Vaid K.,Qiu X.,Kannan S.,Verma C.,Hayden M.R.
Palmitoylation of caspase-6 by HIP14 regulates its activation.
Cell Death Differ.
24
433-444
2017
27911442
1150896
Lemonidis K.,MacLeod R.,Baillie G.S.,Chamberlain L.H.
Peptide array based screening reveals a large number of proteins interacting with the ankyrin repeat domain of the zDHHC17 S-acyltransferase.
J. Biol. Chem.
292
17190-17202
2017
28882895
1150897
Greaves J.,Munro K.R.,Davidson S.C.,Riviere M.,Wojno J.,Smith T.K.,Tomkinson N.C.,Chamberlain L.H.
Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry.
Proc. Natl. Acad. Sci. U.S.A.
114
0-0
2017
28167757