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Sequence of DXMT1_COFAR

EC Number:2.1.1.160

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
caffeine synthase
Q8H0D2
Coffea arabica
384
43248
Reaction
S-adenosyl-L-methionine + 1,7-dimethylxanthine = S-adenosyl-L-homocysteine + 1,3,7-trimethylxanthine

General information:

Sequence
show sequence in fasta format
  0 MELQEVLHMN GGEGDTSYAK NSFYNLFLIR VKPILEQCIQ ELLRANLPNI NKCIKVADLG
 60 CASGPNTLLT VRDIVQSIDK VGQEKKNELE RPTIQIFLND LFQNDFNSVF KSLPSFYRKL
120 EKENGCKIGS CLIGAMPGSF YGRLFPEESM HFLHSCYCLH WLSQVPSGLV TELGISANKG
180 CIYSSKASRP PIQKAYLDQF TKDFTTFLRI HSEELISRGR MLLTWICKED EFENPNSIDL
240 LEMSINDLVI EGHLEEEKLD SFNVPIYAPS TEEVKCIVEE EGSFEILYLE TFKVPYDAGF
300 SIDDDYQGRS HSPVSCDEHA RAAHVASVVR SIFEPIVASH FGEAILPDLS HRIAKNAAKV
360 LRSGKGFYDS VIISLAKKPE KADM
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1051618
Mizuno K.,Okuda A.,Kato M.,Yoneyama N.,Tanaka H.,Ashihara H.,Fujimura T.
Isolation of a new dual-functional caffeine synthase gene encoding an enzyme for the conversion of 7-methylxanthine to caffeine from coffee (Coffea arabica L.).
FEBS Lett.
534
75-81
2003
1051619
Uefuji H.,Ogita S.,Yamaguchi Y.,Koizumi N.,Sano H.
Molecular cloning and functional characterization of three distinct N-methyltransferases involved in the caffeine biosynthetic pathway in coffee plants.
Plant Physiol.
132
372-380
2003
1051620
Perrois C.,Strickler S.R.,Mathieu G.,Lepelley M.,Bedon L.,Michaux S.,Husson J.,Mueller L.,Privat I.
Differential regulation of caffeine metabolism in Coffea arabica (Arabica) and Coffea canephora (Robusta).
Planta
241
179-191
2015
1051621
Ashihara H.,Sano H.,Crozier A.
Caffeine and related purine alkaloids: biosynthesis, catabolism, function and genetic engineering.
Phytochemistry
69
841-856
2008