Sequence of SUB1_PLAF7

Subtilisin

Q8I0V0

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Genome sequence of the human malaria parasite Plasmodium falciparum.

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Hall N.,Pain A.,Berriman M.,Churcher C.M.,Harris B.,Harris D.,Mungall K.L.,Bowman S.,Atkin R.,Baker S.,Barron A.,Brooks K.,Buckee C.O.,Burrows C.,Cherevach I.,Chillingworth C.,Chillingworth T.,Christodoulou Z.,Clark L.,Clark R.,Corton C.,Cronin A.,Davies R.M.,Davis P.,Dear P.,Dearden F.,Doggett J.,Feltwell T.,Goble A.,Goodhead I.,Gwilliam R.,Hamlin N.,Hance Z.,Harper D.,Hauser H.,Hornsby T.,Holroyd S.,Horrocks P.,Humphray S.,Jagels K.,James K.D.,Johnson D.,Kerhornou A.,Knights A.,Konfortov B.,Kyes S.,Larke N.,Lawson D.,Lennard N.,Line A.,Maddison M.,Mclean J.,Mooney P.,Moule S.,Murphy L.,Oliver K.,Ormond D.,Price C.,Quail M.A.,Rabbinowitsch E.,Rajandream M.A.,Rutter S.,Rutherford K.M.,Sanders M.,Simmonds M.,Seeger K.,Sharp S.,Smith R.,Squares R.,Squares S.,Stevens K.,Taylor K.,Tivey A.,Unwin L.,Whitehead S.,Woodward J.R.,Sulston J.E.,Craig A.,Newbold C.,Barrell B.G.

Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.

Nature

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527-531

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103918

Yeoh S.,O'Donnell R.A.,Koussis K.,Dluzewski A.R.,Ansell K.H.,Osborne S.A.,Hackett F.,Withers-Martinez C.,Mitchell G.H.,Bannister L.H.,Bryans J.S.,Kettleborough C.A.,Blackman M.J.

Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes.

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Koussis K.,Withers-Martinez C.,Yeoh S.,Child M.,Hackett F.,Knuepfer E.,Juliano L.,Woehlbier U.,Bujard H.,Blackman M.J.

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103920

Silmon de Monerri N.C.,Flynn H.R.,Campos M.G.,Hackett F.,Koussis K.,Withers-Martinez C.,Skehel J.M.,Blackman M.J.

Global identification of multiple substrates for Plasmodium falciparum SUB1, an essential malarial processing protease.

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Thomas J.A.,Tan M.S.Y.,Bisson C.,Borg A.,Umrekar T.R.,Hackett F.,Hale V.L.,Vizcay-Barrena G.,Fleck R.A.,Snijders A.P.,Saibil H.R.,Blackman M.J.

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103922

Tarr S.J.,Withers-Martinez C.,Flynn H.R.,Snijders A.P.,Masino L.,Koussis K.,Conway D.J.,Blackman M.J.

A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1.

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103923

Favuzza P.,de Lera Ruiz M.,Thompson J.K.,Triglia T.,Ngo A.,Steel R.W.J.,Vavrek M.,Christensen J.,Healer J.,Boyce C.,Guo Z.,Hu M.,Khan T.,Murgolo N.,Zhao L.,Penington J.S.,Reaksudsan K.,Jarman K.,Dietrich M.H.,Richardson L.,Guo K.Y.,Lopaticki S.,Tham W.H.,Rottmann M.,Papenfuss T.,Robbins J.A.,Boddey J.A.,Sleebs B.E.,Sabroux H.J.,McCauley J.A.,Olsen D.B.,Cowman A.F.

Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle.

Cell Host Microbe

27

642-0

2020