Sequence of SGK1_MOUSE
EC Number:2.7.11.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.1
General information:
Sequence
0 MTVKAEAARS TLTYSRMRGM VAILIAFMKQ RRMGLNDFIQ KIASNTYACK HAEVQSILKM
60 SHPQEPELMN ANPSPPPSPS QQINLGPSSN PHAKPSDFHF LKVIGKGSFG KVLLARHKAE
120 EVFYAVKVLQ KKAILKKKEE KHIMSERNVL LKNVKHPFLV GLHFSFQTAD KLYFVLDYIN
180 GGELFYHLQR ERCFLEPRAR FYAAEIASAL GYLHSLNIVY RDLKPENILL DSQGHIVLTD
240 FGLCKENIEH NGTTSTFCGT PEYLAPEVLH KQPYDRTVDW WCLGAVLYEM LYGLPPFYSR
300 NTAEMYDNIL NKPLQLKPNI TNSARHLLEG LLQKDRTKRL GAKDDFMEIK SHIFFSLINW
360 DDLINKKITP PFNPNVSGPS DLRHFDPEFT EEPVPSSIGR SPDSILVTAS VKEAAEAFLG
420 FSYAPPVDSF L
Download this sequence
Download all sequences for 2.7.11.1
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
99313
Naray-Fejes-Toth A.,Canessa C.,Cleaveland E.S.,Aldrich G.,Fejes-Toth G.
sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial Na+ channels.
J. Biol. Chem.
274
16973-16978
1999
99314
Shigaev A.,Asher C.,Latter H.,Garty H.,Reuveny E.
Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channel.
Am. J. Physiol.
278
0-0
2000
99315
Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.
The transcriptional landscape of the mammalian genome.
Science
309
1559-1563
2005
99317
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
99318
Maiyar A.C.,Huang A.J.,Phu P.T.,Cha H.H.,Firestone G.L.
p53 stimulates promoter activity of the sgk. serum/glucocorticoid-inducible serine/threonine protein kinase gene in rodent mammary epithelial cells.
J. Biol. Chem.
271
12414-12422
1996
99319
Leong M.L.L.,Maiyar A.C.,Kim B.,O'Keeffe B.A.,Firestone G.L.
Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells.
J. Biol. Chem.
278
5871-5882
2003
99320
Yoo D.,Kim B.Y.,Campo C.,Nance L.,King A.,Maouyo D.,Welling P.A.
Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A.
J. Biol. Chem.
278
23066-23075
2003
99321
Strutz-Seebohm N.,Seebohm G.,Shumilina E.,Mack A.F.,Wagner H.J.,Lampert A.,Grahammer F.,Henke G.,Just L.,Skutella T.,Hollmann M.,Lang F.
Glucocorticoid adrenal steroids and glucocorticoid-inducible kinase isoforms in the regulation of GluR6 expression.
J. Physiol. (Lond.)
565
391-401
2005
99322
Amato R.,D'Antona L.,Porciatti G.,Agosti V.,Menniti M.,Rinaldo C.,Costa N.,Bellacchio E.,Mattarocci S.,Fuiano G.,Soddu S.,Paggi M.G.,Lang F.,Perrotti N.
Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.
J. Mol. Med.
87
1221-1239
2009
99323
Catela C.,Kratsios P.,Hede M.,Lang F.,Rosenthal N.
Serum and glucocorticoid-inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis.
Dev. Dyn.
239
2149-2160
2010
99324
Heise C.J.,Xu B.E.,Deaton S.L.,Cha S.K.,Cheng C.J.,Earnest S.,Sengupta S.,Juang Y.C.,Stippec S.,Xu Y.,Zhao Y.,Huang C.L.,Cobb M.H.
Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.
J. Biol. Chem.
285
25161-25167
2010
99325
Di Pietro N.,Panel V.,Hayes S.,Bagattin A.,Meruvu S.,Pandolfi A.,Hugendubler L.,Fejes-Toth G.,Naray-Fejes-Toth A.,Mueller E.
Serum- and glucocorticoid-inducible kinase 1 (SGK1) regulates adipocyte differentiation via forkhead box O1.
Mol. Endocrinol.
24
370-380
2010
99326
Eylenstein A.,Gehring E.M.,Heise N.,Shumilina E.,Schmidt S.,Szteyn K.,Muenzer P.,Nurbaeva M.K.,Eichenmueller M.,Tyan L.,Regel I.,Foeller M.,Kuhl D.,Soboloff J.,Penner R.,Lang F.
Stimulation of Ca2+-channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1).
FASEB J.
25
2012-2021
2011
99327
Lu M.,Wang J.,Ives H.E.,Pearce D.
mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel.
J. Biol. Chem.
286
30647-30654
2011
99328
Mo J.S.,Ann E.J.,Yoon J.H.,Jung J.,Choi Y.H.,Kim H.Y.,Ahn J.S.,Kim S.M.,Kim M.Y.,Hong J.A.,Seo M.S.,Lang F.,Choi E.J.,Park H.S.
Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase.
J. Cell Sci.
124
100-112
2011
99329
He P.,Lee S.J.,Lin S.,Seidler U.,Lang F.,Fejes-Toth G.,Naray-Fejes-Toth A.,Yun C.C.
Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids.
Mol. Biol. Cell
22
3812-3825
2011