Sequence of SGK1_RAT
EC Number:2.7.11.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.1
General information:
Sequence
0 MTVKTEAARS TLTYSRMRGM VAILIAFMKQ RRMGLNDFIQ KLANNSYACK HPEVQSYLKI
60 SQPQEPELMN ANPSPPPSPS QQINLGPSSN PHAKPSDFHF LKVIGKGSFG KVLLARHKAE
120 EAFYAVKVLQ KKAILKKKEE KHIMSERNVL LKNVKHPFLV GLHFSFQTAD KLYFVLDYIN
180 GGELFYHLQR ERCFLEPRAR FYAAEIASAL GYLHSLNIVY RDLKPENILL DSQGHIVLTD
240 FGLCKENIEH NGTTSTFCGT PEYLAPEVLH KQPYDRTVDW WCLGAVLYEM LYGLPPFYSR
300 NTAEMYDNIL NKPLQLKNIT NSARHLLEGL LQKDRTKRLG AKDDFMEIKS HIFFSLINWD
360 DLINKKITPP FNPNVSGPSD LRHFDPEFTE EPVPSSIGRS PDSILVTASV KEAAEAFLGF
420 SYAPPMDSFL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
99331
Webster M.K.,Goya L.,Ge Y.,Maiyar A.C.,Firestone G.L.
Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum.
Mol. Cell. Biol.
13
2031-2040
1993
99332
Imaizumi K.,Tsuda M.,Wanaka A.,Tohyama M.,Takagi T.
Differential expression of sgk mRNA, a member of the Ser/Thr protein kinase gene family, in rat brain after CNS injury.
Brain Res. Mol. Brain Res.
26
189-196
1994
99333
Richards J.S.,Fitzpatrick S.L.,Clemens J.W.,Morris J.K.,Alliston T.,Sirois J.
Ovarian cell differentiation: a cascade of multiple hormones, cellular signals, and regulated genes.
Recent Prog. Horm. Res.
50
223-254
1995
99334
Maiyar A.C.,Huang A.J.,Phu P.T.,Cha H.H.,Firestone G.L.
p53 stimulates promoter activity of the sgk. serum/glucocorticoid-inducible serine/threonine protein kinase gene in rodent mammary epithelial cells.
J. Biol. Chem.
271
12414-12422
1996
99335
Park J.,Leong M.L.,Buse P.,Maiyar A.C.,Firestone G.L.,Hemmings B.A.
Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway.
EMBO J.
18
3024-3033
1999
99336
Chen S.-Y.,Bhargava A.,Mastroberardino L.,Meijer O.C.,Wang J.,Buse P.,Firestone G.L.,Verrey F.,Pearce D.
Epithelial sodium channel regulated by aldosterone-induced protein sgk.
Proc. Natl. Acad. Sci. U.S.A.
96
2514-2519
1999
99337
Boehmer C.,Philippin M.,Rajamanickam J.,Mack A.,Broer S.,Palmada M.,Lang F.
Stimulation of the EAAT4 glutamate transporter by SGK protein kinase isoforms and PKB.
Biochem. Biophys. Res. Commun.
324
1242-1248
2004
99338
Yang Y.C.,Lin C.H.,Lee E.H.
Serum- and glucocorticoid-inducible kinase 1 (SGK1) increases neurite formation through microtubule depolymerization by SGK1 and by SGK1 phosphorylation of tau.
Mol. Cell. Biol.
26
8357-8370
2006
99339
Won M.,Park K.A.,Byun H.S.,Kim Y.R.,Choi B.L.,Hong J.H.,Park J.,Seok J.H.,Lee Y.H.,Cho C.H.,Song I.S.,Kim Y.K.,Shen H.M.,Hur G.M.
Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration.
J. Hepatol.
51
67-76
2009
