Sequence of VM1AD_CROAT
EC Number:3.4.24.42
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Cleavage of His5-/-Leu, His10-/-Leu, Ala14-/-Leu, Tyr16-/-Leu and Gly23-/-Phe bonds in B chain of insulin. With small molecule substrates prefers hydrophobic residue at P2' and small residue such as Ala, Gly at P1
Other sequences found for EC No. 3.4.24.42
General information:
Sequence
0 MIEVLLVTIC LAVFPYQGSS IILESGNVND YEVVYPRKVT ALPKGAVQPK YEDAMQYELK
60 VNGEPVVLHL EKNKELFSKD YSETHYSPDG RKITTNPSVE DHCYYRGRIE NDADSTASIS
120 ACNGLKGHFK LQGEMYLIEP LELSDSEAHA VFKLENVEKE DEAPKMCGVT QNWESYEPIK
180 KASDLNLNPD QQNLPQRYIE LVVVADHRVF MKYNSDLNTI RTRVHEIVNF INGFYRSLNI
240 HVSLTDLEIW SNEDQINIQS ASSDTLNAFA EWRETDLLNR KSHDNAQLLT AIELDEETLG
300 LAPLGTMCDP KLSIGIVQDH SPINLLMGVT MAHELGHNLG MEHDGKDCLR GASLCIMRPG
360 LTKGRSYEFS DDSMHYYERF LKQYKPQCIL NKPLRIDPVS TPVSGNELLE AGEE
Download this sequence
in fasta formatDownload all sequences for 3.4.24.42
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1142180
Hite L.A.,Jia L.-G.,Bjarnason J.B.,Fox J.W.
cDNA sequences for four snake venom metalloproteinases: structure, classification, and their relationship to mammalian reproductive proteins.
Arch. Biochem. Biophys.
308
182-191
1994
1142181
Shannon J.D.,Baramova E.N.,Bjarnason J.B.,Fox J.W.
Amino acid sequence of a Crotalus atrox venom metalloproteinase which cleaves type IV collagen and gelatin.
J. Biol. Chem.
264
11575-11583
1989
1142183
Calvete J.J.,Fasoli E.,Sanz L.,Boschetti E.,Righetti P.G.
Exploring the venom proteome of the western diamondback rattlesnake, Crotalus atrox, via snake venomics and combinatorial peptide ligand library approaches.
J. Proteome Res.
8
3055-3067
2009
1142184
Baramova E.N.,Shannon J.D.,Bjarnason J.B.,Fox J.W.
Degradation of extracellular matrix proteins by hemorrhagic metalloproteinases.
Arch. Biochem. Biophys.
275
63-71
1989
1142185
Zhang D.,Botos I.,Gomis-Rueth F.-X.,Doll R.,Blood C.,Njoroge F.G.,Fox J.W.,Bode W.,Meyer E.F.
Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d).
Proc. Natl. Acad. Sci. U.S.A.
91
8447-8451
1994
1142186
Botos I.,Scapozza L.,Zhang D.,Liotta L.A.,Meyer E.F.
Batimastat, a potent matrix metalloproteinase inhibitor, exhibits an unexpected mode of binding.
Proc. Natl. Acad. Sci. U.S.A.
93
2749-2754
1996
